Median Nerve Thickness of the Carpal Tunnel Syndrome After Two Different Physiotherapy Modalities

NCT07167667 | Recruiting

• 1 other identifier: 2024/145
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The study plans to include a total of 60 patients diagnosed with carpal tunnel syndrome. Patients will be divided into two groups according to the treatment they receive. One group will receive only paraffin treatment, while the other group will receive only ESWT treatment. ESWT will be applied for a total of 5 sessions. Paraffin will be applied for a total of 10 sessions. As assessment tools;

• Measurement of median nerve thickness with ultrasound
• Electromyography
• Visual Analog Scale
• Short Form-36 Evaluations will be made twice by a specialist physician before and after the treatments.

Conditions

Carpal Tunnel Syndrome (CTS)

Keywords

Median Nerve Thickness; Ultrasound; Electromyograpy; Physiotherapy; ESWT; Paraffin

Outcome Measures

Primary Outcomes (2)

• Median Nerve Thickness

  Median nerve thickness will be measured by ultrasound

  Baseline

• Median Nerve Thickness

  Median nerve thickness will be measured by ultrasound

  5 days later for the first ESWT intervention and 10 days later for the first Paraffin Intervention

Secondary Outcomes (5)

• Electromyography

  Baseline

• Visual Analog Scale

  Baseline

• Visual Analog Scale

  5 days later for the first ESWT intervention and 10 days later for the first Paraffin Intervention

• Short Form-36

  Baseline

• Short Form-36

  5 days later for the first ESWT intervention and 10 days later for the first Paraffin Intervention

Study Arms (2)

Paraffin

EXPERIMENTAL

Other: Paraffin Bath

ESWT

EXPERIMENTAL

Other: Extracorporeal Shock Wave Therapy

Interventions

Paraffin Bath OTHER

Patients' hands will be dipped into the paraffin bath 8-10 times.

Paraffin

Extracorporeal Shock Wave Therapy OTHER

The patients will be treated with a sound wave pulse frequency of 15 Hz, an intensity of 1.5 bar, and a total number of pulses of 2000 for one session.

ESWT

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Individuals between the ages of 30-60 who have been diagnosed with CTS by a specialist physician according to international criteria (Those between Stages 1-3),
• Those who have complaints of numbness, tingling, and pain in the first three fingers and half of the fourth finger,
• Phalen Test and Tinel sign or Durkan Test being positive
• Patients who will receive 5 sessions of ESWT application prescribed by a Physical Medicine and Rehabilitation Specialist Physician (for the ESWT group)
• Patients who have been recommended 10 sessions of Paraffin application by a Physical Medicine and Rehabilitation Specialist Physician (for the Paraffin group)

You may not qualify if:

• Presence of atrophy in the thenar muscles,
• Insufficient sensory and motor response in the median nerve,
• History of hand and/or wrist injury or surgery,
• Those with cervical stenosis, cervical spondylosis, or cervical radiculopathy,
• Corticosteroids in the carpal tunnel area within the last six months those who have had an injection,
• Pregnancy or diabetes, renal failure, rheumatoid arthritis or hypothyroidism

Sponsors & Collaborators

• Emre Şenocak: lead

Study Sites (1)

Baltalimani Metin Sabanci Bone Diseases Training and Research Hospita

Istanbul, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Extracorporeal Shockwave Therapy

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Ultrasonic Therapy; Diathermy; Hyperthermia, Induced; Therapeutics; Physical Therapy Modalities; Rehabilitation

Central Study Contacts

Esra Sonbahar Bolat, Physician

CONTACT

+9005052686709; esra.sonbahar@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: June 11, 2025
• First Posted: September 11, 2025
• Study Start: October 25, 2024
• Primary Completion: October 25, 2025
• Study Completion: October 25, 2025
• Last Updated: September 11, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)