Dynamic Respiratory Muscle Strength and Endurance in Childhood Asthma

NCT06053905 | Completed

• 1 other identifier: GO23/241
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Peak inspiratory flow (PIF) may be due to respiratory muscle strength, especially in those with severe airflow obstruction. PIF appears to be lower in children and adolescents with asthma than in non-asthmatics and correlates positively with age, height, weight, and respiratory muscle strength. Although physical activity and fitness are also believed to be important in lung health, the relationship between lung function and physical fitness is unclear. It measures dynamic lung volumes, s-index and PIF and provides information on dynamic lung function in children and adolescents. In this study, the dynamic components of the lung will be compared between asthmatic and healthy children, and the relationship between respiratory parameters and physical assessment, such as physical fitness, activity and functional capacity, will be investigated in children with asthma.

Conditions

Asthma in Children

Keywords

Asthma Childhood; Respiratory Muscle; Physical Activity; Fitness

Outcome Measures

Primary Outcomes (2)

• Dynamic Respiratory Muscle Strength and Endurance

  POWERbreathe K-Series, K5, intelligent digital breathing trainers, The first 2 breaths should be taken as quickly and deeply as possible. During these breaths, the maximum respiratory capacity is measured. The index of the power indicator ranges from 10 to 240 cm H2O. Higher values are better. For hygiene reasons, the test is done with a disposable mouthpiece.

  Day 1

• Pulmonary Function Test

  It is evaluated with the Pulmonary Function Test. After a deep, full inspiration, a forced expiratory maneuver is performed. Used with disposable antiviral filter. The patient's height and body weight are measured and recorded with age. It is done 3 times, there should be no more than 10% difference between the values. The highest value is accepted.

  Day 1

Secondary Outcomes (7)

• 6 Minutes Walking Test

  Day 1

• Physical Activity Questionnaire

  Day 1

• FITNESSGRAM (a) Sit and lie down test with back support:

  Day 1

• FITNESSGRAM (b) Trunk Extension-extension test:

  Day 1

• FITNESSGRAM (c) Trunk Flexion flexion test:

  Day 1

Study Arms (2)

Asthmatic Child

Children with asthma between 6-11 years old

Healthy Controls Group

Healthy children between 6-11 years old

Eligibility Criteria

• Age: 6 Years - 11 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

asthmatic child and healthly peers

You may qualify if:

• Hacettepe University Faculty of Medicine, Department of Pediatrics, Allergy and Asthma Unit patients referred for Cardiopulmonary Rehabilitation,
• Those who have been diagnosed with asthma,
• Clinically stable and not in active asthma attack,
• Between the ages of 6-11,
• Giving consent on a voluntary basis,
• cooperative,

You may not qualify if:

• Those whose clinical status is not stable and who are in active asthma attack,
• Having serious diseases such as cancers, heart failure and acute respiratory infections,
• Having chronic lung disease other than asthma,
• Severe neuromuscular and musculoskeletal problems,
• Uncooperative to do the tests,
• For safety reasons, patients admitted or hospitalized in the last 3 months due to an asthma attack will not be included in the study.
• Not having any chronic disease for healthy individuals,
• be between the ages of 6-11,
• Volunteering to participate in the study,
• Not having speech and hearing problems,
• Being cooperative,
• Not having a mental, neurological, orthopedic, cardiovascular or pulmonary problem that would prevent physical activity,
• The presence of a medical indication that requires complete restriction of physical activity,
• Having symptoms of any chronic or acute illness involving the lungs
• Existence of cooperation and communication problems

Sponsors & Collaborators

• Bartın Unıversity: lead
• Hacettepe University: collaborator

Study Sites (1)

Ebru Çalik Kütükcü

Ankara, Altındağ, 06100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• Ebru Calik Kutukcu, PhD

  Hacettepe University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: August 9, 2023
• First Posted: September 26, 2023
• Study Start: March 13, 2023
• Primary Completion: December 13, 2023
• Study Completion: March 10, 2024
• Last Updated: August 9, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)