Study of Intra- and Interpersonal Multimodal Synchronizations in a Social Interaction in Individuals with a Diagnosis of Schizophrenia.
ENHANCER1
Study of Multimodal Intra- and Interpersonal Synchronizations in Social Interaction in Individuals with a Diagnosis of Schizophrenia.
1 other identifier
interventional
120
1 country
1
Brief Summary
The aim of this study is to precisely identify deficits in intra- and interpersonal multimodal synchronizations during social interaction in individuals with schizophrenia (ISZ). During a social interaction, individuals use both visual and auditory channels to construct their discourse. The auditory channel encompasses the semantics and prosody of the speech, while the visual channel describes the entirety of non-verbal gestures (e.g., facial expressions, body movements). Prosody and non-verbal gestures are essential elements for the speaker. By accompanying speech, they contribute to the planning and conceptualization of the utterance and enhance its communicative power. For the listener, prosody and non-verbal gestures are also used to provide sensory feedback to the speaker. Several studies have shown the existence of intrapersonal and interpersonal synchronizations of prosody and non-verbal gestures during interaction. These synchronizations are associated with numerous social benefits (e.g., increased mutual appreciation and quality of interaction). However, certain mental disorders, such as schizophrenia, exhibit deficits in non-verbal behaviors that can impair these synchronizations and the associated social benefits. We hypothetized that interaction with individuals with a daignosis of schizophrenia will be associated with deficits in intra and interpersonal synchronization.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable schizophrenia
Started Nov 2024
Shorter than P25 for not_applicable schizophrenia
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 26, 2024
CompletedFirst Posted
Study publicly available on registry
July 3, 2024
CompletedStudy Start
First participant enrolled
November 8, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 8, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
November 8, 2025
CompletedDecember 9, 2024
December 1, 2024
1 year
June 26, 2024
December 4, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
interpersonal synchronization
synchronization between body movements of two interacting partners
4x6 minutes
intrapersonal synchronization
synchronization between voice and body movements of one individual
4x6 minutes
Secondary Outcomes (2)
correlation between primary outcomes and individuals with schizophrenia medications
4x6 minutes
correlation between synchronization and willingness to continue the interaction
4x6 minutes
Study Arms (2)
dyad schizophrenia and interacting partner
EXPERIMENTALsocial interaction between an individual with a diagnosis of schizophrenia and his interacting partner
dyad healthy subject and interacting partner
EXPERIMENTALsocial interaction between a healthy subject and his interacting partner
Interventions
Participants are required to speak to one another. Participants are given various topics of conversation.
Eligibility Criteria
You may qualify if:
- diagnosis of schizophrenia according to the DSM-V
- being able to read, speak and understand french
- giving eclaired consent
You may not qualify if:
- history of head trauma
- history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke)
- substance use
- pregnant women
- Healthy controls :
- being able to read, speak and understand french
- giving eclaired consent
- diagnosis of psychosis
- history of head trauma
- history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke)
- substance use
- pregnant women
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University Hospital, Montpellierlead
- Euromov Digital Health in Motioncollaborator
Study Sites (1)
Montpellier University Hospital
Montpellier, 34000, France
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 26, 2024
First Posted
July 3, 2024
Study Start
November 8, 2024
Primary Completion
November 8, 2025
Study Completion
November 8, 2025
Last Updated
December 9, 2024
Record last verified: 2024-12
Data Sharing
- IPD Sharing
- Will not share