Malnutrition is a Severe Health Issue for Cancer Patients. This Study Examines How Preoperative Nutritional Status Affects Postoperative Delirium in Patients Undergoing Major Abdominal Surgery for Gynecological and Gastrointestinal Tumors.

NCT06657599 | Completed

• 1 other identifier: Hazel06
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

The World Health Organization (WHO) identifies malnutrition as a significant public health threat. It is a common issue among cancer patients due to various factors. Specific nutrient deficiencies can lead to severe cognitive problems. This study aims to evaluate the impact of preoperative nutritional status on the frequency of postoperative delirium. Additionally, we will compare different parameters that can be used to diagnose preoperative malnutrition. We included a total of 120 patients aged over 18 years, classified as ASA I-IV, who were undergoing major abdominal surgery for gynecological or gastrointestinal tumors and were expected to remain in the postoperative care unit for more than 24 hours. The patients' preoperative scores, albumin levels, prealbumin levels, and other relevant data were recorded. In the first 24 hours post-surgery, delirium was assessed using the Ramsay Sedation Scale and the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).

Conditions

Surgery; Malnutrition; Delirium, Postoperative; Abdominal Neoplasm

Outcome Measures

Primary Outcomes (1)

• CAM-ICU

  The confusion assessment method for the intensive care unit (CAM-ICU) is a tool used to assess delirium among patients in the intensive care unit.

  24 hours

Interventions

Major Abdominal Surgery PROCEDURE

Patients with ASA I-IV, over 18 years of age, undergoing major abdominal surgery, have gynecological and GIS tumor, expected to stay in postoperative care unit for more than 24 hours.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients undergoing major abdominal surgery, have gynecological and GIS tumor, expected to stay in postoperative care unit for more than 24 hours.

You may qualify if:

• ASA I-IV
• Over 18 years of age
• Undergoing major abdominal surgery for gynecological and GIS tumor
• Expected to stay in postoperative care unit for more than 24 hours

You may not qualify if:

• Under age 18.
• Patients scheduled for emergency surgery, pregnancy, who want to withdraw from postoperative work.
• Patients with dementia, Alzheimer, psychiatric illness, illiterate people.
• Patients with speech, vision and hearing problems.
• Patients with a history of alcoholism.
• Patients who need postoperative mechanical ventilation support (patients who develop heart or respiratory failure due to COPD, heart failure, pulmonary embolism and similar reasons)

Sponsors & Collaborators

• Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital: lead

Study Sites (1)

Ozlem Sen

Ankara, 06000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Malnutrition; Emergence Delirium; Abdominal Neoplasms

Condition Hierarchy (Ancestors)

Nutrition Disorders; Nutritional and Metabolic Diseases; Delirium; Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Neurocognitive Disorders; Mental Disorders; Neoplasms by Site; Neoplasms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiology and Reanimation Specialist MD.

Study Record Dates

• First Submitted: August 27, 2024
• First Posted: October 24, 2024
• Study Start: June 1, 2017
• Primary Completion: August 1, 2018
• Study Completion: August 1, 2018
• Last Updated: October 26, 2024

Record last verified: 2024-08

Locations

TU (1)