Comparison of Post-operative Pain After Use of Endo-activator and Conventional Irrigation During Endodontic Treatment in Symptomatic Periapical Periodontitis

NCT06668662 | Completed

• 1 other identifier: JSMU/IRB/2023/714
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Introduction: The adequate removal of microorganisms, infected or necrotic pulp tissues and complete adequate seal of root canal system along with debridement is key to success of endodontic treatment. The objective of this study was to compare frequency of pain after using Endo Activator and conventional irrigation in patients presenting with symptomatic periapical periodontitis following endodontic treatment by means of Visual Analog Scale. Methods: This study was designed as single blind, randomized control trial. Sixty patients with symptomatic teeth requiring endodontic canal treatment were recruited by probability random sampling into two groups based on irrigation protocols used during endodontic treatment: conventional needle and endo activator irrigation system. The post-operative pain of patients was recorded via a telephone call at 6 hours, 24 hours, and at 7 days on the visual analogue scale (VAS).

Conditions

Post Operative Pain; Endodontic Treatment; Apical Periodontitis

Keywords

Conventional irrigation; Endoactivator; Post- operative pain; symptomatic periapical periodontitis; Visual Analogue Scale

Outcome Measures

Primary Outcomes (3)

• Comparison of post-operative pain after use of Endo-activator and conventional irrigation during endodontic treatment in symptomatic periapical periodontitis: a randomized control trial.

  Introduction: The adequate removal of microorganisms, infected or necrotic pulp tissues and complete adequate seal of root canal system along with debridement is key to success of endodontic treatment. The objective of this study was to compare frequency of pain after using Endo Activator and conventional irrigation in patients presenting with symptomatic periapical periodontitis following endodontic treatment by means of Visual Analog Scale. Methods: This study was designed as single blind, randomized control trial .Sixty patients with symptomatic teeth requiring endodontic canal treatment were recruited by probability random sampling into two groups based on irrigation protocols used during endodontic treatment: conventional needle and endo activator irrigation system. The post-operative pain of patients was recorded via a telephone call at 6 hours, 24 hours, and at 7 days on the visual analogue scale (VAS).

  6 hours, 24 hours, and at 7 days

• Endoactivator

  conventional endodontic needle 4 mL of 2.5% NaOCl was delivered into pulp chamber and then an Endoactivator tip (size #15.02) (DENTSPLY/ Tulsa Dental Specialties, OK) was placed loosely 2 mm short of working length, and activated at 20000 Hz in each canal, moving in a constant in and out motion. The NaOCl was agitated for one minute with approximately 2-3 mm vertical strokes.

  The patients were contacted via telephone after 6 hours, 24 hours and 7 days to ask and record their postoperative pain on visual analogue scale that consist of 10cm line anchored by 1 denoting mild and 10 being most severe.

• Conventional irrigation

  by placing the needle 2 mm short of desired working length, 4 mL of 2.5% NaOCl was placed into each canal for 40 secs with an approximate flow rate of 0.1 mL/s.

  The patients were contacted via telephone after 6 hours, 24 hours and 7 days to ask and record their postoperative pain on visual analogue scale that consist of 10cm line anchored by 1 denoting mild and 10 being most severe.

Study Arms (2)

endoactivator

ACTIVE COMPARATOR

Endoactivator is an irrigation technique which will help to reduce post-operative pain in patients following endodontic treatment.

Device: Endoactivator

Conventional irrigation

ACTIVE COMPARATOR

Conventional irrigation is an irrigation technique which will help to reduce post-operative pain in patients following endodontic treatment.

Device: Conventional irrigation

Interventions

Endoactivator DEVICE

Endoactivator is an irrigation technique which will help to reduce post-operative pain in patients following endodontic treatment.

endoactivator

Conventional irrigation DEVICE

Conventional irrigation is an irrigation technique which will help to reduce post-operative pain in patients following endodontic treatment.

Conventional irrigation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients not taking any sedative or analgesics medication 48 hours prior to presenting to the dental clinic
• The teeth that were included were tender to percussion and palpation but had a sound periodontium and no inflammatory exudate or pus drainage.

You may not qualify if:

• Patients with any systemic diseases,
• retreatment cases,
• or teeth with calcified canals were excluded

Sponsors & Collaborators

• Jinnah Sindh Medical University: lead

Study Sites (1)

Sindh Institute of Oral Health Sciences Jinnah Sindh Medical University Karachi

Karachi, Sindh, 75510, Pakistan

Location

Related Publications (1)

• 1. Salim A, Darrag A, Ghoneim W. Post-Operative Pain after Single-Visit Endodontic treatment using different root canal irrigation activating techniques. Egypt Dent J. 2021;67(4):3719-30.

  RESULT

MeSH Terms

Conditions

Pain, Postoperative; Periapical Periodontitis

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms; Periapical Diseases; Jaw Diseases; Stomatognathic Diseases; Periodontal Diseases; Mouth Diseases; Periodontitis

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: October 30, 2024
• First Posted: October 31, 2024
• Study Start: September 1, 2023
• Primary Completion: March 31, 2024
• Study Completion: March 31, 2024
• Last Updated: October 31, 2024

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will share

Locations

PA (1)