NCT06730646

Brief Summary

Young adults are particularly vulnerable to psychological distress during the transition from adolescence to adulthood, making them more susceptible to developing persistent substance use. The tobacco industry capitalizes on this vulnerability by using marketing tactics to promote tobacco initiation and facilitate the progression from experimental tobacco use to long-term use. In China, where the average age of starting daily smoking is 21.1 years old, the number of current young adult smokers exceeds 29 million. It is crucial to develop effective communication messages to counter the tobacco industry's marketing strategies and protect the health of young adults in China. This project aims to test the effects of different anti-smoking message themes among Chinese young adults. In this online randomized clinical trial, participants will be randomly assigned to one of five antismoking message conditions. The investigators will compare the effects of these themes with each other and with the control condition.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,541

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
2 countries

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 8, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 12, 2024

Completed
9 months until next milestone

Study Start

First participant enrolled

September 1, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2025

Completed
Last Updated

October 14, 2025

Status Verified

October 1, 2025

Enrollment Period

1 month

First QC Date

December 8, 2024

Last Update Submit

October 9, 2025

Conditions

Keywords

anti-smokinghealth communicationsmoking behavior

Outcome Measures

Primary Outcomes (1)

  • Intention to use tobacco

    A five-item scale measuring future intentions to smoke cigarettes and other forms of tobacco over the next year. Response options: from 1 (very unlikely) to 5 (very likely). Higher scores represent stronger intention to use tobacco.

    Immediately after message exposure

Secondary Outcomes (5)

  • Perceived harm of smoking

    Immediately after message exposure

  • Perceived Message Effectiveness

    Immediately after message exposure

  • Quit intention

    Immediately after message exposure

  • Smoking behavior

    Two weeks after message exposure

  • Intention to use tobacco in follow-up test

    Two weeks after message exposure

Study Arms (6)

Health effects

EXPERIMENTAL

Participants will receive messages with information about smoking-related diseases.

Behavioral: Health effects

Tobacco industry manipulation

EXPERIMENTAL

Participants will receive messages with information about how the tobacco industry uses targeted marketing and manipulative tactics aimed at youth and young adults.

Behavioral: Tobacco industry manipulation

Secondhand smoke

EXPERIMENTAL

Participants will receive messages with information about secondhand smoke exposure.

Behavioral: Secondhand smoke

Mental Health

EXPERIMENTAL

Participants will receive messages with information about the effects of smoking on mental health.

Behavioral: Mentral health

Social acceptability

EXPERIMENTAL

Participants will receive messages that portray smoking as socially unacceptable in China.

Behavioral: Social acceptability

Control

OTHER

Participants will receive messages about bottled water which should have no impact on the outcomes of interest.

Behavioral: Control

Interventions

Health effectsBEHAVIORAL

Participants in this arm will watch 3 short videos about the smoking-related diseases during the survey data collection.

Health effects

Participants in this arm will watch 3 short videos about how the tobacco industry uses targeted marketing and manipulative tactics aimed at youth and young adults during the survey data collection.

Tobacco industry manipulation

Participants in this arm will watch 3 short videos about the risks of secondhand smoke exposure during the survey data collection.

Secondhand smoke
Mentral healthBEHAVIORAL

Participants in this arm will watch 3 short videos about the effects of smoking on mental health during the survey data collection.

Mental Health

Participants in this arm will watch 3 short videos about how smoking is socially unacceptable in China during the survey data collection.

Social acceptability
ControlBEHAVIORAL

Participants in this arm will watch 3 short videos about drinking bottled water during the survey data collection. These messages display specific water products and describe hydration as a healthy activity.

Control

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Aged between 18-25 years old
  • Current residency in China
  • Current smokers - having smoked at least 100 cigarettes in a lifetime and currently smoking every day or some days
  • Nonsmokers - having not smoked 100 cigarettes in a lifetime and do not currently smoke cigarettes
  • Can to read, speak, and understand Mandarin Chinese

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Georgia State university

Atlanta, Georgia, 30303, United States

Location

Online

Shanghai, Shanghai Municipality, 200433, China

Location

MeSH Terms

Conditions

Smoking

Interventions

Tobacco Smoke Pollution

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

SmokeParticulate MatterComplex MixturesAir PollutionEnvironmental PollutionPublic HealthEnvironment and Public Health

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Postdoctoral Research Associate

Study Record Dates

First Submitted

December 8, 2024

First Posted

December 12, 2024

Study Start

September 1, 2025

Primary Completion

October 1, 2025

Study Completion

October 1, 2025

Last Updated

October 14, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

Locations