NCT06494670

Brief Summary

The goal of this observational study is to explore the prevalence trends of 11 site-specific musculoskeletal pain from 1999 to 2018. The main question it aims to answer is: Does the prevalence of musculoskeletal pain among U.S. adults changed from 1999 to 2018? What are the trends? Participants will answer survey questions about their musculoskeletal pain on the past three months.

Trial Health

53
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
565,219

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 1999

Longer than P75 for all trials

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1999

Completed
25.5 years until next milestone

First Submitted

Initial submission to the registry

July 2, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 10, 2024

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

July 16, 2024

Status Verified

July 1, 2024

Enrollment Period

26 years

First QC Date

July 2, 2024

Last Update Submit

July 13, 2024

Conditions

Keywords

Musculoskeletal painPrevalenceAge-period-cohort effects

Outcome Measures

Primary Outcomes (1)

  • Musculoskeletal pain

    Participants aged 18 years or older were asked the following questions: "During the past three months, did you have \[neck pain, low back pain, or jaw/front of ear pain\]?" and "During the past 30 days, did you have joint pain?". Participants who answered affirmatively to joint pain were then asked to report the site of their joint pain. The options included shoulder, elbow, hip, wrist, knee, ankle, toes, and Participants aged 18 years or older were asked the following questions: "During the past three months, did you have \[neck pain, low back pain, or jaw/front of ear pain\]?" and "During the past 30 days, did you have joint pain?". Participants who answered affirmatively to joint pain were then asked to report the site of their joint pain. The included shoulder, elbow, hip, wrist, knee, ankle, toes, and fingers/thumb.

    1999-2018

Interventions

This study was a cross-sectional study with no intervention for participants

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The National Health Interview Survey (NHIS) is a national survey conducted by the U.S. Census Bureau on behalf of the National Center for Health Statistics (NCHS). NHIS is the principal source of information on the health of the civilian noninstitutionalized population of the United States. The target population for the NHIS is the civilian noninstitutionalized population residing within the 50 states and the District of Columbia at the time of the interview. NCHS is bound by law to protect participant data, following rigorous privacy standards that have protected every NHIS participant since the first survey in 1957. Base on NHIS data, we included adults aged 18 years and older who were interviewed in a survey wave between 1999 and 2018 in this study. From the total unweighted sample of 603,140 respondents, we excluded 37,921 due to missing data on independent variables or musculoskeletal pain, resulting in an analytic sample size of 565,219.

You may qualify if:

  • Residents of households and noninstitutional group quarters (e.g., homeless shelters, rooming houses, and group homes);
  • Persons residing temporarily in student dormitories or temporary housing are sampled within the households that they reside in permanently.

You may not qualify if:

  • Persons with no fixed household address (e.g., homeless and/or transient persons not residing in shelters);
  • Active duty military personnel and civilians living on military bases, persons in long-term care institutions (e.g., nursing homes for the elderly, hospitals for the chronically ill or physically or intellectually disabled, and wards for abused or neglected children);
  • Persons in correctional facilities (e.g., prisons or jails, juvenile detention centers, and halfway houses), and U.S. nationals living in foreign countries.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Musculoskeletal PainNeck PainLow Back PainArthralgiaShoulder Pain

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBack PainJoint Diseases

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Investigator

Study Record Dates

First Submitted

July 2, 2024

First Posted

July 10, 2024

Study Start

January 1, 1999

Primary Completion

December 31, 2024

Study Completion

December 31, 2024

Last Updated

July 16, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will share

The data utilized in this study was sourced from the National Health Interview Survey (NHIS), with the NHIS protocol having obtained approval from the NCHS Research Ethics Review Board. Additionally, written consent was secured from all participants prior to data collection. It should be noted that all data shared have been fully anonymized and do not contain any personal identifying information about the participants.

Shared Documents
ANALYTIC CODE
Time Frame
NHIS database 1999-2018 data
Access Criteria
The data used in this study was obtained from the publicly available National Health Interview Survey (NHIS) database. The NHIS is a publicly accessible resource, and researchers can freely access and use the data for their studies.
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