A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
ROCKET-ASCEND
A Phase 3, Multicenter, Double-blind Maintenance Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASCEND)
2 other identifiers
interventional
2,621
39 countries
537
Brief Summary
The primary objective of this study is to describe the long-term safety and tolerability of rocatinlimab in participants with moderate-to-severe AD.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started May 2023
Typical duration for phase_3
537 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 22, 2023
CompletedFirst Posted
Study publicly available on registry
May 31, 2023
CompletedStudy Start
First participant enrolled
May 31, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 22, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 22, 2026
May 4, 2026
April 1, 2026
3.1 years
May 22, 2023
April 28, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number of Participants With Treatment-emergent Adverse Events
Up to 116 weeks
Secondary Outcomes (6)
Maintaining Validated Investigator's Global Assessment for Atopic Dermatitis (vIGA-AD™) 0/1 Response at Week 32 Among Participants Achieving vIGA-AD™ 0/1 Response at Day 1
Week 32
Maintaining a Revised IGA (rIGA™) 0/1 Response at Week 32 Among Participants Achieving rIGA™ 0/1 Response at Day 1
Week 32
Maintaining Eczema Area and Severity Index (EASI) 75 Response at Week 32 Among Participants Achieving EASI 75 Response at Day 1
Week 32
Maintaining EASI 90 Response at Week 32 Among Participants Achieving EASI 90 Response at Day 1
Week 32
Maintaining vIGA-AD™ 0/1 Response and EASI 75 Response at Week 32 Among Participants Achieving vIGA-AD™ 0/1 Response and EASI 75 Response at Day 1
Week 32
- +1 more secondary outcomes
Study Arms (7)
ARM A: Dose 1 to Dose 1
EXPERIMENTALParticipants from parent Rocatinlimab studies ROCKET-Ignite, ROCKET-Horizon, ROCKET-SHUTTLE, or ROCKET-ASTRO who received Dose 1 will be randomized or assigned to receive Dose 1 Every 4 Weeks (Q4W) or Every 8 Weeks (Q8W). Participants from parent Rocatinlimab study ROCKET-VOYAGER who received Dose 1 will be assigned to receive Dose 1 Q4W.
ARM B: Dose 2 to Dose 2
EXPERIMENTALParticipants from parent Rocatinlimab studies ROCKET-Ignite, ROCKET-SHUTTLE, or ROCKET-ASTRO who received Dose 2 will be randomized or assigned to receive Dose 2 Q4W or Q8W.
ARM C: Dose 1 or Dose 2 to Placebo
PLACEBO COMPARATORParticipants from parent Rocatinlimab studies ROCKET-Ignite or ROCKET-Horizon who received Dose 1 will be randomized to receive placebo Q4W. Participants from parent Rocatinlimab study ROCKET-Ignite who received Dose 2 will be randomized to receive placebo Q4W.
ARM D: Placebo to Placebo
PLACEBO COMPARATORParticipants from parent Rocatinlimab studies ROCKET- Ignite, ROCKET-Horizon, ROCKET-SHUTTLE, ROCKET-ASTRO, or ROCKET-VOYAGER who received placebo will be randomized or assigned to receive placebo Q4W.
ARM E: Dose 1, Dose 2, Placebo, or Open-label (OL) to OL Dose 1
EXPERIMENTALParticipants from parent Rocatinlimab studies ROCKET- Ignite, ROCKET-Horizon, ROCKET- SHUTTLE, ROCKET-ASTRO, or ROCKET-VOYAGER who received Dose 1, Dose 2, or placebo will be assigned to receive OL Rocatinlimab Dose 1 Q4W. Participants who received OL in parent Rocatinlimab study ROCKET- ASTRO will continue to receive OL Rocatinlimab Dose 1 Q4W. All participants from parent Rocatinlimab study ROCKET-Orbit will continue to receive OL Rocatinlimab Dose 1 Q4W.
ARM F Group
NO INTERVENTIONParticipants in Arm E (OL Rocatinlimab Dose 1 Q4W) who meet defined criteria will have Rocatinlimab withdrawn, but will continue all subsequent study visits.
ARM G Group
EXPERIMENTALParticipants from Arm F who meet defined criteria will resume OL Rocatinlimab Dose 1 Q4W.
