NCT06664034

Brief Summary

The purpose of this pilot study is to evaluate the feasibility of a multi-component intervention to improve young female cancer survivors' engagement in goal-concordant reproductive health care. The investigators hypothesize that implementation of the intervention will result in increased young cancer survivors' engagement in goal-concordant reproductive health care.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P25-P50 for not_applicable cancer

Timeline
1mo left

Started Dec 2024

Geographic Reach
1 country

4 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress96%
Dec 2024May 2026

First Submitted

Initial submission to the registry

October 27, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 29, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

December 1, 2024

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2026

Last Updated

September 4, 2025

Status Verified

August 1, 2025

Enrollment Period

1.5 years

First QC Date

October 27, 2024

Last Update Submit

August 27, 2025

Conditions

Keywords

Reproductive healthOncofertility

Outcome Measures

Primary Outcomes (1)

  • Proportion of patient's engagement in goal-concordant reproductive health care

    Study staff will be trained to abstract the primary outcome from the patient's medical records using standardized case report forms. Engagement in goal-concordant reproductive health care will be assigned to patients who undergo: 1) reproductive health needs screen and have no needs, OR 2) reproductive health needs screen, complete a navigation session and receive reproductive health counseling and management strategies, and have no further needs; OR 3) reproductive health needs screen, complete a navigation session and receive reproductive health counseling and management strategies, have a need, undergo a telehealth reproductive health consultation, and have no reproductive health service needs; OR 4) reproductive health needs screen, complete a navigation session and receive reproductive health counseling and management strategies, have a need, undergo a telehealth reproductive health consultation, have a reproductive health service needs, and uptake appropriate services.

    12 weeks after oncology visit

Study Arms (1)

Multi-component intervention

EXPERIMENTAL

After the intervention implementation, all cancer patients presenting to oncology clinical visits that meet eligibility criteria will receive the multi-component intervention.

Behavioral: Multi-component reproductive health care intervention

Interventions

The multi-component reproductive health care intervention includes: 1. Young cancer patients presenting to oncology visits will complete a clinic-based reproductive health needs screen with a member of the clinical team. This needs screen assesses i) desire to have a child in the future and ii) need for contraception. 2. Reproductive health patient navigation consists of one telehealth or in-person session with a social worker to: i) assess the patient's reproductive health needs, ii) provide individualized patient education and counseling on a) infertility risk related to cancer type and treatment and b) screening and management strategies for reproductive health needs, iii) provide support with the goal of engaging in goal-concordant reproductive health care. 3. Telehealth reproductive health consultation will occur between the patient and reproductive specialist. Each consultation is estimated to be 1 hour.

Multi-component intervention

Eligibility Criteria

Age15 Years - 50 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Cancer (Stages 0-IV) diagnosis
  • Primary language English or Spanish
  • Receiving oncology care at rural oncology clinical participating site
  • Living in Imperial County, California

You may not qualify if:

  • \- Women who are pregnant at recruitment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

San Diego State University - Imperial Valley/ School of Nursing

Brawley, California, 92227, United States

ACTIVE NOT RECRUITING

Cancer Resource Center of the Desert

El Centro, California, 92243, United States

ACTIVE NOT RECRUITING

El Centro Regional Medical Center

El Centro, California, 92243, United States

RECRUITING

University of Califiornia San Diego

La Jolla, California, 92093, United States

ACTIVE NOT RECRUITING

MeSH Terms

Conditions

NeoplasmsInfertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

  • H. Irene Su, MD, MSCE

    University of California, San Diego

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sally Romero, PhD, MPH

CONTACT

H. Irene Su, MD, MSCE

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Model Details: single arm pilot hybrid type I trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

October 27, 2024

First Posted

October 29, 2024

Study Start

December 1, 2024

Primary Completion (Estimated)

May 31, 2026

Study Completion (Estimated)

May 31, 2026

Last Updated

September 4, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will share

Deidentified individual participant data generated during the study will be available from the principal investigator (H. Irene Su) upon reasonable request.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication.
Access Criteria
Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to the principal investigator (H. Irene Su).

Locations