Comparison of Aerobic and Resistance Training on Exercise Capacity, Depression and Quality of Life in Hypothyroidism.

NCT06377826 | Recruiting

• 1 other identifier: RCRAHS-ISB/REC/MS-PT/01813
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

the study will show the effects of aerobic and resistance training on exercise capacity, depression and quality of life in patients with hypothyroidism. The evaluation of TSH level before and after the exercise sessions will provide valuable data.

Conditions

Comparison of Aerobic Exercise and Resistance Training

Outcome Measures

Primary Outcomes (3)

• 6 Minute Walk Test

  The six minute walk test 96 The six minute walking test (6MWT) was developed by the American Thoracic Society and it was officially introduced in 2002, coming along with a comprehensive guideline. The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity. The 6-minute walk test (6MWT) is commonly used to measure the functional exercise capacity in chronic patients with cardiovascular disease.

  8 weeks

• The Beck Depression Inventory Scale

  The Beck Depression Inventory (BDI, BDI-1A, BDI-II), created by Aaron T. Beck, is a 21-question multiple-choice self-report inventory, one of the most widely used psychometric tests for measuring the severity of depression. Its development marked a shift among mental health professionals, who had until then, viewed depression from a psychodynamic perspective, instead of it being rooted in the patient's own thoughts. Each question had a set of at least four possible responses, ranging in intensity. Higher total scores indicate more severe depressive symptom.

  8 weeks

• SF- 36 SF-36

  SF- 36-Item Short Form Survey (SF-36) is an outcome measure instrument that is often used, well-researched, self-reported measure of health. It stems from a study called the Medical Outcomes Study for the objective measure of the quality of life. It comprises 36 questions that cover eight domains of health. The SF-36 is often used as a measure of a person or population's quality of life (QOL).

  8 weeks

Study Arms (3)

aerobic exercises

ACTIVE COMPARATOR

Aerobic exercises i-e treadmill walking, bicycle ergometer, Treadmill

Other: aerobic exercises

resistance training

EXPERIMENTAL

resistance exercise training gluteal bridge, calf raises, squats, seated shoulder press,

Other: resistance training

medication

PLACEBO COMPARATOR

only on drugs no exercise is given

Drug: medication

Interventions

aerobic exercises OTHER

group A will receive aerobic training like walking and cycling for 03 times per week approximately each exercise 5 to 10 minutes for 8 weeks.

aerobic exercises

resistance training OTHER

this group will receive resistance training like gluteal bridge, calf raise, squats, seated shoulder press for 03 times per week approximately each exercise 5 to 10 minutes for 8 weeks.

resistance training

medication DRUG

This group will be just on medication and no exercise will be given to this group

medication

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both males and females Age between 40 to 60 years Diagnosed cases of hypothyroidism Duration: 2 years being diagnosed Patients who easily perform exercises

You may not qualify if:

• Patients with serious comorbidities like cancer Uncontrolled hypertension Vitally unstable patients Red flags for physiotherapy

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Abbottabad medical complex

Abbottābād, Khyber Pakhtunkhwa, 21300, Pakistan

RECRUITING

MeSH Terms

Interventions

Exercise; Resistance Training; Dosage Forms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Pharmaceutical Preparations; Technology, Pharmaceutical; Investigative Techniques

Study Officials

• saira jahan

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Imran Amjad, Phd

CONTACT

03324390125; imran.amjad@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 18, 2024
• First Posted: April 22, 2024
• Study Start: April 1, 2024
• Primary Completion: June 1, 2024
• Study Completion: June 1, 2024
• Last Updated: April 22, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)