NCT06900569

Brief Summary

Ashwagandha is an herbal supplement that has a wide range of benefits related to exercise when supplemented for about 8-12 weeks. This study aims to investigate whether short-term Ashwagandha supplementation can enhance muscle recovery following exercise by measuring muscle strength recovery, swelling, and soreness in the biceps.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
19

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 15, 2025

Completed
7 days until next milestone

Study Start

First participant enrolled

March 22, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 28, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2025

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 15, 2025

Completed
Last Updated

February 23, 2026

Status Verified

February 1, 2026

Enrollment Period

1 month

First QC Date

March 15, 2025

Last Update Submit

February 19, 2026

Conditions

Muscle Damage

Outcome Measures

Primary Outcomes (1)

  • Change in isometric biceps strength measured with a dynamometer (Nm)

    72 hours

Secondary Outcomes (3)

  • Change in muscle thickness measured with ultrasound (cm)

    72 hours

  • Change in muscle soreness measured with a visual analog scale with scores ranging from 0 (no soreness) to 10 (maximal soreness)

    72 hours

  • Change in sleep quality with the Pittsburgh Sleep Quality Index with scores ranging from 0 (no sleep problems) to 3 (lowest sleep quality)

    10 days

Study Arms (2)

Placebo

PLACEBO COMPARATOR

600 mg/d placebo for 10 days

Dietary Supplement: Placebo

Ashwagandha

EXPERIMENTAL

600 mg/d Ashwagandha

Dietary Supplement: Ashwagandha

Interventions

AshwagandhaDIETARY_SUPPLEMENT

600 mg/d Ashwagandha

Ashwagandha
PlaceboDIETARY_SUPPLEMENT

600 mg/d placebo

Placebo

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may not qualify if:

  • Conditions that may be affected by exercise (determined by "yes" answers to the "Get Active Questionnaire") Pregnant Breastfeeding
  • Allergies to:
  • Dicalcium Phosphate
  • Cellulose
  • Vegetable magnesium stearate
  • Silica

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Saskatchewan

Saskatoon, Saskatchewan, S7K 2X2, Canada

Location

MeSH Terms

Interventions

Ashwagandha

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 15, 2025

First Posted

March 28, 2025

Study Start

March 22, 2025

Primary Completion

April 30, 2025

Study Completion

May 15, 2025

Last Updated

February 23, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations

CA(1)