Τhe Effect of Lumbar Spine Mobilization and Manipulation on Pressure Pain Threshold in Patients with NSLBP

NCT06757400 | Completed

• 1 other identifier: 65273- 07/07/2023
• Study Type: interventional
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

Manual therapy, including mobilizations and manipulations, appears to be as effective as other types of therapy for chronic low back pain. The aim of this cross-sectional study is to compare the effects of lumbar spine mobilization and manipulation on the pressure pain threshold in patients with non-specific chronic low back pain.

Conditions

Low Back Pain; Lumbago

Keywords

non-specific low back pain; manual therapy; hypoalgesia; pressure pain threshold

Outcome Measures

Primary Outcomes (1)

• 1. Pressure pain threshold

  Changes between pre- and post- intervention in Pressure Pain Threshold will be measured using at the L5 spinous process, upper trapezius muscle the tibialis anterior muscle. The COMPACT DIGITAL ALGOMETER CAPACITIES TO: 100 lbf / 50 kgf / 500 N, will be used by an independent assessor. The assessor will be blinded to participants' group.

  Baseline and 15 minutes

Secondary Outcomes (2)

• Range Of Motion (ROM)

  Baseline and 15 minutes

• Pain Intensity

  Baseline and 15 minutes

Study Arms (2)

Mobilization

EXPERIMENTAL

27 patients with chronic low back pain will be assigned to receive one intervention with grade IV posteroanterior (PA) mobilization in the Lumbar spine

Other: Mobilization; Other: manipulation

Manipulation

ACTIVE COMPARATOR

27 patients with chronic low back pain will be assigned to receive one intervention with lumbar manipulation

Other: Mobilization; Other: manipulation

Interventions

Mobilization OTHER

Mobilization will be conducted on an examination table with the subject in prone position. Therapist will place his hypothenar to the most hypomobile lumbar spine segment after assessment.It will be a posteroanterior (PA) direction tecnique, Maitland's GRADE 4, 3 sets of 60 seconds duration for each set.

Manipulation; Mobilization

manipulation OTHER

Manipulation will be conducted on an examination table with the subject in right lateral decubitus. It will be a rotary manipulation to the most hypomobile lumbar spine segment after assessment.

Manipulation; Mobilization

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• to 60 years old
• diagniosed with non specific low back pain
• symptoms lasting for more than 12 weeks

You may not qualify if:

• spinal fractures,
• neurological impairment due to herniated spinal disc,
• spondylolisthesis,
• joint degenerative diseases,
• osteoporosis,
• spinal infections,
• cauda equina syndrome,
• spinal tumors or bone marrow malignancies,
• spinal surgeries
• history of cancer,
• use of steroids

Sponsors & Collaborators

• University of West Attica: lead

Study Sites (1)

Thomas Sampsonis

Peristeri, Αττικης, 12135, Greece

Location

Related Publications (5)

• Dal Farra F, Risio RG, Vismara L, Bergna A. Effectiveness of osteopathic interventions in chronic non-specific low back pain: A systematic review and meta-analysis. Complement Ther Med. 2021 Jan;56:102616. doi: 10.1016/j.ctim.2020.102616. Epub 2020 Nov 13.

  PMID: 33197571 BACKGROUND

• Childs JD, Fritz JM, Flynn TW, Irrgang JJ, Johnson KK, Majkowski GR, Delitto A. A clinical prediction rule to identify patients with low back pain most likely to benefit from spinal manipulation: a validation study. Ann Intern Med. 2004 Dec 21;141(12):920-8. doi: 10.7326/0003-4819-141-12-200412210-00008.

  PMID: 15611489 BACKGROUND

• Rubinstein SM, de Zoete A, van Middelkoop M, Assendelft WJJ, de Boer MR, van Tulder MW. Benefits and harms of spinal manipulative therapy for the treatment of chronic low back pain: systematic review and meta-analysis of randomised controlled trials. BMJ. 2019 Mar 13;364:l689. doi: 10.1136/bmj.l689.

  PMID: 30867144 BACKGROUND

• Arribas-Romano A, Fernandez-Carnero J, Molina-Rueda F, Angulo-Diaz-Parreno S, Navarro-Santana MJ. Efficacy of Physical Therapy on Nociceptive Pain Processing Alterations in Patients with Chronic Musculoskeletal Pain: A Systematic Review and Meta-analysis. Pain Med. 2020 Oct 1;21(10):2502-2517. doi: 10.1093/pm/pnz366.

  PMID: 32100027 BACKGROUND

• Coronado RA, Gay CW, Bialosky JE, Carnaby GD, Bishop MD, George SZ. Changes in pain sensitivity following spinal manipulation: a systematic review and meta-analysis. J Electromyogr Kinesiol. 2012 Oct;22(5):752-67. doi: 10.1016/j.jelekin.2011.12.013. Epub 2012 Jan 30.

  PMID: 22296867 BACKGROUND

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, Physiotherapy Dept, University of West Attica

Study Record Dates

• First Submitted: May 26, 2024
• First Posted: January 3, 2025
• Study Start: November 4, 2023
• Primary Completion: February 28, 2024
• Study Completion: April 23, 2024
• Last Updated: January 6, 2025

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

GR (1)