NCT06458920

Brief Summary

The goal of this project is to test whether regulating emotions with help from a friend is more effective and long-lasting in adolescents than regulating alone, and to characterize age-related differences in the neural mechanisms supporting social versus cognitive emotion regulation. Participants will complete a psychology experiment while undergoing fMRI scanning.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
1mo left

Started Oct 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress98%
Oct 2022Jun 2026

Study Start

First participant enrolled

October 5, 2022

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

June 7, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 14, 2024

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Last Updated

June 24, 2025

Status Verified

June 1, 2025

Enrollment Period

3.7 years

First QC Date

June 7, 2024

Last Update Submit

June 18, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Negative affect

    Participant's self-reported negative affect on 1-4 scale (1=not bad at all, 4=very bad) during experiment

    1 day

Study Arms (2)

Social regulation

EXPERIMENTAL

Participants will regulate emotion with the help of a friend

Behavioral: Social regulation

Cognitive regulation

EXPERIMENTAL

Participants will regulate emotion on their own

Behavioral: Cognitive regulation

Interventions

Participants will regulate emotion with the help of a friend

Social regulation

Participants will regulate emotion on their own

Cognitive regulation

Eligibility Criteria

Age13 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Adolescent participants must be 13-15 year of age
  • Adult participants must be 20-25 years of age
  • Proficient in English

You may not qualify if:

  • Auditory, visual or cognitive impairment
  • Any health conditions that are contraindicated for MRI

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of California, Los Angeles

Los Angeles, California, 90095, United States

RECRUITING

MeSH Terms

Conditions

Emotional Regulation

Interventions

Social Control, Formal

Condition Hierarchy (Ancestors)

Self-ControlSocial BehaviorBehavior

Intervention Hierarchy (Ancestors)

Health Care Economics and Organizations

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Model Details: During one MRI scan, participants will spend part of the time regulating emotion on their own and part of the time regulating emotion with the help of a friend
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

June 7, 2024

First Posted

June 14, 2024

Study Start

October 5, 2022

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

June 1, 2026

Last Updated

June 24, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will share

Deidentified participant data including age, gender and negative affect

Shared Documents
STUDY PROTOCOL, SAP, ANALYTIC CODE
Time Frame
12 months from study completion
Access Criteria
Deidentified data will be posted on Open Science Framework

Locations