Effects of Specific Thoracic Spine Mobilizations on Muscle Activity in a Healthy Volunteer Population

NCT06374862 | Completed

• 1 other identifier: PI2024_843_0008
• Study Type: interventional
• Target: 156
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, the investigators will examine the effect of manual therapy on the thoracic spine and its impact on the muscular strength gain of the thoracic extensors. Treatment with manual therapy, as described by Maitland, consists of a specific mobilization of the thoracic spine in the postero-anterior direction on the transverse and spiny processes of the thoracic vertebrae. To ensure the relevance of the measures, and to better control the occurrence of biases inherent to the practice of manual therapy, the investigators constituted three distinct groups: an intervention group, a control group and a group without intervention. In short, this methodology will allow us to explore in detail the effects of specific spinal mobilization on motor control, while taking into account placebo response elements and natural variations in the results

Conditions

Musculoskeletal Manipulations; Range of Motion; Muscle Strength; Peripheral Joints in Upper Quarters

Keywords

Musculoskeletal Manipulations; Range of Motion; Muscle Strength; peripheral joints in upper quarters

Outcome Measures

Primary Outcomes (1)

• electrical activity assessment of the spine extensor muscles using EMG

  1 hour

Study Arms (3)

Interventional

EXPERIMENTAL

This study is of an interventional nature, because the investigators want to objectively assess the impact of specific mobilization on neuromuscular functioning, thanks to surface EMG, before and after a specific mobilization of the spine.

Other: mobilization

control

SHAM COMPARATOR

This approach will help to determine whether there is spontaneous modulation of neuromuscular activity in the absence of intervention. Thus, the investigators can distinguish the effects of intervention from natural variations in the healthy subject.

Other: no effect

no interventional

NO INTERVENTION

A control group was also integrated to assess whether a mobilization identified as "no effect" could modulate neuromuscular activity by a placebo effect. This approach will allow to disentangle the real effects of mobilization from those that could result from psychomotor responses

Interventions

mobilization OTHER

specific mobilization on neuromuscular functioning, thanks to surface EMG, before and after a specific mobilization of the spine

Interventional

no effect OTHER

a mobilization identified as "no effect" could modulate neuromuscular activity by a placebo effect.

control

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Ages 18 to 65,
• healthy volunteer,
• membership in a social security scheme

You may not qualify if:

• Severe spinal trauma within the last 6 months
• history of low back pain, back pain, and/or neck pain within the last 6 months,
• history of spinal surgery,
• history of chronic systemic disease (cardiac, respiratory, diabetes, etc.),
• volunteer with Pacemaker, history of rheumatological pathology (rheumatoid arthritis, ankylosing spondylitis, Scheuermann's disease, etc.),
• patient under guardianship,curatorship, safeguard of justice, patient deprived of liberty, pregnant woman and patient without Red Flags Social Security described in literature.

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

Study Sites (1)

CHU Amiens Picardie

Amiens, Picardie, 80054, France

Location

MeSH Terms

Interventions

No-Observed-Adverse-Effect Level

Intervention Hierarchy (Ancestors)

Toxicity Tests; Investigative Techniques; Toxicological Phenomena; Pharmacological and Toxicological Phenomena; Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 16, 2024
• First Posted: April 19, 2024
• Study Start: March 28, 2024
• Primary Completion: October 28, 2025
• Study Completion: February 16, 2026
• Last Updated: March 31, 2026

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)