NCT05548725

Brief Summary

Relation between acute kidney injury and mineral bone disease

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2022

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 11, 2022

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 21, 2022

Completed
4 days until next milestone

Study Start

First participant enrolled

September 25, 2022

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 25, 2023

Completed
6 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2023

Completed
Last Updated

September 21, 2022

Status Verified

September 1, 2022

Enrollment Period

1 year

First QC Date

September 11, 2022

Last Update Submit

September 19, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Relation between AKI and mineral bone disease

    Relationship between acute kidney injury and mineral bone disease

    Baseline

Interventions

Investigations to know relationship between acute kidney injury and mineral bone disease

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

c. Sample Size Calculation: 200 cases , 200 controls from December 2021to December 2023 2.4.4 -Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, …): Study techniques: a) Full (thorough) history \& clinical examination. b) Laboratory investigations: * Blood Urea, Serum creatinine * Pth * Ph * Ca * Na * k * Mg * Vit d * Other routine investigations c) Imaging: * Abdominal U/S d) ECG 2.4.5 -Research outcome measures: a. Primary (main): * Identify the association between Acut

You may qualify if:

  • patients with acute kidney injury and their relationship to mineral bone disease.

You may not qualify if:

  • Non hypertensive
  • Non cardiac
  • Active malignancy
  • Acute or chronic liver disease
  • Acute poisoning
  • Covid

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • Agar A, Gulabi D, Sahin A, Gunes O, Hancerli CO, Kilic B, Erturk C. Acute kidney injury after hip fracture surgery in patients over 80 years of age. Arch Orthop Trauma Surg. 2022 Sep;142(9):2245-2252. doi: 10.1007/s00402-021-03969-y. Epub 2021 May 31.

    PMID: 34056678BACKGROUND
  • Koizumi M, Komaba H, Fukagawa M. Parathyroid function in chronic kidney disease: role of FGF23-Klotho axis. Contrib Nephrol. 2013;180:110-23. doi: 10.1159/000346791. Epub 2013 May 3.

    PMID: 23652554BACKGROUND
  • Wesseling-Perry K, Salusky IB. Phosphate binders, vitamin D and calcimimetics in the management of chronic kidney disease-mineral bone disorders (CKD-MBD) in children. Pediatr Nephrol. 2013 Apr;28(4):617-25. doi: 10.1007/s00467-012-2381-8. Epub 2013 Feb 5.

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Central Study Contacts

Asmaa Mohmed, طبيب مقيم

CONTACT

Dr Esam abd elaziz Abdel aziz

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

September 11, 2022

First Posted

September 21, 2022

Study Start

September 25, 2022

Primary Completion

September 25, 2023

Study Completion

October 1, 2023

Last Updated

September 21, 2022

Record last verified: 2022-09