Interventions
Subcutaneous (SC) injection
Eligibility Criteria
You may qualify if:
- Completion of an end of treatment duration visit (Week 24 or Week 52 visit for adult or adolescent studies, respectively) in a rocatinlimab parent study (ROCKET-IGNITE, ROCKET-HORIZON, ROCKET-SHUTTLE, ROCKET-ASTRO, ROCKET-ORBIT, OR ROCKET-VOYAGER) within the past 28 days.
- Participants from the parent study ROCKET-ORBIT must achieve an improvement in EASI score at week 52 of at least 60% compared to parent study baseline (EASI 60).
You may not qualify if:
- Permanent investigational product discontinuation due to safety-related reasons, protocol-defined stopping rules or conditions/reasons unrelated to efficacy during the rocatinlimab parent study (ROCKET-IGNITE, ROCKET-HORIZON, ROCKET-SHUTTLE, ROCKET-ASTRO, ROCKET-ORBIT, OR ROCKET-VOYAGER), or at the time of Screening or Day 1.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Amgenlead
Study Sites (547)
Cahaba Dermatology and Skin Health Center
Birmingham, Alabama, 35244, United States
Medical Dermatology Specialists
Phoenix, Arizona, 85006, United States
Alliance Dermatology and Mohs Center
Phoenix, Arizona, 85032, United States
Affiliated Dermatology
Scottsdale, Arizona, 85255, United States
Scottsdale Clinical Trials
Scottsdale, Arizona, 85260, United States
Dermatology Trial Associates
Bryant, Arkansas, 72022, United States
Burke Pharmaceutical Research
Hot Springs, Arkansas, 71913, United States
Arkansas Research Trials, LLC
North Little Rock, Arkansas, 72117, United States
Kern Research Inc
Bakersfield, California, 93301, United States
Hope Clinical Research LLC
Canoga Park, California, 91303, United States
West Coast Research LLC
Dublin, California, 94568, United States
California Dermatology and Clinical Research Institute
Encinitas, California, 92024, United States
First OC Dermatology
Fountain Valley, California, 92708, United States
Antelope Valley Clinical Trials
Lancaster, California, 93534, United States
Chemidox Clinical Trials Incorporated
Lancaster, California, 93534, United States
Long Beach Research Institute
Long Beach, California, 90805, United States
University of California Los Angeles
Los Angeles, California, 90024, United States
Dermatology Research Associates
Los Angeles, California, 90045, United States
Wallace Medical Group Inc
Los Angeles, California, 90056, United States
Northridge Clinical Trials
Northridge, California, 91325, United States
University of California Irvine
Orange, California, 92868, United States
Havana Research Institute Inc
Pasadena, California, 91105, United States
Integrative Skin Science and Research
Sacramento, California, 95815, United States
University of California at Davis Medical Center
Sacramento, California, 95816, United States
Kaiser Permanente South Sacramento Medical Center
Sacramento, California, 95823, United States
Alliance Clinical Research
San Diego, California, 92120, United States
Kaiser Permanente Medical Center - Oakland
San Francisco, California, 94118, United States
Kaiser Permanente Medical Center - San Francisco
San Francisco, California, 94118, United States
Wolverine Clinical Trials
Santa Ana, California, 92706, United States
Clinical Science Institute
Santa Monica, California, 90404, United States
IMMUNOe Research Centers
Centennial, Colorado, 80112, United States
Skin Care Research Incorporated
Boca Raton, Florida, 33486, United States
Renaissance Research and Medical Group
Cape Coral, Florida, 33991, United States
Driven Research LLC
Coral Gables, Florida, 33134, United States
Corazon United States of America, LLC doing business as Life Clinical Trials
Coral Springs, Florida, 33071, United States
