Patients' Positions on Analgesic Efficacy of ESPB

NCT06441071 | Recruiting

• 1 other identifier: KY20240419-03
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if patients remaining different positions for 30min after receiving ultrasound-guided erector spinae plane block influenced the postoperative analgesia. The main questions it aims to answer are: Does patients maintain prone position or lateral position for 30 min after ESPB provided superior analgesic effect than in the supine position? Is ESPB not inferior to PVB considering postoperative opioid consumption ? Researchers will compare the opioid consumption 24h postoperatively among the patients remaining supine, lateral, prone position after ESPB and PVB to see if patients maintaining lateral or prone position provided excellent postoperative analgesia. Participants will: Maintaining supine lateral or prone position for 30 min following ESPB or receiving PVB. Receiving postoperative NRS and QoR assessment

Conditions

Erector Spinae Plane Block

Keywords

Paravertebral thoracic block; Clinical application; Perioperative analgesia; Erector spinae plane block

Outcome Measures

Primary Outcomes (1)

• Postoperative Oxycodone dosage

  Cumulative oxycodone dosage 24 hour postoperatively

  24 hour postoperatively

Secondary Outcomes (8)

• Loss to cold sensation of skin

  30 minute after block

• NRS(Numeric Rating Scales) score

  Postoperative 1, 3, 6, 12, 24, 48 hour

• Adverse reaction

  24, 48 hour postoperatively

• QoR-15 score(Quality of Recovery,QoR)

  Day 1 and 2 postoperatively

• Opioid dosage

  1, 3, 6, 12, 24, 48 hour postoperatively

Study Arms (4)

Group S

EXPERIMENTAL

After completion of the erector spinae plane block, patients in group S remained in the supine position for 30 minutes.

Procedure: position

Group L

EXPERIMENTAL

After completion of the erector spinae plane block, patients in group L remained in the lateral position for 30 minutes.

Procedure: position

Group P

EXPERIMENTAL

After completion of the erector spinae plane block, patients in group P remained in the prone position for 30 minutes.

Procedure: position

Group C

OTHER

After completion of the paravertebral block, patients in group C remained in the supine position for 30 minutes.

Procedure: position

Interventions

position PROCEDURE

Patients undergoing Video-assisted Thoracoscopic Surgery were selected for the study, and nerve block was performed before surgery, followed by holding different positions for 30 min, after which the effect of the block was measured.

Group C; Group L; Group P; Group S

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients undergoing Video-assisted Thoracoscopic Surgery under elective general anaesthesia were selected, regardless of sex, age 18-80 years, BMI: 18-30 kg.m-2, ASA classification I-III.

You may not qualify if:

• Allergy to the study drug or allergy to local anaesthetics;
• History of opioid abuse;
• Previous nerve block puncture with puncture site infection；
• Peripheral neuropathy；
• Coagulation abnormalities, defined as prothrombin time or partial activation time prothrombin time exceeding standard values or international normalised ratio (INR) ≥ 1.4, or platelet count ≤ 70 x 109 L-1.

Sponsors & Collaborators

• Nanjing First Hospital, Nanjing Medical University: lead

Study Sites (1)

Nanjing First Hospital

Nanjing, Jiangsu, 210006, China

RECRUITING

MeSH Terms

Interventions

Patient Positioning

Intervention Hierarchy (Ancestors)

Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Study Officials

• Tao Shan

  Nanjing First Hospital, Nanjing Medical University

  STUDY DIRECTOR

Central Study Contacts

Xinyi Bu, MD

CONTACT

+86 18360868010; 1037031075@qq.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 8, 2024
• First Posted: June 4, 2024
• Study Start: June 14, 2024
• Primary Completion: April 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: July 21, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)