NCT06568497

Brief Summary

The project will consist of two studies. One study will explore the satiating properties of dairy cheese and its dairy-free substitute when consumed ad libidum, and another study will investigate their effects on postprandial glycemia. Both studies will involve healthy young adults. The secondary outcomes of these studies will be food sensory characteristics, diet-induced thermogenesis, subjective feeling of fatigue and energy, gastrointestinal comfort level, and food intake. The proposed project results will help to better understand the health properties of the cheese and its dairy-free substitute.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 1, 2024

Completed
3 days until next milestone

Study Start

First participant enrolled

August 4, 2024

Completed
19 days until next milestone

First Posted

Study publicly available on registry

August 23, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2025

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

August 29, 2025

Status Verified

August 1, 2025

Enrollment Period

1.1 years

First QC Date

August 1, 2024

Last Update Submit

August 22, 2025

Conditions

Outcome Measures

Primary Outcomes (4)

  • Blood glucose

    The concentrations of blood glucose

    0-120 minutes

  • Insulin

    The concentrations of insulin

    0-120 minutes

  • Satiety

    The components of average subjective appetite including desire to eat, hunger, fullness, and a prospective food consumption measured with 100mm visual analogue scales.

    0-120 minutes

  • Food intake

    Energy intake with an ad libitum meal at 120 minutes

    0 minutes, 120 minutes

Secondary Outcomes (4)

  • Energy and Fatigue

    0-120 minutes

  • Gastrointestinal comfort

    0-120 minutes

  • Diet-induced thermogenesis

    0-120 minutes

  • Sensory characteristics

    0 minutes, 120 minutes

Study Arms (3)

Dairy

EXPERIMENTAL

A food containing dairy cheese

Other: Food

Non-Dairy

EXPERIMENTAL

A food containing vegan alternative to cheese

Other: Food

Conrtol

EXPERIMENTAL

A control treatment in the form of food

Other: Food

Interventions

FoodOTHER

Food

ConrtolDairyNon-Dairy

Eligibility Criteria

Age19 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Young healthy adults

You may not qualify if:

  • Breakfast skipper
  • Smoker (including e-cigarettes) / cannabis consumer
  • Be underweight, overweight or obese
  • Have chronic diseases, including diabetes
  • Taking certain medication
  • Have lactose intolerance, food allergies or gastrointestinal disorders (e.g., irritable bowel syndrome, or others).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mount Saint Vincent University

Halifax, Nova Scotia, B3M 2J6, Canada

RECRUITING

MeSH Terms

Interventions

Food

Intervention Hierarchy (Ancestors)

Diet, Food, and NutritionPhysiological PhenomenaFood and Beverages

Central Study Contacts

Bohdan Luhovyy, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 1, 2024

First Posted

August 23, 2024

Study Start

August 4, 2024

Primary Completion

August 31, 2025

Study Completion

December 31, 2025

Last Updated

August 29, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Locations