Effect of Elastic Chest Compression on Functional Exercise Capacity and Respiratory Performance in Patients With COPD

NCT06519474 | Recruiting

• 1 other identifier: 202405096RINE
• Study Type: interventional
• Target: 17
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to investigate the effects of elastic chest compression on functional exercise capacity and respiratory performance of patients with COPD. The main questions it aims to answer are: Is there difference in functional exercise capacity and respiratory performance without or with the use of elastic upper chest compression? Is there difference in functional exercise capacity and respiratory performance between the use of elastic upper chest compression and elastic lower chest compression? Participants will: Be evaluated under three conditions on three different days: without elastic compression, with upper chest compression, and with lower chest compression, with the order of compression application randomly assigned. The functional capacity and respiratory muscle performance of all patients will be evaluated. The days for evaluation will be at least three days apart from each other.

Conditions

COPD; Hyperinflation

Keywords

chronic obstructive pulmonary disease; dynamic hyperinflation; elastic chest compression; functional exercise capacity; respiratory performance

Outcome Measures

Primary Outcomes (3)

• Functional exercise capacity

  6 minute walk test measured in meters

  up to 3 weeks

• Respiratory muscle performance

  Maximum inspiratory (MIP) and expiratory pressures (MEP) in mmH2O

  up to 3 weeks

• Respiratory flow performance

  peak inspiratory (PIFR) and expiratory flows (PEFR) in liter per minute

  up to 3 weeks

Study Arms (2)

Upper chest compression

EXPERIMENTAL

The Theraband will be wrapped around the subject's upper chest with upper edge of the Theraband aligned to the 3rd intercostal space and fastened on the upper rib cage for the upper chest compression arm.

Device: Theraband chest compression

Lower chest compression

EXPERIMENTAL

The Theraband will be wrapped around the subject's lower rib cage by placing the central horizontal part of the Theraband at the xiphoid process of the sternum for the lower chest compression arm.

Device: Theraband chest compression

Interventions

Theraband chest compression DEVICE

Chest compression applicated via a Red Theraband over the upper or lower chest region

Lower chest compression; Upper chest compression

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• at least 20 years old
• has a clinical diagnosis of COPD without infection or acute exacerbation in the previous four weeks
• is capable of cooperating with the required tests and measurements of the study

You may not qualify if:

• has any clinical diagnosis that could affect test outcomes (e.g., neuromyopathy)
• has experienced unstable angina or an acute myocardial infarction within the last month
• has adjusted COPD related medication within the last month
• a Mini-Mental State Examination (MMSE) score below 24

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital Hsinchu Branch

Hsinchu, Taiwan

RECRUITING

Related Publications (23)

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  BACKGROUND

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  BACKGROUND

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  PMID: 12796152 BACKGROUND

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• Ichiba T, Miyagawa T, Kera T, Tsuda T. Effect of manual chest wall compression in participants with chronic obstructive pulmonary disease. J Phys Ther Sci. 2018 Nov;30(11):1349-1354. doi: 10.1589/jpts.30.1349. Epub 2018 Nov 6.

  PMID: 30464362 BACKGROUND

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MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Yi Chun Chen

CONTACT

+886-5326151; G00997@hch.gov.tw

Yi Chun Chen

CONTACT

+886-961320509; jenchein@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 14, 2024
• First Posted: July 25, 2024
• Study Start: July 10, 2024
• Primary Completion (Estimated): May 31, 2027
• Study Completion (Estimated): May 31, 2027
• Last Updated: July 25, 2024

Record last verified: 2024-07

Locations

TW (1)