NCT06558760

Brief Summary

The purpose of this study was to analyse the epidemiology, diagnostics, the type of surgical techniques and their development over time, and mortality in acute appendicitis in 68 hospitals in Germany based on routine data between 2010 and 2022.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
31,988

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2010

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
13 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

August 7, 2024

Completed
12 days until next milestone

First Posted

Study publicly available on registry

August 19, 2024

Completed
Last Updated

August 19, 2024

Status Verified

August 1, 2024

Enrollment Period

13 years

First QC Date

August 7, 2024

Last Update Submit

August 15, 2024

Conditions

Acute Appendicitis

Keywords

Acute AppendicitisType of appendectomy

Outcome Measures

Primary Outcomes (1)

  • Changes in surgical techniques over time

    Development of the use of surgical techniques (open, laparoscopic or conversion from open to laparoscopic)

    2010-2022

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with acute appendicitis in 68 hospitals in Germany collected by routine data between 2010 and 2022.

You may qualify if:

  • Acute Appendicitis

You may not qualify if:

  • Age under 18 years
  • No appendectomy performed

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Schildberg C, Weber U, Konig V, Linnartz M, Heisler S, Hafkesbrink J, Fricke M, Mantke R. Laparoscopic appendectomy as the gold standard: What role remains for open surgery, conversion, and disease severity? : An analysis of 32,000 cases with appendicitis in Germany. World J Emerg Surg. 2025 Jun 18;20(1):53. doi: 10.1186/s13017-025-00626-2.

    PMID: 40533760DERIVED

MeSH Terms

Conditions

Appendicitis

Condition Hierarchy (Ancestors)

Intraabdominal InfectionsInfectionsGastroenteritisGastrointestinal DiseasesDigestive System DiseasesCecal DiseasesIntestinal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

August 7, 2024

First Posted

August 19, 2024

Study Start

January 1, 2010

Primary Completion

December 31, 2022

Study Completion

December 31, 2022

Last Updated

August 19, 2024

Record last verified: 2024-08

Data Sharing

IPD Sharing
Will not share

Individual participant data is not available for data sharing.