Bizarreness and Anomalous Self Experiences in Schizophrenia

NCT05966610 | Unknown

• 2 other identifiers: RC31/22/05172023-A00049-36
• Study Type: observational
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia. However, determining factors of this phenomena, whether cognitive or subjective, remains poorly studied. Furthermore, Self-Disorders are alterations of the first-person experience regarded as specific of the disease. The investigators plan to study in an exploratory way the phenomenological and subjective links between Praecox Feeling and Self Disorders determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.

Conditions

Schizophrenia

Keywords

Praecox Feeling; Self-Disorders; Subjectivity; Cognition

Outcome Measures

Primary Outcomes (1)

• Correlation between Praecox Feeling and Self Disorders

  Comparison between Examination of Anomalous Subjective Experience (EASE) total score evaluated at third visit and mean of Praecox Feeling intensity measured by a visual analog scale (VAS) evaluated at each visit. Examination of Anomalous Subjective Experience is a 5-item interview asked by the investigator. Visual Analog Scale (VAS) is a scale that evaluates the level of strangeness felt during the patient/investigator encounter. It goes from 0 (no strangeness feeling) to 100 (maximal strangeness feeling).

  2 months

Secondary Outcomes (3)

• Correlation between Praecox Feeling and symptomatic dimensions

  2 months

• Correlation between Praecox Feeling intensity and Self Disorders intensity

  2 months

• Correlation between the patient's judgment and the quality of the meeting

  2 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Stabilised patients with schizophrenia

You may qualify if:

• People with a diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria.
• Psychiatric medical situation judged clinically stable : no change of main antipsychotic in treatment in last 15 days.
• People who has given his non-opposition
• Patients affiliated to a social security system

You may not qualify if:

• Previous meeting of the participant with one of the investigators involved in the clinical assessment and scoring of the study scales.
• Person with a moderate to severe intellectual disability (clinical criteria).
• Person with a neurological pathology with cognitive impact
• Patients with legal protection

Sponsors & Collaborators

• University Hospital, Toulouse: lead

Study Sites (1)

CHU Toulouse

Toulouse, France

RECRUITING

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Officials

• Tudi GOZE, MD

  University Hospital, Toulouse

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Tudi GOZE, MD

CONTACT

5 61 77 23 60; goze.t@chu-toulouse.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 30, 2023
• First Posted: July 28, 2023
• Study Start: July 12, 2023
• Primary Completion: July 1, 2024
• Study Completion: September 1, 2024
• Last Updated: July 28, 2023

Record last verified: 2023-07

Locations

FR (1)