NCT05767541

Brief Summary

The goal of this clinical trial is to compare the effectiveness of two exercises to improve physical functioning of older adults with sarcopenia. the primary aim of this RCT is: To measure the influence of pilates exercises versus resistance training in elderly with sarcopenia. To introduce an affordable, effective and safe exercise care program, which prioritizes to make geriatric population independent. Participants will be assessed for all outcome measures change at baseline and after 3 weeks following an exercise intervention. Participants enrolled in pilates exercise group will receive total of 9 exercises and participants enrolled in resistance exercise group will receive total of 8 exercises.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2022

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2022

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

December 24, 2022

Completed
3 months until next milestone

First Posted

Study publicly available on registry

March 14, 2023

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 2, 2024

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2024

Completed
Last Updated

February 6, 2025

Status Verified

February 1, 2025

Enrollment Period

1.3 years

First QC Date

December 24, 2022

Last Update Submit

February 4, 2025

Conditions

Keywords

SarcopeniaResistance trainingExercise Movement Techniques

Outcome Measures

Primary Outcomes (1)

  • Short physical performance battery assessment tool.

    The SPPB assesses physical performance through balance, strength, and gait. .Each test is scored from 0 (inability to perform the task) to 4 points (best test performance).The SPPB total score ranges from 0 (worst performance) to 12 points (best performance) and categorically evaluates performance in the tests using three classes of scores: three classes: 0-6 points (poor performance), 7-9 points (moderate performance), and 10-12 points (good performance).

    3 weeks, change from baseline

Secondary Outcomes (3)

  • Time up and go test

    3 weeks, change from baseline

  • sit and reach test

    3 weeks, change from baseline

  • 2-minute step test

    3 weeks, change from baseline

Study Arms (2)

Pilates group

EXPERIMENTAL

The Pilates technique consists of a series of low-impact exercises that build strength and flexibility throughout the body. All exercises performed 3 days in a week, 3 visits per week total of 9 sessions. In first week participants will perform 1 set of each exercise with 10 repetitions. In second week 2 sets of each exercise with 12 repetitions and in the third week both groups will perform 3 sets of each exercise with 15 repetitions with a rest interval of 2-3 minutes between sets.

Other: Pilates exercises

Resistance group

ACTIVE COMPARATOR

Resistance exercises are anaerobic physical exercises, uses low number of repetitions with adjustable intensity contribute to hypertrophy of the muscle fibers and increase in muscle strength. All exercises performed 3 days in a week, 3 visits per week total of 9 sessions. In first week participants will perform 1 set of each exercise with 10 repetitions. In second week 2 sets of each exercise with 12 repetitions and in the third week both groups will perform 3 sets of each exercise with 15 repetitions with a rest interval of 2-3 minutes between sets.

Other: Resistance exercises

Interventions

The Pilates technique consist of hundred, swimming, prone leg lift, single leg stretch, spine stretch forward, arm circles, imprint and release, one leg circles and mini squat.

Pilates group

Resistance training include leg press, shoulder press, bench press, back arm press, seated row, knee extension, leg curl and seated calf raise

Resistance group

Eligibility Criteria

Age60 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Referred and screened patients with sarcopenia from medicine, family medicine and neurology OPD at Dow University Hospital Ojha Campus, Karachi.
  • Patients from 60 to 70 years of age
  • Both male and female.
  • Patients who consent to participate

You may not qualify if:

  • Being bedridden
  • Implanted pacemaker
  • Recent history of any fracture
  • Patients with cognitive \& neurological impairment
  • Already enrolled in any exercise intervention program
  • Known case of patients with malignancy
  • Patients on steroids

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Dow University of Health and Sciences

Karachi, Sindh, 74200, Pakistan

Location

Dow University of Health and Sciences

Karachi, Pakistan

Location

Related Publications (1)

  • Mueller D, Redkva PE, Fernando de Borba E, Barbosa SC, Krause MP, Gregorio da Silva S. Effect of mat vs. apparatus pilates training on the functional capacity of elderly women. J Bodyw Mov Ther. 2021 Jan;25:80-86. doi: 10.1016/j.jbmt.2020.11.012. Epub 2020 Nov 16.

Related Links

MeSH Terms

Conditions

Sarcopenia

Interventions

Exercise Movement Techniques

Condition Hierarchy (Ancestors)

Muscular AtrophyNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesAtrophyPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsSigns and Symptoms

Intervention Hierarchy (Ancestors)

Physical Therapy ModalitiesTherapeutics

Study Officials

  • Syeda Ariba Shoaib

    Dow University of Heath Sciences

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 24, 2022

First Posted

March 14, 2023

Study Start

October 1, 2022

Primary Completion

January 2, 2024

Study Completion

January 31, 2024

Last Updated

February 6, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations