NCT06464120

Brief Summary

With the advancement of sports science, Post-Activation Potentiation (PAP) has become a focal point of research, garnering significant attention for its underlying physiological mechanisms. Current studies suggest three primary mechanisms: 1) phosphorylation of myosin regulatory light chains (RLCs); 2) increased recruitment of high-threshold motor units; and 3) a reduction in sarcomere length heterogeneity within muscle fibers due to pre-stimulation (Liu \& Li, 2017). These mechanisms collectively contribute to an effect known as Post-Activation Performance Enhancement (PAPE), which significantly enhances muscle strength and explosiveness shortly after activation (Blazevich \& Babault, 2019). During the activation process of motor units with increasing loads, low-threshold motor units are recruited first, followed by high-threshold motor units. As the load increases, the root mean square (RMS) value increases linearly, further promoting the overlap of motor unit potentials and the rise in RMS values. This overlap in activation timing among adjacent motor units results in greater overall muscle force output (Liu, 2008; Tian, 2009). The significance of this lies in the fact that as the degree of muscle activation increases, especially under incremental loads, the muscle's ability to adapt to subsequent strength or explosive tasks may be enhanced. In competitive sports, optimizing the relationship between warm-up and performance is crucial. Research indicates that the duration of PAPE varies with individual differences, training type, intensity, and recovery intervals. The characteristics of the PAPE effect also differ. Additionally, following constant loads, the enhancement and decay rates of performance in PAPE show varying rates at different times, and these rates do not exhibit a symmetrical linear change in absolute value (Liang, M 2020; Guo, W et al. 2018; Liu, R and Li, Q. 2017). The competition pace in sports demands precise modulation of performance enhancement rates after activation, and athletes can leverage these characteristics by selecting appropriate loading forms to trigger PAPE at critical moments in competition. To explore the enhancement or decay rates of performance over different time domains, our research team designed a protocol consisting of incremental loads.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 12, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 18, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

July 18, 2024

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2024

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 25, 2024

Completed
Last Updated

July 29, 2024

Status Verified

July 1, 2024

Enrollment Period

2 days

First QC Date

June 12, 2024

Last Update Submit

July 26, 2024

Conditions

Keywords

Post-activation performance enhancementstrength trainingtake-off heightround reaction forcepeak power

Outcome Measures

Primary Outcomes (3)

  • Ground reaction force

    The ground reaction force of the lower limbs during the half squat jump was measured by the force platform.

    30 seconds, 3 minutes, 6 minutes, 9 minutes, 12 minutes after intervention and before intervention

  • Peak Power

    Athletes measured the peak power of the lower limbs in the half squat jump using a force platform

    30 seconds, 3 minutes, 6 minutes, 9 minutes, 12 minutes after intervention and before intervention

  • Height

    The athlete uses a 3D motion capture device to measure the height of the highest point of the half squat jump

    30 seconds, 3 minutes, 6 minutes, 9 minutes, 12 minutes after intervention and before intervention

Study Arms (2)

Incremental load training group

EXPERIMENTAL

This training plan is a single training,The load intensity of strength training for athletes :(5,4,3)RM×1 time ×1set for half squat jump

Other: Increasing load strength training

Constant load training group

EXPERIMENTAL

This training plan is a single training,This training plan is a single training,Constant load of strength training for athletes :90%1RM×3 time ×1set for half squat jump

Other: Constant load strength training

Interventions

The Smith machine was used to intervene with athletes by employing an incremental load approach.

Incremental load training group

The Smith machine was used to intervene with athletes by employing a constant load approach.

Constant load training group

Eligibility Criteria

Age19 Years - 24 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may not qualify if:

  • (1) Individuals with a history of lower limb joint injuries; (2) Individuals with cardiovascular diseases, skin allergies, hernia, or any other contraindications; (3) Individuals unwilling to participate in the experiment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

RongWenchao

Qinhuangdao, Hebei, 066004, China

Location

Study Officials

  • wenchao Rong, phd

    University Putra Malaysia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Participant, Investigator, Outcomes Assessor
Purpose
BASIC SCIENCE
Intervention Model
SEQUENTIAL
Model Details: The experimental group was randomly assigned to receive strength training with increasing loads for post-activation enhancement intervention, while the control group received strength training with constant loads.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Study Principal Investigator

Study Record Dates

First Submitted

June 12, 2024

First Posted

June 18, 2024

Study Start

July 18, 2024

Primary Completion

July 20, 2024

Study Completion

July 25, 2024

Last Updated

July 29, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

I won't share it, until I published this paper

Locations