D and H Doral Research Centers
Doral, Florida, 33122, United States
Saint Jude Clinical Research
Doral, Florida, 33172, United States
Direct Helpers Research Center
Hialeah, Florida, 33012, United States
Global Research Solutions
Homestead, Florida, 33030, United States
Nexus Clinical Research
Homestead, Florida, 33033, United States
Glick Skin Institute
Margate, Florida, 33063, United States
ara Professionals Limited Liability Corporation
Miami, Florida, 33155, United States
Gold Coast Health Research Center
Miami, Florida, 33155, United States
Miami Clinical Research
Miami, Florida, 33155, United States
Healthy Life Research
Miami, Florida, 33175, United States
Anchor Medical Research
Miami, Florida, 33176, United States
Meridian International Research
Miami Gardens, Florida, 33014, United States
Savin Medical Group LLC
Miami Lakes, Florida, 33014, United States
Clinical Associates of Orlando Limited Liability Company
Orlando, Florida, 32819, United States
Innovation Medical Research Center Inc
Palmetto Bay, Florida, 33157, United States
University of South Florida
Tampa, Florida, 33612, United States
Olympian Clinical Research - Tampa
Tampa, Florida, 33615, United States
Atlanta Dermatology, Vein and Research Center, PC
Alpharetta, Georgia, 30022, United States
First Georgia Physicians Group
Fayetteville, Georgia, 30214, United States
Advanced Medical Research PC
Sandy Springs, Georgia, 30328, United States
Treasure Valley Medical Research
Boise, Idaho, 83706, United States
DeNova Research
Chicago, Illinois, 60602, United States
Sneeze, Wheeze, and Itch Associates, LLC
Normal, Illinois, 61761, United States
Endeavor Health Clinical Trials Center
Skokie, Illinois, 60077, United States
Dundee Dermatology
West Dundee, Illinois, 60118, United States
DS Research
Clarksville, Indiana, 47129, United States
Dawes Fretzin Clinical Research Group, LLC
Indianapolis, Indiana, 46250, United States
Southern Indiana Clinical Trials
New Albany, Indiana, 47150, United States
The Indiana Clinical Trials Center PC
Plainfield, Indiana, 46168, United States
Options Research Group LLC
West Lafayette, Indiana, 47906, United States
Dermatology and Skin Cancer Center Leawood
Leawood, Kansas, 66211, United States
DS Research
Louisville, Kentucky, 40241, United States
Kentucky Advanced Medical Research LLC
Murray, Kentucky, 42071, United States
Foxhall Research Center
Chevy Chase, Maryland, 20815, United States
Institute for Asthma and Allergy
Chevy Chase, Maryland, 20815, United States
Continental Clinical Solutions, LLC
Towson, Maryland, 21204, United States
MetroBoston Clinical Partners
Brighton, Massachusetts, 02135, United States
University of Michigan
Ann Arbor, Michigan, 48109, United States
Henry Ford Medical Center - New Center One
Detroit, Michigan, 48202, United States
Onyx Clinical Research
Flint, Michigan, 48532, United States
Revival Research Institute LLC
Troy, Michigan, 48084, United States
Somerset Skin Centre
Troy, Michigan, 48084, United States
Dermatology and Skin Cancer Center of Lees Summit
Lee's Summit, Missouri, 64064, United States
Saint Louis University
St Louis, Missouri, 63110, United States
Somnos Clinical Research
Lincoln, Nebraska, 68505, United States
Jubilee Clinical Research Inc
Las Vegas, Nevada, 89106, United States
Excel Clinical Research
Las Vegas, Nevada, 89109, United States
Las Vegas Clinical Trials
North Las Vegas, Nevada, 89030, United States
Skin Cancer and Dermatology Institute
Reno, Nevada, 89509, United States
Albuquerque Clinical Trials Incorporated
Albuquerque, New Mexico, 87102, United States
Forest Hills Dermatology Group
Kew Gardens, New York, 11415, United States
Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
