Prediction of the Risks of Cardiovascular Mortality

NCT06103448 | Unknown

• 1 other identifier: IGA-FZS-2023-6
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Monitoring risks of cardiovascular diseases in working population (18 - 65 years old) by monitoring their BMI, ankle-brachial index with pulse wave velocity, cholesterol and glycemia.

Conditions

Cardiovascular Diseases; Cardiovascular Morbidity; Stroke; Embolism; Cardiac Arrest

Keywords

ankle-brachial index; cardiovascular mortality; prevention

Outcome Measures

Primary Outcomes (6)

• Detection of glycemia, HDL, LDL and triacylglyceride levels

  Glycemia, HDL, LDL and triacylglyceride levels (mmol/l) will be measured from drops of blood by point-of-care analysers

  5 minutes

• Body composition

  Using body composition scale the following markers will be counted: bone mass, body fat, muscle mass, water levels. All results will be in %

  3 minutes

• Ankle-brachial index

  Ankle-brachial index (no unit) using ABI-system-100 will be counted from blood pressure measured in all four limbs (mmHg)

  2 minutes

• Ankle brachial pulse wave velocity (baPWV) and carotid femoral pulse wave velocity (cfPWV)

  baPWV and cfPWV will be measure by ABI-system-100 (m/s)

  2 minutes

• Weight

  measured by body composition scale (kg)

  1 minute

• Height

  measured by tailor tape measure (m)

  1 minute

Secondary Outcomes (1)

• BMI

  2 minutes

Interventions

Ankle-brachial index - system 100 DEVICE

Measurement of ankle brachial index on all four limbs, drawing three blood drops for point of care (POC) cholesterol meter and one drop of blood for POC glucometer

Also known as: Point of care cholesterol meter by Lux and point of care Glucometers

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Working individuals with employment contract in Ustecky Region, that are able to consent to assessment, are adults and understand written and spoken Czech language. Random companies from Ustecky region will be approached with the opportunity to participate.

You may qualify if:

• employed in Ustecky Region Czech Republic
• adult
• understands spoken and written Czech
• consents with assessment
• works in a company that consents to assessments of their employees

You may not qualify if:

• deep vein thrombosis
• not currently employed
• on sick leave
• bleeding disorder

Sponsors & Collaborators

• Jan Evangelista Purkyne University: lead

Study Sites (1)

University of Jan Evangelista Purkyně

Ústí nad Labem, 40011, Czechia

Location

MeSH Terms

Conditions

Cardiovascular Diseases; Stroke; Embolism; Heart Arrest

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Embolism and Thrombosis; Heart Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Instructor

Study Record Dates

• First Submitted: October 11, 2023
• First Posted: October 26, 2023
• Study Start: January 1, 2024
• Primary Completion: September 1, 2024
• Study Completion: December 1, 2024
• Last Updated: October 26, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

CZ (1)