Estimating Fluid Requirement in Shocked Traumatic Patients by US on SCV

NCT06726668 | Not Yet Recruiting DMC

• 1 other identifier: US Subclavian vein Shock
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Research question Is the ultrasonographic SCV collapsability index effective in estimating fluid requirements in shocked traumatic Patients ? Purpose of the study To evaluate the effectiveness of ultrasonograghic SCV collapsibility index before and after the first hour of resuscitation in estimating the First 24 h of fluid requirement in shocked traumatic patients.

Conditions

Shock; Trauma

Keywords

Us; Subclavian vein; Shock; Trauma

Outcome Measures

Primary Outcomes (1)

• To estimate and predict the fluid requirement using ultrasonograghic Sub Clavian vein collapsibility index before and after the first hour of resuscitation

  In the first hour of resuscitation, the patients (unstable shocked) will be given 1 L of crystalloid solution for fluid resuscitation ( according to recent ATLS guidelines). If the patient is still unstable after 1 Liter of fluid or had ongoing blood loss, O- negative blood transfusion will be administered and type-specific blood Will be ordered and the trauma team activated massive transfusion protocol according to recent ATLS Guidelines even if normal hemoglobin. The traumatic patients after 1 h of resuscitation were divided into two groups (SCV non -Repleted) and (SCV Repleted) group as (if thereis still an SCV diameter of \< 7 mm after the first hour of resuscitation they are called (the SCV non -Repleted) group. And if the SCV diameter of ≥ 7 mm after the first hour of resuscitation) they are called the (SCV Repleted) group.

  Before resuscitation and after 1 hour of resuscitation

Secondary Outcomes (2)

• To estimate and predict the First 24-h fluid requirement using repeated ultrasonograghic SCV collapsibility index.

  In the first 24 hours of resuscitation

• -To assess the role of ultrasonograghic SCV CI in rapidly detecting early shock stages.

  In the first 24 hours of resuscitation

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Total coverage sample of all traumatic patients who will be admitted to emergency department Assiut university who fulfill the inclusion criteria during study period of 12 months from 1st of March 2025 to 1st of March 2026.

You may qualify if:

• Traumatic patients who will come to emergency department at Assiut university Hospital between march 2025 to march 2026 and will be admitted after stabilization to the Inpatient ward or ICU

You may not qualify if:

• Patients or their Relatives refuse participation in the study.
• Patients who will be transferred to another hospital
• Pregnant women.
• Age below 18 and more than 60.
• Failure of follow-up of any patient.
• Cardiopulmonary resuscitation on arrival.
• Contraindicating fluid challenges, such as cardiac insufficiency and Renal failure .

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University

Asyut, 71515, Egypt

Location

MeSH Terms

Conditions

Shock; Wounds and Injuries

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Mohamed A Mohamed Abdelhameed, Resident

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed A Mohamed Abdelhameed, Resident

CONTACT

+201156140325; mohammed1331998@gmail.com

Fatma A Abdelal, Professor

CONTACT

+201113221317; fatmaabdelal@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Emergency medicine resident physician at Assiut University Hospitals

Study Record Dates

• First Submitted: December 6, 2024
• First Posted: December 10, 2024
• Study Start: March 1, 2025
• Primary Completion: March 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: December 10, 2024

Record last verified: 2024-12

Locations

EG (1)