Predictors of Acute Kidney Injury in Critically Ill Children Admitted to PICU.

NCT06328478 | Not Yet Recruiting

• 1 other identifier: Predictors of AKI in PICU.
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Predictors of Acute Kidney Injury in critically ill children admitted to PICU during one year.

Conditions

Acute Kidney Injury

Outcome Measures

Primary Outcomes (1)

• Incidence of acute kidney injury and survival to discharge from the PICU.

  One year from April 2024 to May 2025

Interventions

Observational prospective study. DEVICE

Observational prospective study

Eligibility Criteria

• Age: 1 Month - 18 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All cases of acute kidney injury in pediatrics from 1 month to 18 years incritically ill Patient admitted to PICU Assiut University Children Hospital during one year of the study.

You may qualify if:

• children aged from month to 18 years admitted to PICU between April 2024 to May 2025.

You may not qualify if:

• chronic kidney disease.
• renal malformations.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (7)

• Kellum JA, Romagnani P, Ashuntantang G, Ronco C, Zarbock A, Anders HJ. Acute kidney injury. Nat Rev Dis Primers. 2021 Jul 15;7(1):52. doi: 10.1038/s41572-021-00284-z.

  PMID: 34267223 BACKGROUND

• Basu RK, Kaddourah A, Terrell T, Mottes T, Arnold P, Jacobs J, Andringa J, Goldstein SL; Prospective Pediatric AKI Research Group (ppAKI). Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in critically ill children (AWARE): study protocol for a prospective observational study. BMC Nephrol. 2015 Feb 26;16:24. doi: 10.1186/s12882-015-0016-6.

  PMID: 25882434 BACKGROUND

• Ciccia E, Devarajan P. Pediatric acute kidney injury: prevalence, impact and management challenges. Int J Nephrol Renovasc Dis. 2017 Mar 29;10:77-84. doi: 10.2147/IJNRD.S103785. eCollection 2017.

  PMID: 28435306 BACKGROUND

• Naik S, Sharma J, Yengkom R, Kalrao V, Mulay A. Acute kidney injury in critically ill children: Risk factors and outcomes. Indian J Crit Care Med. 2014 Mar;18(3):129-33. doi: 10.4103/0972-5229.128701.

  PMID: 24701061 BACKGROUND

• Duzova A, Bakkaloglu A, Kalyoncu M, Poyrazoglu H, Delibas A, Ozkaya O, Peru H, Alpay H, Soylemezoglu O, Gur-Guven A, Bak M, Bircan Z, Cengiz N, Akil I, Ozcakar B, Uncu N, Karabay-Bayazit A, Sonmez F; Turkish Society for Pediatric Nephrology Acute Kidney Injury Study Group. Etiology and outcome of acute kidney injury in children. Pediatr Nephrol. 2010 Aug;25(8):1453-61. doi: 10.1007/s00467-010-1541-y. Epub 2010 May 30.

  PMID: 20512652 BACKGROUND

• Cleto-Yamane TL, Gomes CLR, Suassuna JHR, Nogueira PK. Acute Kidney Injury Epidemiology in pediatrics. J Bras Nefrol. 2019 Apr-Jun;41(2):275-283. doi: 10.1590/2175-8239-JBN-2018-0127. Epub 2018 Nov 14.

  PMID: 30465591 BACKGROUND

• Uber AM, Sutherland SM. Acute kidney injury in hospitalized children: consequences and outcomes. Pediatr Nephrol. 2020 Feb;35(2):213-220. doi: 10.1007/s00467-018-4128-7. Epub 2018 Nov 1.

  PMID: 30386936 BACKGROUND

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Central Study Contacts

Martina Adel Labib

CONTACT

01283047091; martina.adel265@gmail.com

Ismail Lotfy Mohamad

CONTACT

01063398967; ismail231@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident physician

Study Record Dates

• First Submitted: March 18, 2024
• First Posted: March 25, 2024
• Study Start: May 1, 2024
• Primary Completion: April 1, 2025
• Study Completion: May 1, 2025
• Last Updated: April 16, 2024

Record last verified: 2024-04