Comparative Effects of Resistance Training and Neuromuscular Training in Runners

NCT07329517 | Completed DMC

• 1 other identifier: REC/RCR&AHS/24/0494
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 2

Brief Summary

This randomized controlled trial will include a sample of 38 young runners, calculated using epitool. Participants will be recruited through non-probability convenient sampling and randomly assigned to one of two groups: Group A (runner-specific resistance training) and Group B (neuromuscular training), with 19 participants in each group. The study will be conducted at the University of Lahore.

Conditions

Patellofemoral Pain Syndrome

Keywords

resistance training; neuromuscular training; runners

Outcome Measures

Primary Outcomes (3)

• vertical Jump Test

  The vertical jump test measures explosive leg power by comparing an athlete's standing reach with the height they achieve when jumping. The difference between these two points indicates their vertical jump height, which reflects lower-body strength and is commonly used in sports to assess athletic performance potential.

  6 weeks

• IKDC questionnaire

  The IKDC questionnaire is a patient-reported tool that measures knee symptoms, daily function, and sports activity, producing a score from 0 (severe problems) to 100 (optimal function). It is widely used in orthopedics to track recovery and compare treatment outcomes for various knee conditions.

  6 weeks

• Star excursion balance test (SEBT)

  The Star Excursion Balance Test (SEBT) is a dynamic assessment of balance and lower-limb function. In the test, a person stands on one leg and reaches in multiple directions with the other leg, challenging stability, strength, and flexibility. It is commonly used in sports and rehabilitation to detect injury risks, evaluate postural control, and monitor recovery progress.

  6 weeks

Study Arms (2)

Group A

EXPERIMENTAL

19 participants will be in group 1 and allocated for resistance training group (RT Group)

Other: Resistance training

Group B

ACTIVE COMPARATOR

19 participants will be in group B and allocated for neuromuscular training (NT Group)

Other: Neuromuscular Training

Interventions

Resistance training OTHER

19 participants will be in group A and allocated for resistance training

Group A

Neuromuscular Training OTHER

19 participants will be in group B and allocated for neuromuscular training

Group B

Eligibility Criteria

• Age: 18 Years - 30 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Runners aged 18-30 years
• Runners having at least one year of playing
• Male Runners with Patellofemoral pain syndrome
• Not involved in resistance or neuromuscular training

You may not qualify if:

• Individuals with other acute or chronic knee injuries
• history of knee surgery
• Runners who have not been consistently running for at least 6 months prior to the study

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (2)

The University of Lahore

Lahore, Punjab Province, Pakistan

Location

University of Lahore

Lahore, Punjab Province, Pakistan

Location

Related Publications (8)

• Bolgla LA, Boling MC. An update for the conservative management of patellofemoral pain syndrome: a systematic review of the literature from 2000 to 2010. Int J Sports Phys Ther. 2011 Jun;6(2):112-25.

  PMID: 21713229 BACKGROUND

• Coburn SL, Barton CJ, Filbay SR, Hart HF, Rathleff MS, Crossley KM. Quality of life in individuals with patellofemoral pain: A systematic review including meta-analysis. Phys Ther Sport. 2018 Sep;33:96-108. doi: 10.1016/j.ptsp.2018.06.006. Epub 2018 Jun 28.

  PMID: 30059951 BACKGROUND

• Rabelo ND, Lima B, Reis AC, Bley AS, Yi LC, Fukuda TY, Costa LO, Lucareli PR. Neuromuscular training and muscle strengthening in patients with patellofemoral pain syndrome: a protocol of randomized controlled trial. BMC Musculoskelet Disord. 2014 May 16;15:157. doi: 10.1186/1471-2474-15-157.

  PMID: 24884455 BACKGROUND

• Clijsen R, Fuchs J, Taeymans J. Effectiveness of exercise therapy in treatment of patients with patellofemoral pain syndrome: systematic review and meta-analysis. Phys Ther. 2014 Dec;94(12):1697-708. doi: 10.2522/ptj.20130310. Epub 2014 Jul 31.

  PMID: 25082920 BACKGROUND

• Rixe JA, Glick JE, Brady J, Olympia RP. A review of the management of patellofemoral pain syndrome. Phys Sportsmed. 2013 Sep;41(3):19-28. doi: 10.3810/psm.2013.09.2023.

  PMID: 24113699 BACKGROUND

• Luo Y, Chen X, Shen X, Chen L, Gong H. Effectiveness of Kinesio tape in the treatment of patients with patellofemoral pain syndrome: A systematic review and meta-analysis. Medicine (Baltimore). 2024 Jun 7;103(23):e38438. doi: 10.1097/MD.0000000000038438.

  PMID: 38847704 BACKGROUND

• Masoudi A, Chemane N, Useh U, Bello B, Magida N. Effectiveness of Self-Management Programs Among Athletes With Patellofemoral Pain Syndrome: Protocol for a Systematic Review. JMIR Res Protoc. 2024 Nov 1;13:e58340. doi: 10.2196/58340.

  PMID: 39485375 BACKGROUND

• Nunes GS, de Moraes WSLA, de Souza Sampaio V, Seda NR, Dos Santos Mouta G, Dangui AJM, de Souza Petersen R, Nakagawa TH. Are Changes in Dynamic Knee Movement Control Related to Changes in Pain or Function in People With Knee Disorders? A Systematic Review and Meta-analysis. J Orthop Sports Phys Ther. 2023 Jul;53(7):388-401. doi: 10.2519/jospt.2023.11628.

  PMID: 37068162 BACKGROUND

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Haleema Najeeb, DPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: The Outcome Assessors are blind
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized control design

Study Record Dates

• First Submitted: December 29, 2025
• First Posted: January 9, 2026
• Study Start: November 21, 2024
• Primary Completion: October 5, 2025
• Study Completion: November 5, 2025
• Last Updated: January 9, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

PA (2)