External Oblique Intercostal Plane Block Versus Thoracic Paravertebral Block for Post Thoracotomy Pain

NCT06431880 | Completed

• 1 other identifier: 36246PR638/4/24
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to compare the effectiveness of analgesia achieved by external oblique intercostal plane block (EOIPB)and thoracic paravertebral block (TPVB) for postoperative pain management in patients undergoing open thoracotomy.

Conditions

External Oblique Intercostal Plane Block; Thoracic Paravertebral Block; Post Thoracotomy Pain

Outcome Measures

Primary Outcomes (1)

• Total morphine consumption

  Rescue analgesia of morphine will be given as 2 mg bolus if the numeric rating scale (NRS) \> 3 to be repeated after 30 min if pain persists until the numeric rating scale \< 4. numeric rating scale will be assessed at 0, 4, 8, 12, 18 and 24h postoperatively.

  24 hours postoperatively

Secondary Outcomes (6)

• Intraoperative fentanyl consumption

  Intraoperative

• Mean arterial pressure

  Till the end of surgery

• Heart rate

  Till the end of surgery

• Time to the 1st rescue analgesia

  24 hours postoperatively

• Degree of pain

  24 hours postoperatively

Study Arms (2)

External oblique intercostal plane block

EXPERIMENTAL

Patients will receive external oblique intercostal plane block.

Other: External oblique intercostal plane block

Thoracic paravertebral block

EXPERIMENTAL

Patients will receive thoracic paravertebral block.

Other: Thoracic paravertebral block

Interventions

External oblique intercostal plane block OTHER

Patients will receive external oblique intercostal plane block

External oblique intercostal plane block

Thoracic paravertebral block OTHER

Patients will receive thoracic paravertebral block

Thoracic paravertebral block

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-III.
• Scheduled for open thoracotomy

You may not qualify if:

• Patients with neurological or intellectual disability.
• Infection at the injection site.
• Opioid addiction.
• Allergic reaction to local anesthetics.
• Coagulation abnormalities.
• Drug abuse.
• Pregnancy.
• Severe liver and/or renal failure.
• Uncontrolled hypertension.
• Severe cardiovascular problems.
• Diabetes mellitus.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University Hospitals

Tanta, El-Gharbia Governorate, Egypt, 31527, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: May 16, 2024
• First Posted: May 29, 2024
• Study Start: May 30, 2024
• Primary Completion: June 1, 2025
• Study Completion: June 1, 2025
• Last Updated: August 19, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)