Effect of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment

NCT07062419 | Completed DMC FDA Device

• 1 other identifier: 107/Civ/Trg/Op/15/24
• Study Type: interventional
• Target: 58
• Locations: 1 country
• Sites: 1

Brief Summary

Fifty-eight patients aged 18-60 years, diagnosed with symptomatic or asymptomatic apical periodontitis will be randomly allocated into two groups: Group A (EndoActivator) and Group B (conventional syringe irrigation). preoperative pain will be evaluated in all patients requiring root canal treatment using visual analogue scale before initiating the procedure. Postoperative pain will be measured using the Visual Analog Scale (VAS) at 24, 36, 48 hours and one week.

Conditions

Post Operative Pain; Root Canal Therapy

Outcome Measures

Primary Outcomes (2)

• post operative pain using endoactivator

  post operative pain will be marked on visual analogue scale (VAS). the lower the score the less pain will be and vice versa. maximum score 10 minimum score 0 0 to 10 depicting no pain to worst pain

  before procedure, after 24 hours, 36 hours , 48 hours, 1 week

• post operative pain

  pain will be evaluatedon visual analogue scale (VAS). the lower the score the less pain will be and vice versa. maximum score 10 minimum score 0 0 to 10 depicting no pain to worst pain

  before procedure, after 24 hours , 36 hours , 48 hours , 1 week

Study Arms (2)

one group will receive irrigation during root canal treatment will be activated by an Endoactivator

EXPERIMENTAL

activation of an irrigant by using certain ultrasonic frequency to enhance antimicrobial action of irrigant

Device: endoactivator

One group will receive irrigation during root canal treatment in which activation will not occur

NO INTERVENTION

This group consists of patients who will receive irrigation during root canal treatment using the conventional syringe irrigation technique without the use of the EndoActivator system.

Interventions

endoactivator DEVICE

activation of irrigant during root canal treatment

one group will receive irrigation during root canal treatment will be activated by an Endoactivator

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• irreversible pulpitis
• symptomatic apical periodontitis
• asymptomatic apical periodontitis
• compliant patients
• sufficient ferrule for post operative restoration

You may not qualify if:

• periapical abcess
• severe periodontal disease with guarded periodontal prognosis
• teeth with guarded post operative restoration prognosis
• non compliant patients

Sponsors & Collaborators

• CMH Lahore Medical College and Institute of Dentistry: lead

Study Sites (1)

28 Military Dental Centre

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Officials

• Imran Khan, BDS FCPS

  28 military dental centre

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 20, 2025
• First Posted: July 14, 2025
• Study Start: January 1, 2025
• Primary Completion: July 25, 2025
• Study Completion: August 30, 2025
• Last Updated: October 1, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)