NCT06102642

Brief Summary

In patients with high frenal attachment will placement of free gingival graft combined with frenotomy result in gain of width of keratinized gingiva, decrease relapse, improve mucosal healing and have acceptable postoperative pain?

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
12

participants targeted

Target at below P25 for phase_4

Timeline
Completed

Started Oct 2023

Shorter than P25 for phase_4

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2023

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

October 21, 2023

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 26, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2024

Completed
Last Updated

October 26, 2023

Status Verified

October 1, 2023

Enrollment Period

5 months

First QC Date

October 21, 2023

Last Update Submit

October 21, 2023

Conditions

Keywords

FrenotomyFree gingival graftHigh frenum attachmentFrenal relocation

Outcome Measures

Primary Outcomes (1)

  • Width of keratinized tissue

    It will be measured using periodontal probe at T1, T2, T3 and T4

    T1: 5days post-surgery, T2:14 days post-surgery, T3: 2months post-surgery & T4: 3months post-surgery.

Secondary Outcomes (3)

  • Mucosal healing

    T1: 5days post-surgery, T2:14 days post-surgery, T3: 2months post-surgery

  • Post-operative pain

    T2:14 days post-surgery.

  • Relapse

    T4: 3months post-surgery.

Study Arms (1)

Combining Free Gingival Graft with frenotomy procedure

EXPERIMENTAL

evaluate the usage of free gingival graft combined with frenotomy in order to measure the gain in the width of keratinized gingiva, relapse, mucosal healing and postoperative pain.

Biological: Combining free gingival graft with frenotomy procedure

Interventions

The aim of the study is to evaluate the usage of free gingival graft combined with frenotomy in order to measure the gain in the width of keratinized gingiva, relapse, mucosal healing and postoperative pain.

Combining Free Gingival Graft with frenotomy procedure

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Ages 18-40 years old
  • Systemically healthy
  • Gingival and plaque index \<10
  • Good oral hygiene
  • Highly attached mandibular labial frenum.
  • Narrow sulcus depth
  • Thin gingival phenotype

You may not qualify if:

  • Smokers
  • Poor oral hygiene
  • Patient with a physical disability that hinders the upkeep of good oral hygiene measures.
  • Taking any medications that could affect healing
  • Any systemic diseases that delay wound healing.
  • Deep sulcus
  • Thick gingival phenotype
  • Pervious frenal procedures
  • Pregnant or lactating females
  • Pervious periodontal surgery within the last 6 months before the start of the trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Manal Hosny, Professor

    Cairo University

    STUDY DIRECTOR
  • Nada Zazou, Ass Lecturer

    MSA University

    STUDY CHAIR

Central Study Contacts

Mohammed S. Saleh, Bachelor

CONTACT

Manal Hosny, Professor

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Case Series
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master degree student, periodontology department, faculty of dentistry, Cairo University.

Study Record Dates

First Submitted

October 21, 2023

First Posted

October 26, 2023

Study Start

October 1, 2023

Primary Completion

March 1, 2024

Study Completion

August 1, 2024

Last Updated

October 26, 2023

Record last verified: 2023-10