NCT01816568

Brief Summary

Laparoscopic techniques have allowed surgeons to perform complicated intrabdominal surgery with minimal trauma. In numerous studies, when conventional laparoscopic appendectomy using 3 ports is compared with open appendectomy, it has advantages of reduced pain, reduced hospital stay, and enhanced cosmetic effects. Single incision laparoscopic surgery (SILS) was developed with the aim of reducing the invasiveness of conventional laparoscopy. In this study the investigators aimed to compare results of SILS appendectomy and three port conventional laparoscopic appendectomy prospectively.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2010

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2010

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2013

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 20, 2013

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 22, 2013

Completed
Last Updated

March 22, 2013

Status Verified

March 1, 2013

Enrollment Period

3 years

First QC Date

March 20, 2013

Last Update Submit

March 21, 2013

Conditions

Keywords

appendicitis, laparoscopy, single incision

Outcome Measures

Primary Outcomes (1)

  • Pain score

    Postoperative pain will be assessed according Visual analog scale from 0 (no pain) to 10 (worst pain imaginable. Postoperative six hour VAS (POSH-VAS) and postoperative first day VAS (POFD-VAS) will be recorded and compared.

    Postoperative first 24 hours

Secondary Outcomes (3)

  • Intraoperative complications

    Average of 50 minutes

  • Operating time

    Average of 50 minutes

  • Postoperative complications

    24th hour, 2nd day, 3rd day, 7th day, 1st month, 3rd month, 6th month, 1st year

Other Outcomes (1)

  • Length of hospital stay

    Average of 2 days

Study Arms (2)

Group 1

ACTIVE COMPARATOR

SILS appendectomy

Procedure: SILS appendectomy

Group 2

ACTIVE COMPARATOR

Three port laparoscopic appendectomy

Procedure: Three port laparoscopic appendectomy

Interventions

Single incision laparoscopic appendectomy will be performed

Group 1

Three port laparoscopic appendectomy will be performed

Group 2

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Required laparoscopic cholecystectomy for gallbladder disease.

You may not qualify if:

  • American Society of Anesthesiologists score (ASA) more than III,
  • Patients had prior abdominal surgery,
  • Pregnancy,
  • Ongoing peritoneal dialysis,
  • Lack of written informed consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Appendicitis

Condition Hierarchy (Ancestors)

Intraabdominal InfectionsInfectionsGastroenteritisGastrointestinal DiseasesDigestive System DiseasesCecal DiseasesIntestinal Diseases

Study Officials

  • Ugur Deveci, Assoc.Prof.

    Maltepe University School of Medicine, General Surgery Department

    PRINCIPAL INVESTIGATOR
  • Fatih Altintoprak, Assoc.Prof.

    Sakarya University School of Medicine, General Surgery Department

    PRINCIPAL INVESTIGATOR
  • Manuk Norayk Manukyan, Assoc.Prof.

    Maltepe University School of Medicine, General Surgery Department

    STUDY DIRECTOR
  • Sertan Kapakli, Assoc.Prof.

    Maltepe University School of Medicine, General Surgery Department

    PRINCIPAL INVESTIGATOR
  • Abut Kebudi, Prof.

    Maltepe University School of Medicine, General Surgery Department

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assoc.Prof.

Study Record Dates

First Submitted

March 20, 2013

First Posted

March 22, 2013

Study Start

February 1, 2010

Primary Completion

February 1, 2013

Study Completion

February 1, 2013

Last Updated

March 22, 2013

Record last verified: 2013-03