Effects of Fascial Plan Blocks on Pulmonary Functions

NCT06144307 | Completed

• 1 other identifier: 2023/04-3
• Study Type: observational
• Target: 1
• Locations: 1 country
• Sites: 1

Brief Summary

In addition to the traumatic effect of the operation, the effort to immobilize the auxiliary respiratory muscles due to pain causes a decrease in postoperative respiratory function (especially in thoracic and upper abdominal surgeries). In addition, superficial and tachypneic breathing caused by the inability of the patient to take deep breaths with pain leads to closure of small airways and increase in intrapulmonary shunts, resulting in hypoxia. Postoperative pain management is important not only to prevent pain but also to reduce pulmonary complications that may occur due to changes in lung function and to reduce mortality and morbidity by controlling the stress response. Pain after nausea and vomiting is the most common reason for hospitalization after laparoscopic surgery. Although pain in laparoscopic cholecystectomy (LC) has many components including incisional, visceral and reflected, the primary source of pain is incisional pain. A multimodal analgesic approach (NSAII, paracetamol, opioids, local infiltration, facial plane blocks and paravertebral and periparavertebral blocks) is recommended. Regional anesthesia combined with general anesthesia reduces the stress response associated with surgery and reduces the need for opioid use. Subcostal TAP Block; injection of local anesthetic between the internal oblique and transversus abdominis muscles in the upper quadrant of the anterior abdominal wall blocks the anterior cutaneous branches of the thoracoabdominal nerves. External Oblique Fascial Plane Block (EOIB); blocks both the anterior and lateral cutaneous branches of the thoracoabdominal nerves. It is performed between the 6th-7th costae. There is a cutaneous sensory block between T6-T9 in the midabdomen and T6-T10 in the anterior axillary line. The conventional method is the administration of intravenous opioids as a method of postoperative analgesia when the routine block cannot be performed due to a contraindication.

Conditions

Pain, Postoperative; Respiratory Function Loss

Keywords

postoperative pain; plane block; pulmonary function

Outcome Measures

Primary Outcomes (1)

• the effect of plane blocks on postoperative pulmonary function

  The effect of pain relief after plane blocks on postoperative pulmonary function

  during the postoperative 24 hours

Secondary Outcomes (3)

• opioid consumption

  during the postoperative 24 hours

• Incidence of nausea and vomiting

  during the postoperative 24 hours

• quality of recovery-15

  during the postoperative 24 hours

Study Arms (3)

External Oblique Fascial Plan Block

Procedure: plane block

Subcostal Transversus Abdominis Plan Block

Procedure: plane block

Control

Interventions

plane block PROCEDURE

injection of local anesthetic to the myofascial plane

External Oblique Fascial Plan Block; Subcostal Transversus Abdominis Plan Block

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who will undergo cholecystectomy between the ages of 18-65

You may qualify if:

• years old
• ASA I-II-III risk group
• Patients whose consent was obtained with an informed consent form
• She will undergo a cholecystectomy operation
• Patients to be cooperative for SFT test

You may not qualify if:

• \<18 years and \>65 years
• ASA ≥ IV
• Pulmonary function test below 50% of the expected value
• Known diaphragm paralysis
• Body mass index \>30
• Myocardial infarction within 1 month
• Dementia or confusion
• Lack of cooperation
• People with respiratory diseases
• Congestive heart failure
• Unstable hypertension
• Thoracoabdominal surgery

Sponsors & Collaborators

• Zonguldak Bulent Ecevit University: lead

Study Sites (1)

Zonguldak Bülent Ecevit University Faculty of Medicine

Kozlu, Zonguldak Province, 67600, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 16, 2023
• First Posted: November 22, 2023
• Study Start: December 1, 2023
• Primary Completion: October 30, 2024
• Study Completion: December 31, 2024
• Last Updated: May 28, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)