Sadick Research Group
New York, New York, 10075, United States
OptiSkin Medical
New York, New York, 10128, United States
Chear Center LLC
The Bronx, New York, 10455, United States
DJL Clinical Research PLLC
Charlotte, North Carolina, 28211, United States
Wilmington Dermatology Center
Wilmington, North Carolina, 28405, United States
Accellacare of Wilmington
Wilmington, North Carolina, 28411, United States
The Skin Surgery Center for Clinical Research
Winston-Salem, North Carolina, 27103, United States
Bexley Dermatology Research
Bexley, Ohio, 43209, United States
Bernstein Clinical Research Center LLC
Cincinnati, Ohio, 45236, United States
The Ohio State University
Gahanna, Ohio, 43230, United States
Apex Clinical Research Center LLC
Mayfield Heights, Ohio, 44124, United States
Dermatologist of Central States Clinical Research - Springfield
Springfield, Ohio, 45505, United States
Unity Clinical Research
Oklahoma City, Oklahoma, 73118, United States
Dermatology Research Center of Oklahoma, PLLC
Tulsa, Oklahoma, 74132, United States
Essential Medical Research LLC
Tulsa, Oklahoma, 74145, United States
Velocity Clinical Research Medford
Medford, Oregon, 97504, United States
Oregon Medical Research Center
Portland, Oregon, 97201, United States
Oregon Dermatology and Research Center
Portland, Oregon, 97210, United States
Best Skin Research
Camp Hill, Pennsylvania, 17011, United States
Paddington Testing Company Inc
Philadelphia, Pennsylvania, 19103, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Health Concepts
Rapid City, South Dakota, 57702, United States
Cumberland Skin Center
Hermitage, Tennessee, 37076, United States
US Dermatology Partners Jollyville
Austin, Texas, 78759, United States
Bellaire Dermatology Associates
Bellaire, Texas, 77401, United States
US Dermatology Partners Cedar Park
Cedar Park, Texas, 78613, United States
Driscoll Childrens Hospital
Corpus Christi, Texas, 78411, United States
Alina Clinical Trials, LLC
Dallas, Texas, 75225, United States
Dermatology Treatment and Research Center PA
Dallas, Texas, 75230, United States
Zenos Clinical Research
Dallas, Texas, 75230, United States
Texas Dermatology Research Center
Dallas, Texas, 75246, United States
Newco 3A Research LLC
El Paso, Texas, 79925, United States
Center For Clinical Studies PLLC
Houston, Texas, 77004, United States
University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
Sante Clinical Research
Kerrville, Texas, 78028, United States
Long and Harris Dermatology
Lubbock, Texas, 79424, United States
Sms Clinical Research Limited Liability Company
Mesquite, Texas, 75149, United States
Stride Clinical Research LLC
Missouri City, Texas, 77459, United States
Texas Dermatology and Laser Specialists
San Antonio, Texas, 78218, United States
Dermatology Clinical Research Center of San Antonio
San Antonio, Texas, 78229, United States
Stryde Research Epiphany Dermatology
Southlake, Texas, 76092, United States
The Woodlands Dermatology Associates
The Woodlands, Texas, 77380, United States
Tanner Clinic
Murray, Utah, 84107, United States
University of Utah MidValley Dermatology
Murray, Utah, 84107, United States
Education and Research Foundation Inc
Forest, Virginia, 24551, United States
Virginia Dermatology and Skin Cancer Center
Norfolk, Virginia, 23502, United States
Eastern Virginia Medical School
Norfolk, Virginia, 23507, United States
MultiCare Institute for Research and Innovation
Spokane, Washington, 99202, United States
Conexa Investigacion Clinica SA
CABA, Buenos Aires, C1012AAY, Argentina
Cinme - Centro de Investigaciones Metabolicas
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1056ABI, Argentina
Fundacion Respirar
