Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.

NCT06086691 | Completed DMC

• 1 other identifier: REC/01241 Mian Waleed Ahmed
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars. Many of these products contain numerous ingredients in varied combinations and amounts. Among the more common ingredients are amino acids, protein, creatine, and caffeine

Conditions

Muscle Damage

Keywords

Caffeine; Creatine Kinase; Endurance Training; Fitness Centers; Skeletal Muscle; Strength Training

Outcome Measures

Primary Outcomes (3)

• Serum CK Levels

  Serum CK level is the amount of an enzyme called creatine kinase (CK) in the blood. CK is a type of protein present in the muscle cells in human body need which is essential for proper functioning. Levels of CK can rise after a heart attack, skeletal muscle injury, or strenuous exercise

  Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

• Serum LDH levels

  Lactate Dehydrogenase (LDH) is enzyme found in almost every cell of the human body, including your blood, muscles, brain, kidneys, and pancreas.

  Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

• Serum AST levels

  Aspartate aminotransferase (AST) are enzymes found mainly in the liver, but also found in red blood cells, heart cells, muscle tissue and other organs, such as the pancreas and kidneys.

  Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

Secondary Outcomes (1)

• Rating of fatigue scale/Numeric Rating Scale-Fatigue

  Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

Study Arms (2)

Strength Training

EXPERIMENTAL

Strength training exercises along with caffeine supplementation

Other: Strength Training with Caffeine

Endurance Training

ACTIVE COMPARATOR

Endurance training exercises along with caffeine supplementation

Other: Endurance Training with Caffeine

Interventions

Strength Training with Caffeine OTHER

The intervention protocol consists of 5 types of strength training exercises. The following exercises will be performed for the strength training group: 1. bench press (3 sets of 10 reps) 2. biceps curl (3 sets of 10 reps) 3. triceps pushdown (3 sets of 10 reps) 4. leg press (3 sets of 10 reps) 5. leg extension (3 sets of 10 reps) Strength training would be performed in 3 sets of 10 repetitions with 2 minutes of rest between each exercise. This protocol will be performed in a 30-40-minute session. 10-15 minutes of light warm-up activities will be performed before the start of each exercise session. The intervention sessions would be carried out with a 3-5-day gap between the two intervention sessions.

Strength Training

Endurance Training with Caffeine OTHER

The intervention protocol consists of 3 types of endurance training exercises. The following exercises will be performed by this group: 1. Cycling (15 min) 2. Running (20 min) 3. Rowing (10 min) The intervention sessions would be carried out with a 3-5-day gap between the two intervention sessions.

Endurance Training

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male gym athletes
• Age: 18-40 years
• Athletes with at least three days training session per week

You may not qualify if:

• Athletes already on caffeine supplementation
• Athletes with above normal serum enzyme levels

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Riphah International University (RIU)

Islamabad, Islamabad, 44000, Pakistan

Location

MeSH Terms

Interventions

Resistance Training; Caffeine; Endurance Training

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring

Study Officials

• Noman Sadiq, MS-SPT

  Riphah International University, Islamabad.

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized Crossover Trial

Study Record Dates

• First Submitted: October 11, 2023
• First Posted: October 17, 2023
• Study Start: January 12, 2022
• Primary Completion: November 30, 2022
• Study Completion: January 31, 2023
• Last Updated: November 13, 2023

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)