The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.

NCT06340061 | Active Not Recruiting

• 1 other identifier: Qianyu Wu
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Conditions

Glaucoma

Outcome Measures

Primary Outcomes (6)

• IOP

  Intraocular pressure

  through study completion, an average of 2 years.

• bIOP

  Biomechanical intraocular pressure. Corneal Biomechanics Parameters.

  through study completion, an average of 2 years.

• ACD

  Anterior chamber depth. Anterior Chamber Parameters.

  through study completion, an average of 2 years.

• ACW

  Anterior chamber width. Anterior Chamber Parameters.

  through study completion, an average of 2 years.

• SSI

  Stress-strain index. Corneal Biomechanics Parameters.

  through study completion, an average of 2 years.

• VF

  visual field. The severity of glaucoma is mainly based on the damage of the visual field

  through study completion, an average of 2 years.

Study Arms (2)

Treatment group

Other: Observational study

Control group

Interventions

Observational study OTHER

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Treatment group

Eligibility Criteria

• Age: 22 Years - 79 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Outpatients

You may qualify if:

• Clinical diagnosis of primary glaucoma.
• Must be able to cooperate to complete the inspection.

You may not qualify if:

• Secondary glaucoma.
• Corneal disease (E. g., keratitis, corneal scarring) that the investigator believes may affect the examination.
• trauma
• congenital eye malformations

Sponsors & Collaborators

• Henan Provincial People's Hospital: lead

Study Sites (1)

Henan Provincial People's Hospital

Zhengzhou, Henan, 450003, China

Location

MeSH Terms

Conditions

Glaucoma

Interventions

Observation

Condition Hierarchy (Ancestors)

Ocular Hypertension; Eye Diseases

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Study Officials

• Qian Liu

  Henan Provincial People's Hospital, Henan Eye Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 10, 2024
• First Posted: April 1, 2024
• Study Start: October 20, 2022
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: April 1, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)