Boosting Executive Function With Brain Exercise

NCT06482047 | Not Yet Recruiting

• 1 other identifier: ShenzhenUExerciseIntervention
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to explore the impact of a 15-minute exercise break on brain function and cognitive performance in a simulated classroom setting. The main questions it aims to answer are:

1. 1.How do short exercise breaks affect executive function in college students?
2. 2.What changes occur in brain connectivity and microcirculation after these exercise breaks? Participants were college students who engaged in sessions of continuous sitting or sitting interspersed with exercise. The study used cognitive tasks and brain imaging techniques to measure the effects. The findings reveal improvements in cognitive performance and brain function, suggesting that short exercise breaks are beneficial in educational contexts.

Conditions

Sedentary Behavior

Outcome Measures

Primary Outcomes (3)

• Cognitive function

  This primary outcome measure is assessed by the modified dual-task Stroop paradigm.

  3 weeks

• Retinal Vessel Diameter

  Retinal Vessel Diameter is assessed by the fully automated fundus camera.

  3 weeks

• Brain Connectivity

  Brain connectivity is assessed by the NIRSport2 device

  3 weeks

Study Arms (3)

Moderate-intensity cycling

EXPERIMENTAL

Moderate-intensity cycling on Ergoline Ergoselect 100

Behavioral: Moderate-intensity cycling; Behavioral: Uninterrupted sitting

Vigorous-intensity cycling

EXPERIMENTAL

Vigorous-intensity cycling on Ergoline Ergoselect 100

Behavioral: Vigorous-intensity cycling; Behavioral: Uninterrupted sitting

Uninterrupted sitting

EXPERIMENTAL

Uninterrupted sitting in a quiet room

Behavioral: Uninterrupted sitting

Interventions

Moderate-intensity cycling BEHAVIORAL

Moderate-intensity cycling on Ergoline Ergoselect 100

Moderate-intensity cycling

Vigorous-intensity cycling BEHAVIORAL

Vigorous-intensity cycling on Ergoline Ergoselect 100

Vigorous-intensity cycling

Uninterrupted sitting BEHAVIORAL

Uninterrupted sitting in a quiet room

Moderate-intensity cycling; Uninterrupted sitting; Vigorous-intensity cycling

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• right-handed (how was handedness assessed; i.e., "What hand do you write with?") with normal or corrected-to-normal vision and normal color vision

You may not qualify if:

• reported a history of cardiovascular, metabolic, gastrointestinal, neurological, or psychiatric disorders, medical conditions requiring medical care, substance addiction, strict diets (e.g., low- carbohydrate and Mediterranean diet), pregnancy, or lactation.

Sponsors & Collaborators

• Liye Zou: lead

Study Sites (1)

Body-Brain-Mind Laboratory, School of Psychology, Shenzhen University

Shenzhen, China

Location

MeSH Terms

Conditions

Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Central Study Contacts

Liye Zou, Dr.

CONTACT

18823437684; liyezou123@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Model Details: The study used a within-participant cross-over design with pre-and post-test comparisons. Participants completed the three following experimental conditions in pseudo-counterbalanced (cannot be completely counterbalanced given that an odd number of participants - hence, was pseudo-counterbalanced) order (odd number of participants) with at least a 7-day washout period between conditions: (i) 115-minute uninterrupted sitting \[control\]; (ii) 50-minute sitting + 15-minute moderate-intensity cycling + 50-minute sitting \[experimental condition 1\]; (iii) 50-minute sitting + 15-minute vigorous-intensity cycling + 50-minute sitting \[experimental condition 2\]. A familiarization session was completed about three days before the experiment started, during which participants were familiarized with the cognitive assessment and cycling protocols.

Study Record Dates

• First Submitted: January 3, 2024
• First Posted: July 1, 2024
• Study Start: July 2, 2024
• Primary Completion: March 30, 2025
• Study Completion: April 15, 2025
• Last Updated: July 1, 2024

Record last verified: 2024-06

Locations

CN (1)