The Effect of Brief Skin Cooling on Isometric Muscle Strength

NCT06079437 | Completed

• 1 other identifier: CISVWSA
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

There is sympathetic innervation of the muscular spindle. The application of cold to the skin provides an increase in sympathetic activity. In rehabilitation practice, short-term local cold is applied to the skin to provide motor facilitation. The aim of this study was to examine whether short-term local cold application provides an increase in isometric contractile strength and, if so, whether this effect is related to muscle spindle activity.

Conditions

Cryotherapy Effect

Keywords

soleus v-wave; sympathetic outflow; muscle spindle; cold stress test; sympathetic system; contractile force; motor facilitation

Outcome Measures

Primary Outcomes (4)

• Heart rate

  Heart rate was monitored with DII derivation electrocardiographic recording. Heart rate was reported as beats per minute.

  during procedure

• Soleus H-reflex amplitude

  By stimulating the tibial nerve with an electrical current, the Soleus H-reflex was obtained. Its peak to peak amplitude will be measured in microvolts.

  during procedure

• Soleus V-wave amplitude

  Soleus V-wave was obtained by applying an electrical current to the tibial nerve during maximum voluntary contraction (MCV). Peak-to-peak amplitude was measured in microvolts.

  during procedure

• Maximum isometric muscle strength

  Maximum isometric muscle strength of ankle plantar flexors was measured using a force sensor

  during procedure

Secondary Outcomes (1)

• Skin temperature

  during procedure

Study Arms (1)

experimental group

EXPERIMENTAL

Heart rate, maximum isometric muscle strength, Soleus H-reflex, M-wave, and V-wave measurements were taken in three consecutive periods. First-period maximal isometric contraction; second-period maximal isometric contraction + cold pressure test; third-period maximal isometric contraction + Cheering

Procedure: Cheer; Procedure: The cold pressure test

Interventions

Cheer PROCEDURE

Maximum isometric contraction was performed with cheering.

experimental group

The cold pressure test PROCEDURE

Maximum isometric contraction was performed with the cold pressure test.

experimental group

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Being healthy
• Being a young adult (20-45 years old)
• Volunteer

You may not qualify if:

• Scar, dermatitis, etc. in the skin tissue where the surface electromyography electrode will be placed
• Upper extremity bone and joint disease, history of neuromuscular disease
• Heart disease, Hypertension
• Cold intolerance

Sponsors & Collaborators

• Istanbul Physical Medicine Rehabilitation Training and Research Hospital: lead

Study Sites (1)

Istanbul Physical Medicine Rehabilitation Training & Research Hospital

Istanbul, 34173, Turkey (Türkiye)

Location

Study Officials

• Mert Cetin, MD

  İstanbul Physical Therapy Rehabilitation Training & Research Hosptial

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 29, 2023
• First Posted: October 12, 2023
• Study Start: April 10, 2023
• Primary Completion: April 20, 2023
• Study Completion: April 22, 2023
• Last Updated: October 12, 2023

Record last verified: 2023-10

Locations

TU (1)