Effect of Cryolipolysis on Insulin Resistance

NCT06223490 | Unknown DMC

• 1 other identifier: Noura Fahmy
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Diabetes mellitus (DM) is a complex chronic illness associated with a state of high blood glucose level, or hyperglycemia, occurring from deficiencies in insulin secretion, action, or both. Diabetes mellitus is the name given to a wide spectrum group of disorders characterized by raised plasma glucose.Type 1 diabetes is characterized by an absolute insulin deficiency due to autoimmune destruction of insulin producing beta cells in the pancreas. most adults with diabetes have type 2, characterized by a relative insulin secretory defect, and target tissue resistance to the effects of insulin.

Conditions

Type 2 Diabetes Mellitus in Obese; Cryotherapy Effect

Keywords

TII DM; Obese Females; Cryolipolysis

Outcome Measures

Primary Outcomes (1)

• Skin fold thickness and estimation of total body fat

  Estimation of body fat for all cases and is done by measuring these parameters : weight in kilograms, height in meters as weight and height will be combined to report BMI in kg/m\^2.

  3 months

Study Arms (2)

Cryolipolysis Group

ACTIVE COMPARATOR

About 30 obese females with type 2 diabetes and will face cryolypolysis in addition to exercise therapy treatment

Procedure: Cryolipolysis

Group of Exercise

ACTIVE COMPARATOR

About 30 obese females with type 2 diabetes and will face exercise therapy treatment only.

Procedure: Cryolipolysis

Interventions

Cryolipolysis PROCEDURE

To investigate the Effect of Cryolipolysis On insulin resistance and In adult type 2 female patients.

Also known as: Exercise therapy

Cryolipolysis Group; Group of Exercise

Eligibility Criteria

• Age: 35 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with incidence of diabetes 5 years ago.
• Patient fasting glucose level is more than 140 mg/dL.
• Age will be ranged from 35 to 45 years
• Body mass index between 25 and 30.
• All patients are medically controlled
• All patients have the same medical care.
• All patients will receive a good explanation of treatment procedures.

You may not qualify if:

• Patients dependent on insulin.
• Renal failure.
• Myocardial infractions.
• Cardiovascular problems.
• Neurological disorders.
• Patients with orthopedic problems (e.g mal or incomplete union of fracture, ankle sprains.
• Abdominal hernia
• Skin disease
• Unstable cases

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Cairo, Egypt

RECRUITING

MeSH Terms

Interventions

Exercise Therapy

Intervention Hierarchy (Ancestors)

Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities

Study Officials

• Akram Abd El Aziz, Assist.Prof

  Cairo University

  STUDY CHAIR

Central Study Contacts

NOURA RAMADAN, MSC

CONTACT

+201158577826; drnourramadaan@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of Physical therapy

Study Record Dates

• First Submitted: January 6, 2024
• First Posted: January 25, 2024
• Study Start: November 1, 2023
• Primary Completion: January 20, 2024
• Study Completion: January 30, 2024
• Last Updated: January 25, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)