Uterine Position and Pain and Central Sensitization Parameters in Women With Chronic Low Back Pain

NCT07549009 | Completed

• 1 other identifier: istftreah155
• Study Type: observational
• Target: 128
• Locations: 1 country
• Sites: 1

Brief Summary

Female patients aged 18-75 years with chronic low back pain (lasting at least 3 months) will be included in the study. Demographic data including age, height, weight, educational status, marital status, and comorbidities will be recorded. In addition, clinical characteristics such as pain duration, pain distribution, analgesic use, and concomitant musculoskeletal disorders will be assessed. Uterine position will be evaluated based on pelvic magnetic resonance imaging (MRI) or pelvic ultrasonography reports obtained within the last year. According to uterine position, participants will be divided into two groups: posteriorly positioned uterus (retroverted and/or retroflexed uterus) and anteriorly positioned uterus (anteverted uterus). Pain severity will be assessed using the Visual Analog Scale (VAS), and pain duration will be recorded in months. Pressure pain threshold measurements will be performed using an algometer at bilateral lumbar paraspinal muscles, gluteal regions, and the mid-deltoid muscle as a remote control point. Central sensitization will be assessed using the Central Sensitization Inventory (CSI), and pain catastrophizing will be evaluated using the Pain Catastrophizing Scale (PCS). All assessments will be conducted through face-to-face interviews. No additional laboratory tests, interventional procedures, or treatments will be applied to the participants within the scope of the study. Validated Turkish versions of all scales will be used. The collected data will be analyzed to investigate the relationship between uterine position and pressure pain threshold, central sensitization, and pain catastrophizing levels in women with chronic low back pain.

Conditions

Low Back Pain

Outcome Measures

Primary Outcomes (1)

• Pressure Pain Threshold (PPT)

  Pressure pain threshold (kg/cm²) will be measured using an algometer at bilateral lumbar paraspinal muscles, gluteal regions, and the mid-deltoid muscle as a remote control point. Lower values indicate increased pain sensitivity.

  Baseline

Secondary Outcomes (3)

• Visual Analog Scale (VAS)

  Baseline

• Central Sensitization Inventory (CSI)

  Baseline

• Pain Catastrophizing Scale (PCS)

  Baseline

Study Arms (2)

Group 1

Retrovert uterus

Other: No intervention

Group 2

Antevert uterus

Other: No intervention

Interventions

No intervention OTHER

No intervention

Group 1; Group 2

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: female
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population will consist of female patients aged 18-75 years with chronic low back pain (lasting at least 3 months) who are admitted to the Physical Medicine and Rehabilitation outpatient clinics of Bakırköy Dr. Sadi Konuk Training and Research Hospital and Istanbul Physical Therapy and Rehabilitation Training and Research Hospital during the study period. Participants will be recruited consecutively. Only patients with available pelvic MRI and/or ultrasonography within the last year allowing classification of uterine position will be included. All participants will be medically stable and able to complete the study assessments.

You may qualify if:

• Female, aged 18-75 years Presence of chronic low back pain (lasting at least 3 months) Availability of pelvic MRI and/or pelvic ultrasonography within the last year with assessable uterine position (anteverted, retroverted, retroflexed) Ability to read and understand Turkish and complete questionnaires Willingness to participate

You may not qualify if:

• Pregnancy or childbirth within the last 6 months (postpartum period) History of lumbar spine surgery, vertebral fracture, or spinal malignancy Presence of inflammatory rheumatic disease (e.g., ankylosing spondylitis), severe neurological disease, or systemic disease affecting low back pain Severe cognitive impairment, communication problems, or major psychiatric disorder preventing participation Absence of pelvic imaging or inability to classify uterine position

Sponsors & Collaborators

• Istanbul Physical Medicine Rehabilitation Training and Research Hospital: lead

Study Sites (1)

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Istanbul, 34192, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 18, 2026
• First Posted: April 23, 2026
• Study Start: March 16, 2026
• Primary Completion: April 16, 2026
• Study Completion: April 16, 2026
• Last Updated: April 23, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)