Effect of Aerobic Exercise Versus Resistance Exercise on Bone Density in Postmenopausal Diabetic Women

NCT06505044 | Completed

• 1 other identifier: Physical Therapy
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Osteoporosis is a significant public health issue, especially among postmenopausal women with diabetes, and its prevalence is increasing. This trial aims to determine the influence of moderate intensity aerobic exercise vs resistance exercise on bone mineral density among postmenopausal diabetic women.

Conditions

Osteoporosis

Outcome Measures

Primary Outcomes (1)

• The bone mineral density (BMD)

  • Dual Energy X-ray Absorptiometry (DEXA). It was used to measure the bone mineral density (BMD) of the lumbar spine for each woman in both groups before and after the study.

  3 months

Study Arms (2)

Group (A)

EXPERIMENTAL

25 patients receive aerobic exercise attended the program of walking on a treadmill machine for eight weeks according to specific parameters, in addition to their usual daily calcium intake.

Procedure: aerobic exercise; Procedure: resistance exercise

Group (B)

ACTIVE COMPARATOR

25 patients receive resisted exercise in addition to their usual daily calcium intake for 12 weeks.

Procedure: aerobic exercise; Procedure: resistance exercise

Interventions

aerobic exercise PROCEDURE

aerobic exercise. * Intensity: according to heart rate (60-75% of maximum heart rate) MHR=220-age. * Heart rate: determined by the sensor of a treadmill. * Duration: 40-50 min per session. Each session consisted of 5-10 minutes of warming up exercise on a treadmill without increasing speed or intensity and the same for the cooling down phase. There was 30 minutes of conditioning exercise including increasing the treadmill speed till reaching (60-75%) of the maximum heart rate. * Frequency: 3 times/week for 12 weeks in addition to their usual daily calcium intake.

Group (A); Group (B)

resistance exercise PROCEDURE

resisted exercise program for 12 weeks

Group (A); Group (B)

Eligibility Criteria

• Age: 50 Years - 60 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Fifty women postmenopausal obese women
• (BMI) 30 -35 kg/m2
• their age ranges from 50 to 60 years old and
• complain of diabetic type 2 for 10 years ago.

You may not qualify if:

• women with renal or liver disease,
• cardiac or chest disease psychological problems,
• cognitive problems are excluded from the study.
• Any women who have therapeutic problems that will interfere with performing exercise or affection BMD will be excluded from this study.

Sponsors & Collaborators

• Deraya University: lead

Study Sites (1)

Soad A. Mohamad

Minya, 05673, Egypt

Location

MeSH Terms

Conditions

Osteoporosis

Interventions

Exercise; Resistance Training

Condition Hierarchy (Ancestors)

Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Double-blind masking the patient was not be informed about the training group or the other group; they will be evaluated and trained at different places and times.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 2, 2024
• First Posted: July 17, 2024
• Study Start: March 10, 2024
• Primary Completion: June 22, 2024
• Study Completion: August 1, 2024
• Last Updated: September 23, 2025

Record last verified: 2025-09

Locations

EG (1)