Short-term Circuit Training on Muscle Mass and Quality of Life in Sedentary Postmenopausal Women

NCT06445842 | Recruiting

• 1 other identifier: 5230490
• Study Type: interventional
• Target: 46
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this graduate student research study is to provide healthcare professionals with evidence of the potential of circuit strength training in improving the physical and psychosocial well-being of postmenopausal women.

Conditions

Postmenopausal

Keywords

postmenopausal; balance

Outcome Measures

Primary Outcomes (2)

• sleep quality

  The Pittsburgh Sleep Quality Index will be used to measure any trouble sleeping.

  change between baseline and eight weeks

• IL-6 Biomarker

  Inflammatory biomarker IL-6 will be tested using a blood draw.

  change between baseline and eight weeks

Study Arms (2)

Exercise Group

EXPERIMENTAL

This group will perform exercises three times a week for eight weeks, with each session lasting approximately 45 minutes.

Other: Exercise

Non-Exercise Group

ACTIVE COMPARATOR

This group will maintain their sedentary lifestyle and will not make any changes to their diet or activity levels during this period

Other: No exercise

Interventions

Exercise OTHER

The protocol involves a 10-minute warm-up and cool-down session, followed by two sets of high-intensity circuit training exercises (bench press, squats, overhead press, calf raising, barbell row, deadlifts) that last 12 minutes each (6 stations×2sets). There will be a 3-minute break between the exercise sets. The heart rate required during the exercise will be between 70-90% of their maximum capacity and a pre-scale rate of 7.5. The intensity of the exercise will be progressive each two weeks, commencing at 50% of their one rep max and increasing to 80% in their last week. During the initial phase, participants will be required to complete eight reps for each exercise. We will encourage them to increase their intensity level every two weeks.

Exercise Group

No exercise OTHER

This group will need to maintain their sedentary lifestyle without changing their activity levels or diet

Non-Exercise Group

Eligibility Criteria

• Age: 50 Years - 75 Years
• Gender Eligibility Details: Self-reported postmenopausal status
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Females aged between 50 and 75 years.
• Self-reported postmenopausal status (i.e., cessation of menstruation for a minimum of 12 months).
• Physically capable of participating in an exercise intervention.
• No engagement in structured resistance or aerobic training programs in the six months preceding the study.

You may not qualify if:

• Classification as moderate and highly active on the International Physical Activity Questionnaire (IPAQ) (600-3000 MET-minutes/week for "moderate" and higher than 3000 MET-minutes/week for "high" score)
• Diagnosis of any health condition that constitutes a contraindication to physical exercise (e.g., significant cardiovascular disease, orthopedic or neuromuscular restrictions impacting exercise performance or safety).
• Regular use of medication with the potential to affect study outcomes (e.g., corticosteroids, immunosuppressants).

Sponsors & Collaborators

• Loma Linda University: lead

Study Sites (1)

Loma Linda University

Loma Linda, California, 92354, United States

RECRUITING

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Everett Lohman, DSc

  Loma Linda University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Everett Lohman, Dsc

CONTACT

(909) 558-1000; elohman@llu.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 31, 2024
• First Posted: June 6, 2024
• Study Start: May 29, 2024
• Primary Completion: May 1, 2026
• Study Completion (Estimated): May 31, 2026
• Last Updated: February 4, 2026

Record last verified: 2026-02

Locations

US (1)