NCT06723262

Brief Summary

Main objective: Compare speech recognition in noise with tonotopic fitting (FS4T) and with conventional non-tonotopic fitting (FS4noT) in adult patients implanted for 6 months with a MED-EL cochlear implant with FS4noT strategy. Secondary objectives: Comparison of FS4noT and FS4T settings

  • for speech recognition in quiet
  • for subjective auditory spatial perception

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
27mo left

Started Jan 2025

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress39%
Jan 2025Jun 2028

First Submitted

Initial submission to the registry

December 4, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 9, 2024

Completed
23 days until next milestone

Study Start

First participant enrolled

January 1, 2025

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2028

Last Updated

May 6, 2026

Status Verified

April 1, 2026

Enrollment Period

3.5 years

First QC Date

December 4, 2024

Last Update Submit

April 30, 2026

Conditions

Keywords

cochlear implant strategy anatomy-based fitting

Outcome Measures

Primary Outcomes (1)

  • Speech recognition in noise

    Framatrix test. Speech and noise in front the participant (at 1m). Noise level: 65 dB SPL. Speech level: adaptive with the answers of the participant. Result: speech-to-noise ratio (speech reception threshold, SRT50) for 50% of intelligibility in noise. Test with FS4T and with FS4noT

    6 weeks after FS4T fitting

Secondary Outcomes (2)

  • Speech recognition in quiet

    6 weeks after FS4T fitting

  • Subjective auditory spatial perception

    At FS4T fitting and 6 weeks after FS4T fitting

Study Arms (1)

ABF arm

OTHER

At 6 month post-activation: tonotopic fitting FS4T the participant wears FS4T during 6 weeks.

Other: Tonotopic cochlear implant fitting FS4T

Interventions

Comparison of FS4T and FS4noT

Also known as: No tonotopic cochlear implant fitting FS4noT
ABF arm

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patient (\>= 18 years old) speaking French
  • Patient who fulfils the criteria for cochlear implantation

You may not qualify if:

  • retro-cochlear pathology: auditory neuropathy, vestibular schwannoma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU

Limoges, 87000, France

RECRUITING

MeSH Terms

Conditions

Hearing Loss, Sensorineural

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Karine Aubry, Pr

    University Hospital, Limoges

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Vincent Péan, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 4, 2024

First Posted

December 9, 2024

Study Start

January 1, 2025

Primary Completion (Estimated)

June 30, 2028

Study Completion (Estimated)

June 30, 2028

Last Updated

May 6, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations