Effects of Exercise Training with Blood Flow Restriction

NCT06507501 | Completed

• 1 other identifier: Onur1
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, it was aimed to compare the effects of low load blood flow restriction exercise (LL-BFRE) training versus high load resistance exercise (HL-RE) training in healthy young individuals on the parameters of lower extremity muscle strength, dynamic and static postural balance, functional performance and cognitive performance.

Conditions

Healthy

Keywords

Blood Flow Restriction Exercise Training; Muscle Strength; Balance; Functional Performance; Cognitive Performance

Outcome Measures

Primary Outcomes (3)

• Muscle Strength

  Knee extansor and flexor muscle strength will be measured by using Hoggan Scientific; MicroFET2 brand hand-held dynamometer.

  Baseline to 6 weeks after exercise training

• Dynamic Balance

  Dynamic balance will be assessed by using Y-Balance Test Lower Extremity.

  Baseline to 6 weeks after exercise training

• Static Balance

  Static balance will be assessed by using Single Leg Stance Test with eyes open and closed.

  Baseline to 6 weeks after exercise training

Secondary Outcomes (4)

• Funtional Performance

  Baseline to 6 weeks after exercise training

• Funtional Performance

  Baseline to 6 weeks after exercise training

• Cognitive Performance

  Baseline to 6 weeks after exercise training

• Cognitive Performance

  Baseline to 6 weeks after exercise training

Other Outcomes (2)

• Sociodemographic Information

  Baseline

• Physical Assessment

  Baseline

Study Arms (2)

Blood Flow Restriction Exercise Training (BFRT)

EXPERIMENTAL

Exercises will be performed under the supervision of a researcher physiotherapist, at low intensity and progressively, under blood flow restriction for 6 weeks, 2 days a week, for a total of 12 exercise sessions. The 1 MT method will be used to determine the amount of resistance in strengthening exercises. Blood flow restriction will be made by wearing a pneumatic tourniquet from the proximal thigh, within a safe pressure range specific to each individual. Blood flow restriction United States Food and Drug Administration Using the (FDA) approved H+Cuff device, it will be applied for 20 minutes, with a 1-minute break between exercises. The cuff pressure will be maintained during the rest period, and after the application, individuals will rest for 15 minutes to ensure reperfusion and other exercises will continue.

Other: Low Load Blood Flow Restriction Exercise Training (LL-BFRE)

Conventional Exercise Training

EXPERIMENTAL

Participants who will be included in the conventional exercise group will apply the same exercise program as the participants in the blood flow-restricted exercise group, without blood flow restriction, for 6 weeks, 2 days a week, in a total of 12 sessions, at medium-high intensity.

Other: High Load Resistive Exercise Training (HL-RE)

Interventions

Low Load Blood Flow Restriction Exercise Training (LL-BFRE) OTHER

Blood Flow Restriction exercise training, also known as occlusion training or KAATSU training, is a contemporary exercise training method based on partially restricting arterial and venous blood flow for short periods.

Blood Flow Restriction Exercise Training (BFRT)

High Load Resistive Exercise Training (HL-RE) OTHER

HL-RE is a conventional, well known exercise method to enhance muscle strength and improve physical performance. It's performed by using resistance bands or weights applying on the extremity.

Conventional Exercise Training

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Volunteering to participate in the study,
• Being between the ages of 18-30.

You may not qualify if:

• Presence of any painful condition or pathology involving the lower extremity and lumbar spine and the presence of a surgical history,
• Presence of serious malalignment and deformity affecting the lower extremity,
• Presence of neuromuscular and metabolic disease,
• Presence of any disease affecting lower extremity circulation,
• Having a history of deep vein thrombosis and the presence of peripheral vascular disease,
• Presence of endothelial dysfunction (ED) and any disease that may cause ED,
• Presence of active infection, cancer and having received radiotherapy / chemotherapy,
• Continuous use of anticoagulant medication,
• Having had COVID-19 in the last 3 months or having long COVID syndrome,
• Presence of a cognitive or mental disorder that would disability to participate in the study,
• Disruption of exercise program 3 times in a row

Sponsors & Collaborators

• Atlas University: lead

Study Sites (1)

Onur Turan

Istanbul, Kağıthane, 34408, Turkey (Türkiye)

Location

Study Officials

• Onur Turan, Bachelor's

  Atlas University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assisstant

Study Record Dates

• First Submitted: June 27, 2024
• First Posted: July 18, 2024
• Study Start: April 15, 2024
• Primary Completion: February 6, 2025
• Study Completion: February 6, 2025
• Last Updated: February 10, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)