NCT06333756

Brief Summary

We will explored the effect of cross education training on different cortex functional connectivity, cortex and muscle functional connectivity, and maximal voluntary contraction. Healthy participants receive cross education training of the elbow flexor (12 rep./set, 3sets, 60%MVC, 180°/s, eccentric).Maximal voluntary contraction, electroencephalogram and electromyogram will record during cross education tasks to determine the effects of cross education training on cortical network and muscle functional connectivity

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2021

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2022

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

March 20, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 27, 2024

Completed
Last Updated

March 27, 2024

Status Verified

December 1, 2022

Enrollment Period

12 months

First QC Date

March 20, 2024

Last Update Submit

March 20, 2024

Conditions

Keywords

cross education, functional connectivity

Outcome Measures

Primary Outcomes (3)

  • Corticocortical coherence

    Level of electroencephalography and electromyography synchronization in frequency domain when participants maintain 20% maximal voluntary contraction

    Measured immediately after cross education training

  • Corticomuscular coherence

    Level of electroencephalography and electromyography synchronization in frequency domain when participants maintain 20% maximal voluntary contraction

    Measured immediately after cross education training

  • Maximal voluntary contraction

    The ability to generate maximal voluntary elbow flexor force

    Measured immediately after cross education training

Study Arms (1)

Cross education training group

EXPERIMENTAL

Cross education on elbow flexor

Other: Cross education

Interventions

Cross education training of the biceps brachii (12 rep./set, 3sets, 60%MVIC,180°/s, eccentric contraction)

Cross education training group

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy adults who are 20-40 years old

You may not qualify if:

  • Upper extremity (UE) pain or discomfort
  • Medical condition that substantially influenced their UE strength
  • Experience of UE surgery
  • Paresthesia in UE
  • Open wound on UE

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Yang-Ming University

Taipei, 112, Taiwan

Location

Study Officials

  • Li-Wei Chou, Ph.D.

    Department of Physical Therapy and Assistive and Technology ,National Yang-Ming University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Model Details: Parallel Assignment
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2024

First Posted

March 27, 2024

Study Start

May 1, 2021

Primary Completion

April 30, 2022

Study Completion

August 1, 2022

Last Updated

March 27, 2024

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share

Locations