Functional Status in COPD Patients After Exercise Rehabilitation Program

NCT06142266 | Unknown

• 1 other identifier: COPD&Exercise rehabilitation
• Study Type: interventional
• Target: 120
• Locations: 0 countries
• Sites: N/A

Brief Summary

To evaluate the effectiveness of the exercise program in improving physical fitness and exercise capacity in COPD patients like walking distance, muscle strength, endurance will be measured before and after the program. To assess whether the program helps reduce COPD symptoms like shortness of breath and fatigue during daily activities. Quality of life questionnaires will be used.

Conditions

Copd

Outcome Measures

Primary Outcomes (1)

• Improvement in exercise capacity

  Asess by Change in 6-minute walk distant

  baseline

Secondary Outcomes (1)

• Health related quilt of life

  baseline

Study Arms (2)

Intervention group

ACTIVE COMPARATOR

The intervention group (n=60) will undergo a 12-week pulmonary rehabilitation program. This program will consist of twice-weekly supervised exercise sessions, including aerobic training and resistance exercises targeting the lower limbs.

Other: Exercise rehabilitation program

Control group

ACTIVE COMPARATOR

The control group (n=60) will receive usual medical care according to guidelines, which may include bronchodilator/anti-inflammatory therapy but no formal pulmonary rehabilitation.

Other: Exercise rehabilitation program

Interventions

Exercise rehabilitation program OTHER

This program will consist of twice-weekly supervised exercise sessions, including aerobic training and resistance exercises targeting the lower limbs for 12-week

Control group; Intervention group

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of moderate-severe chronic obstructive pulmonary disease (COPD) based on spirometry results and clinical assessment.
• Age between 40 and 75 years. Stable disease status, defined as no exacerbations requiring admission to respiratory intensive care unit
• Willingness and ability to participate in a 12-week pulmonary rehabilitation program.

You may not qualify if:

• Presence of significant comorbidities or medical conditions that may interfere with participation in the pulmonary rehabilitation program (e.g., severe cardiovascular disease, musculoskeletal disorders, uncontrolled hypertension).
• Inability to perform the required exercise activities due to physical limitations or disabilities.
• Cognitive impairment

Sponsors & Collaborators

• Assiut University: lead

Related Publications (2)

• Gloeckl R, Schneeberger T, Jarosch I, Kenn K. Pulmonary Rehabilitation and Exercise Training in Chronic Obstructive Pulmonary Disease. Dtsch Arztebl Int. 2018 Feb 23;115(8):117-123. doi: 10.3238/arztebl.2018.0117.

  PMID: 29526182 BACKGROUND

• Rutkowski S, Rutkowska A, Kiper P, Jastrzebski D, Racheniuk H, Turolla A, Szczegielniak J, Casaburi R. Virtual Reality Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial. Int J Chron Obstruct Pulmon Dis. 2020 Jan 13;15:117-124. doi: 10.2147/COPD.S223592. eCollection 2020.

  PMID: 32021150 BACKGROUND

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Heba fahmy, MD

  Assiut University

  STUDY CHAIR

Central Study Contacts

Hend saleh, MD

CONTACT

01098988712; hend.m.saleh@gmail.com

Aliae Hussein, professor

CONTACT

01222302352; Aliaehussein@aun.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants will be randomly allocated to either the intervention or control group in a 1:1 ratio using computer-generated randomization
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecture of chest diseases

Model Details: randomized controlled trial conducted at Chest Department at Assiut University Hospital

Study Record Dates

• First Submitted: November 16, 2023
• First Posted: November 21, 2023
• Study Start: January 1, 2024
• Primary Completion: May 1, 2025
• Study Completion: July 1, 2025
• Last Updated: November 21, 2023

Record last verified: 2023-11