NCT05779800

Brief Summary

After harvesting free gingival graft from the hard palate, Postoperative pain as well as bleeding are the most common complications.Different agents were used to protect the denuded areas on the palate as gelatin sponge, Hyaluronic acid gel and platelet rich fibrin (PRF) but still no gold standard material is present. PICO format: P: patients with mucogingival problems in need for free gingival graft or de-epithelialized connective tissue graft.I: Flowable resin composite stent. C: Periodontal pack. O: Post-operative pain T: day 3, 7, 14, 21 and 42 postoperative. Aim of the study: To compare the effect of flowable composite stent versus periodontal pack applied to palatal donor site after free gingival graft harvesting in terms of post-operative pain reduction.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 15, 2023

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

February 25, 2023

Completed
25 days until next milestone

First Posted

Study publicly available on registry

March 22, 2023

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 8, 2023

Completed
27 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 5, 2023

Completed
Last Updated

March 22, 2023

Status Verified

March 1, 2023

Enrollment Period

9 months

First QC Date

February 25, 2023

Last Update Submit

March 9, 2023

Conditions

Keywords

palatal donor siteGingival RecessionPeriodontal DiseasesProtective Agentsflowable composite

Outcome Measures

Primary Outcomes (1)

  • Post operative pain

    Pain score reported by the patient directly through Visual Analogue Scale score (between 0 and 100. 0: no pain, 10: minimal pain, 50:moderate pain, 100: severe pain)

    on day 7

Secondary Outcomes (2)

  • Color match

    On day 42

  • wound size

    at day 21

Study Arms (2)

Flowable resin composite stent group

EXPERIMENTAL

Flowable resin composite is a bio compatible material used in dental field many years ago.

Device: Flowble resin composite stent

Periodontal pack group

ACTIVE COMPARATOR

Non eugenol containing periodontal pack used in periodontal surgeries to protect the wound. Other name :COE\_PAK

Device: periodontal pack

Interventions

Flowble resin composite is a filling material used in operative dentistry and characterized by being flow and easily adapting the surfaces.

Also known as: NEXOCOMP FLOW
Flowable resin composite stent group

Non eugenol containing dressing supplied in two tubes

Also known as: COE-PAK
Periodontal pack group

Eligibility Criteria

Age21 Years - 62 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with mucogingival defects scheduled for free gingival graft or de-epithelialized connective tissue graft.
  • Systemically healthy

You may not qualify if:

  • Smokers
  • Occlusal trauma at site of graft
  • Pregnancy and lactation
  • Patients allergic to the used agents
  • Severe gagging reflex

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of dentistry, Cairo univesity

Cairo, Manial, 11, Egypt

RECRUITING

MeSH Terms

Conditions

Gingival RecessionPeriodontal Diseases

Condition Hierarchy (Ancestors)

Gingival DiseasesMouth DiseasesStomatognathic DiseasesPeriodontal Atrophy

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
demonstrator

Study Record Dates

First Submitted

February 25, 2023

First Posted

March 22, 2023

Study Start

February 15, 2023

Primary Completion

November 8, 2023

Study Completion

December 5, 2023

Last Updated

March 22, 2023

Record last verified: 2023-03

Locations