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1426ABP, Argentina
Hospital Universitario Austral
Derqui, Pilar, Buenos Aires, B1629ODT, Argentina
Framingham Centro Medico
La Plata, Buenos Aires, B1902COS, Argentina
Buenos Aires Skin SA
Buenos Aires, Distrito Federal, 1054, Argentina
Fundacion Cidea
Buenos Aires, Distrito Federal, 1121, Argentina
Care- Centro de Alergia y Enfermedades Respiratorias
Buenos Aires, Distrito Federal, 1414, Argentina
Instituto de Neumonologia y Dermatologia
Buenos Aires, Distrito Federal, 1425, Argentina
Psoriahue Medicina Interdisciplinaria SRL
Buenos Aires, Distrito Federal, 1425, Argentina
InAER - Investigaciones en Alergia y Enfermedades Respiratorias
CABA, Distrito Federal, 1425, Argentina
Centro de Investigaciones Clinicas Instituto Especialidades De La Salud De Rosario
Rosario, Santa Fe Province, 2000, Argentina
Fundacion Estudios Clinicos
Rosario, Santa Fe Province, 2000, Argentina
Instituto de Diagnostico abc
Rosario, Santa Fe Province, 2000, Argentina
Premier Specialists
Kogarah, New South Wales, 2217, Australia
St George Dermatology and Skin Cancer Centre
Kogarah, New South Wales, 2217, Australia
Liverpool Hospital
Liverpool, New South Wales, 2170, Australia
Royal North Shore Hospital
St Leonards, New South Wales, 2065, Australia
The Skin Centre
Benowa, Queensland, 4217, Australia
Princess Alexandra Hospital
South Brisbane, Queensland, 4101, Australia
Veracity Clinical Research
Woolloongabba, Queensland, 4102, Australia
Box Hill Hospital
Box Hill, Victoria, 3128, Australia
Emeritus Research Camberwell
Camberwell, Victoria, 3124, Australia
Skin Health Institute
Carlton, Victoria, 3053, Australia
Monash Childrens Hospital
Clayton, Victoria, 3168, Australia
The Alfred Hospital
Melbourne, Victoria, 3004, Australia
Institute for Skin Health and Immunity
Mitcham, Victoria, 3132, Australia
The Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
Medizinische Universitaet Graz
Graz, 8036, Austria
Landeskrankenhaus Salzburg
Salzburg, 5020, Austria
Universite Catholique de Louvain Cliniques Universitaires Saint Luc
Brussels, 1200, Belgium
Grand Hopital de Charleroi - Site des Viviers
Charleroi, 6060, Belgium
Universitair Ziekenhuis Gent
Ghent, 9000, Belgium
Clinique Andre Renard
Herstal, 4040, Belgium
Dermatologie Handelskaai
Kortrijk, 8500, Belgium
Centre Hospitalier Universitaire de Liege - Sart Tilman
Liège, 4000, Belgium
Dermatologie Maldegem
Maldegem, 9990, Belgium
Centro do Diagnostico e Pesquisa da Osteoporose do Espirito Santo
Vitória, Espírito Santo, 29055-450, Brazil
Clinica Instituto Bahiano de Imunoterapia - Medicina, Reumatologia e Dermatologia ltda
Salvador, Estado de Bahia, 41820-020, Brazil
Centro de Pesquisa Clínica da Universidade de Belo Horizonte - Unibh
Belo Horizonte, Minas Gerais, 30575-180, Brazil
Ceti Centro Est Terap Inovadoras
Curitiba, Paraná, 80030-110, Brazil
Universidade Federal do Parana
Curitiba, Paraná, 80060-240, Brazil
Irmandade da Santa Casa de Misericordia de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Hospital de Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hospital Ernesto Dornelles
Porto Alegre, Rio Grande do Sul, 90160-093, Brazil
Alergoalfa Nucleo Diagnostico Tratamento e Pesquisa Clinica em Alergia
Barueri, São Paulo, 06454-010, Brazil
Cecip Centro Est Clin Int Paulista
Jaú, São Paulo, 17201-130, Brazil
Fundacao Abc - Centro Univ Fmabc
Santo André, São Paulo, 09060-870, Brazil
Cemec Centro Multidisciplinar Estudos Clinicos
São Bernardo do Campo, São Paulo, 09715-090, Brazil
Hospital de Base de Sao Jose do Rio Preto
São José do Rio Preto, São Paulo, 15090-000, Brazil
Ispem - Instituto Sao Jose dos Campos em Pesquisas Medicas
São José dos Campos, São Paulo, 12243-280, Brazil
