Anterior Segment Changes After Pars Plana Vitrectomy With SO Using AS-OCT

NCT06524661 | Completed DMC

• 1 other identifier: AS-OCT after PPV with SO
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate changes in ACA induced by pars plana vitrectomy with SO 1000cs injection in vitreo-retinal surgery in phakic eyes using AS-OCT and changes in the IOP preoperatively, post-operatively and post-silicone oil evacuation.

Conditions

Glaucoma

Keywords

ASOCT; Glaucoma; Silicone; vitrectomy; angle

Outcome Measures

Primary Outcomes (1)

• Assessement of the changes in anterior chamber angle after vitrectomy with silicone oil injection

  Evaluation of changes in the anterior chamber angle parameters after vitrectomy with silicone oil 1000cs injection. The measures include AOD 500, TISA 500, ACA and CCT The measuring tool is AS-OCT (anterior segment optical coherent topography)

  postoperative evaluation for 3 months duration (5 visits pre-ppv then one week, one month, three months )

Study Arms (1)

Patients with RRD who underwent pars plana vitrectomy with

AS-oct measuring the anterior chamber angle and corneal changes after pars plana vitrectomy with silicone oil 1000cs injection

Device: AS-OCT after vitrectomy

Interventions

AS-OCT after vitrectomy DEVICE

AS-OCT is a light based imaging technique of the anterior segment of the eye in this study it is used to measure the anterior chamber angle changes after pars plana vitrectomy.

Also known as: vitrectomy, silicone oil 1000cs, silicone oil evacuation

Patients with RRD who underwent pars plana vitrectomy with

Eligibility Criteria

• Age: 16 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who are phakic with rhegmatogenous retinal detachment

You may qualify if:

• Patients with rhegmatogenous retinal detachment who are going to undergo vitreoretinal surgery with silicone oil 1000cs injection as tamponade

You may not qualify if:

• Patients with history of intraocular surgery, laser therapy or intravitreal injection.
• Patients with significant corneal opacity.
• Patients with ocular diseases as retinal vein occlusion, uveitis and proliferative diabetic retinopathy.
• Patients with preexisting glaucoma or family history of glaucoma.
• Patients with nystagmus.
• Patient with tractional retinal detachment, exudative retinal detachment or intraocular foreign body.
• Patients with anterior chamber abnormalities including posterior synechia, peripheral anterior synechia, hyphaema and iris abnormalities.
• Patients with severe proliferative vitreoretinopathy grade C or more.

Sponsors & Collaborators

• Minia University: lead

Study Sites (1)

Faculty of medicine ,Minia university

Minya, 61519, Egypt

Location

Related Publications (1)

• Calik B, Ozturk M, Serdarogullari H, Elcioglu M. Evaluation of anterior segment parameters using pentacam in silicone oil-injected patients after pars plana vitrectomy. Indian J Ophthalmol. 2013 Nov;61(11):621-5. doi: 10.4103/0301-4738.123137.

  PMID: 24343592 BACKGROUND

MeSH Terms

Conditions

Glaucoma

Interventions

Vitrectomy

Condition Hierarchy (Ancestors)

Ocular Hypertension; Eye Diseases

Intervention Hierarchy (Ancestors)

Ophthalmologic Surgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Mohab Mohamed Khairy Talaat

Study Record Dates

• First Submitted: July 19, 2024
• First Posted: July 29, 2024
• Study Start: April 15, 2023
• Primary Completion: April 15, 2024
• Study Completion: April 15, 2024
• Last Updated: July 29, 2024

Record last verified: 2024-07

Locations

EG (1)