Efficacy of Virtual Reality Exercises on Sarcopenia in Patients With Liver Transplantation

NCT06209073 | Unknown

• 1 other identifier: P.T.REC/012/003915
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study will be conducted to investigate the effect of virtual reality exercises on hand grip strength, pinch strength, quadriceps muscle strength, exercise capacity, fatigue, and quality of life in patients with liver transplantation.

Conditions

Sarcopenia

Keywords

liver transplantation; virtual reality; quality of life

Outcome Measures

Primary Outcomes (1)

• Hand grip strength

  JAMAR hand grip dynamometer will be used to measure hand grip strength

  up to six weeks

Secondary Outcomes (6)

• Pinch strength

  up to six weeks

• Respiratory function

  up to six weeks

• Fatigue

  up to six weeks

• life disability

  up to six weeks

• exercise capacity

  up to six weeks

Study Arms (2)

virtual reality exercise

EXPERIMENTAL

the patients will receive virtual reality and conventional therapy three times a week for six weeks

Other: Virtual Reality exercise; Other: conventional treatment

conventional treatment

EXPERIMENTAL

the patients will receive conventional treatment three times a week for six weeks

Other: conventional treatment

Interventions

Virtual Reality exercise OTHER

after explaining the treatment method for patients, the patients will perform full body aerobic exercise by applying kick boxing to destroy walls of rock; the patient moves most of body muscles in this game. He or she flex and extend the shoulder and the elbow with flexion and extension in the knee. squatting exercise, endurance exercise, coordination for arm and shoulder exercise will also performed in virtual reality

virtual reality exercise

conventional treatment OTHER

the patients will receive conventional treatment in the form of aerobic exercise, resistance exercise and endurance exercise.

conventional treatment; virtual reality exercise

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Sixty patients suffer from sarcopenia with liver transplantation. The age of patients ranges from (18:65) years. All patients must be conscious. Patients suffer from muscle weakness Patients suffer from fatigue Patients with low muscle endurance Patients' cases must be stable to deal with them

You may not qualify if:

• Patients will be excluded if they have any of the following:
• Any sign of acute rejection of the transplanted organ Acute hemorrhage Electrolyte imbalance Physiological instability Sever neurologic complication Sever cardiovascular co-morbidities

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy

Cairo, Egypt

Location

MeSH Terms

Conditions

Sarcopenia

Interventions

Exergaming

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Sara A Elshrief, Bsc

  Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sata A Elshrief, Bsc

CONTACT

01065095990; ssyara14@yahoo.com

Nabil M Ismail, Assist. Prof

CONTACT

0120133613; nabil.mahmoud@cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: opaque sealed envelop
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator: nabil mahmoud ismail abdel-Aal

Model Details: virtual reality and conventional treatment

Study Record Dates

• First Submitted: December 28, 2023
• First Posted: January 17, 2024
• Study Start: January 25, 2024
• Primary Completion: June 20, 2024
• Study Completion: June 20, 2024
• Last Updated: January 17, 2024

Record last verified: 2023-01

Locations

EG (1)