Instituto Pesquisa e Ensino em Saúde Infantil
São Paulo, São Paulo, 01228-200, Brazil
Sociedade Beneficente de Senhoras Hospital Sirio Libanes
São Paulo, São Paulo, 01308-050, Brazil
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, São Paulo, 05403-002, Brazil
Consultoria Medica e Pesquisa Clinica Cmpc
Sorocaba, São Paulo, 18040-425, Brazil
IBPClin Instituto Brasil de Pesquisa Clinica
Rio de Janeiro, 20241-180, Brazil
Medical Center Asklepii OOD
Dupnitsa, 2600, Bulgaria
Medical Center Medconsult Pleven OOD
Pleven, 5800, Bulgaria
Medical Center Excelsior OOD
Sofia, 1407, Bulgaria
Diagnostic-Consultative Center Alexandrovska EOOD
Sofia, 1431, Bulgaria
Diagnostic-Consultative Center - Fokus-5 - Medical Institution for Outpatient Care OOD
Sofia, 1463, Bulgaria
Dermatology Research Institute Incorporated
Calgary, Alberta, T2J 7E1, Canada
Beacon Dermatology
Calgary, Alberta, T3E 0B2, Canada
Rejuvenation Dermatology Laser Calgary North
Calgary, Alberta, T3K 6B8, Canada
Laser Rejuvenation Clinics Edmonton D T Incorporated
Edmonton, Alberta, T5J 3S9, Canada
Stratica Dermatology
Edmonton, Alberta, T5K 1X3, Canada
Alberta Derma Surgery Centre
Edmonton, Alberta, T6G 1C3, Canada
Vida Clinical Research
Edmonton, Alberta, T6H 4J8, Canada
Skin Physicians Dermatology
Edmonton, Alberta, T6W 4V4, Canada
Interior Dermatology Centre
Kelowna, British Columbia, V1W 4V5, Canada
Doctor Chih-Ho Hong Medical Incorporated
Surrey, British Columbia, V3R 6A7, Canada
Enverus Medical Research
Surrey, British Columbia, V3V 0C6, Canada
Winnipeg Clinic Dermatology Research
Winnipeg, Manitoba, R3C 0N2, Canada
Wiseman Dermatology Research Incorporated
Winnipeg, Manitoba, R3M 3Z4, Canada
Karma Clinical Trials
St. John's, Newfoundland and Labrador, A1A 4Y3, Canada
CCA Medical Research Corp
Ajax, Ontario, L1S 7K8, Canada
SimcoDerm Medical and Surgical Dermatology Centre
Barrie, Ontario, L4M 7G1, Canada
Halton Pediatric Allergy
Burlington, Ontario, L7L 6W6, Canada
SKiN Health
Coburg, Ontario, K9A 0Z4, Canada
Kingsway Clinical Research
Etobicoke, Ontario, M8X 1Y9, Canada
Guelph Dermatology Research
Guelph, Ontario, N1L 0B7, Canada
LEADER Research
Hamilton, Ontario, L8L 3C3, Canada
Triple A Lab
Hamilton, Ontario, L8S 1G5, Canada
Centricity Research London Victoria
London, Ontario, N6A 2C2, Canada
Lynderm Research Inc
Markham, Ontario, L3P 1X3, Canada
DermEdge Research Incorporated
Mississauga, Ontario, L4Y 4C5, Canada
Ryan Clinical Research Incorporated
Newmarket, Ontario, L3Y 5G8, Canada
Allergy Research Canada Incorporated
Niagara Falls, Ontario, L2H 1H5, Canada
North Bay Dermatology Centre
North Bay, Ontario, P1B 3Z7, Canada
Canadian Dermatology Centre
North York, Ontario, M3B 0A7, Canada
The Centre for Clinical Trials Inc
Oakville, Ontario, L6J 7W5, Canada
JRB Research Incorporated
Ottawa, Ontario, K1K 4L2, Canada
Dermatology Ottawa Research Centre
Ottawa, Ontario, K2C 3N2, Canada
SKiN Centre for Dermatology
Peterborough, Ontario, K9J 5K2, Canada
The Centre for Dermatology
Richmond Hill, Ontario, L4B 1A5, Canada
York Dermatology Clinic and Research Centre
Richmond Hill, Ontario, L4B 1L1, Canada
Oak Ridges Aesthetics Centre
Richmond Hill, Ontario, L4E 4L6, Canada
North York Research Incorporated
Toronto, Ontario, M2N 3A6, Canada
Toronto Research Centre Inc
Toronto, Ontario, M3H 5Y8, Canada
FACET Dermatology
Toronto, Ontario, M4E 1R7, Canada
Research Toronto
Toronto, Ontario, M4W 2N4, Canada
Evidence Based Medical Educator Inc
Toronto, Ontario, M5G 1E2, Canada
Alliance Clinical Trials
Waterloo, Ontario, N2J 1C4, Canada
XLR8 Medical Research, Incorporated
Windsor, Ontario, N8T 1E6, Canada
Clinique de Dermatologie Rosemont
Montreal, Quebec, H1Y 3L1, Canada
