Repeated Injection of I PRF and Autogenous Bone Graft for Alveolar Ridge Augmentation

NCT06711250 | Completed DMC

• 1 other identifier: alveolar ridge augmenation
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

The current st udy's objective was to validate the repeated effect of i PRF with autogenous bone on the of gingival thickness , width a n d volumetric bone changes durig maxillary alveolar augmentation using cone beam computer tomography (CBCT). Patients and methods:

Conditions

Alveolar Bone Loss; Alveolar Ridge Abnormality

Keywords

A lveolar ridge defect , Khoury technique Guided bone regeneration, i PRF, CBCT analysis

Outcome Measures

Primary Outcomes (1)

• width of the alveolar ridge

  CBCT will be used to assess the width of the alveolar ridge

  baseline, 6 months & 9 months

Secondary Outcomes (1)

• volumetric analysis of bone

  at baseline, 6 and 9 months

Study Arms (2)

control

ACTIVE COMPARATOR

bone grafting

Procedure: khoury technique

study

ACTIVE COMPARATOR

bone grafting \& i PRF

Procedure: khoury technique with i-PRF injections

Interventions

khoury technique PROCEDURE

autogenous bone augmentation

control

khoury technique with i-PRF injections PROCEDURE

autogenous bone augmentation with repeated i-PRF injections

study

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• patients who have a horizontal or vertical alveolar ridge deficiency

You may not qualify if:

• patients showing any signs of active periodontal disease
• patients on long term corticosteroid therapy,
• patients taking bone metabolism drugs
• patients suffering from any systemic illness that may impact bone repair

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Faculty of Dentistry , Al Azhar Univeristy For Girls

Cairo, Heliopolis - Cairo, 123456, Egypt

Location

MeSH Terms

Conditions

Alveolar Bone Loss

Condition Hierarchy (Ancestors)

Bone Resorption; Bone Diseases; Musculoskeletal Diseases; Periodontal Atrophy; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Study Officials

• Zainab H Abdel Rahman, Phd

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 22, 2024
• First Posted: December 2, 2024
• Study Start: April 1, 2024
• Primary Completion: September 1, 2024
• Study Completion: November 1, 2024
• Last Updated: December 2, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)