Innovaderm Research Inc
Montreal, Quebec, H2X 2V1, Canada
Recherche Clinique Sigma Incorporated
Québec, Quebec, G1G 3Y8, Canada
Centre de Recherche Dermatologique du Quebec Metropolitain
Québec, Quebec, G1V 4X7, Canada
Clinique Medicale Saint Louis
Québec, Quebec, G1W 4R4, Canada
Skinsense Medical Research
Saskatoon, Saskatchewan, S7K 2C1, Canada
Saskatoon Dermatology Centre
Saskatoon, Saskatchewan, S7T 0G3, Canada
Hospital Base San Jose de Osorno
Osorno, 5311523, Chile
Centro Medico Skinmed Spa
Santiago, 7580206, Chile
Clinica Dermacross SA
Santiago, 7640881, Chile
Fundacion Innovacion Cardiovascular Clinica Ensenada
Santiago, 8380465, Chile
Centro Internacional de Estudios Clinicos
Santiago, Chile
Peking University Peoples Hospital
Beijing, Beijing Municipality, 100044, China
Beijing Childrens Hospital, Capital Medical University
Beijing, Beijing Municipality, 100045, China
Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, 100050, China
Peking University Third Hospital
Beijing, Beijing Municipality, 100191, China
Childrens Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 400014, China
The First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, 350005, China
The First Affiliated Hospital Sun-Yat Sen University
Guangzhou, Guangdong, 510080, China
Dermatology Hospital of Southern Medical University
Guangzhou, Guangdong, 510091, China
Sun Yat-sen Memorial Hospital Sun Yat-sen University
Guangzhou, Guangdong, 510120, China
The Fist Affiliated Hospital of Shantou University Medical College
Shantou, Guangdong, 515041, China
Shenzhen Childrens Hospital
Shenzhen, Guangdong, 518038, China
The First Hospital Of Hebei Medical University
Shijiazhuang, Hebei, 050000, China
Nanyang First Peoples Hospital
Nanyang, Henan, 473002, China
Sanmenxia Central Hospital
Sanmenxia, Henan, 472099, China
The Central Hospital of Wuhan
Wuhan, Hubei, 430014, China
Union Hospital Tongji Medical College Huazhong University of Science and Technology
Wuhan, Hubei, 430022, China
Hunan Childrens Hospital
Changsha, Hunan, 410007, China
The Second Xiangya Hospital of Central South University
Changsha, Hunan, 410011, China
Wuxi Second Peoples Hospital
Wuxi, Jiangsu, 214001, China
Wuxi Peoples Hospital
Wuxi, Jiangsu, 241023, China
Dermatology Hospital of Jiangxi Province
Nanchang, Jiangxi, 330000, China
The First Bethune Hospital of Jilin University
Changchun, Jilin, 130021, China
The First Hospital of China Medical University
Shenyang, Liaoning, 110001, China
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, 750004, China
Shanghai Skin Disease Hospital
Shanghai, Shanghai Municipality, 200443, China
Chengdu Second Peoples Hospital
Chengdu, Sichuan, 610021, China
Suining Central Hospital
Suining, Sichuan, 629099, China
Kunming Childrens Hospital
Kunming, Yunnan, 650103, China
Zhejiang Provincial Peoples Hospital
Hangzhou, Zhejiang, 310014, China
Affiliated Hangzhou First Peoples Hospital School of Medicine Westlake University
Hangzhou, Zhejiang, 310020, China
Ningbo NO 2 Hospital
Ningbo, Zhejiang, 315010, China
The First Affiliation Hospital Of Ningbo University
Ningbo, Zhejiang, 315010, China
Taizhou Central Hospital
Taizhou, Zhejiang, 318000, China
Special Hospital for Medical Rehabilitation Naftalan
Ivanić-Grad, 10310, Croatia
Children s Hospital Zagreb
Zagreb, 10000, Croatia
University Hospital Centre Zagreb
Zagreb, 10000, Croatia
Kozni ambulance Kutna Hora sro
Kutná Hora, 284 01, Czechia
Dermamedica, sro
Náchod, 547 01, Czechia
Nemocnice Novy Jicin as
Nový Jičín, 741 01, Czechia
CCR Ostrava sro
Ostrava, 702 00, Czechia
Pratia Pardubice as
Pardubice, 530 02, Czechia
Fakultni nemocnice Plzen
Pilsen, 305 99, Czechia
Clintrial sro
Prague, 100 00, Czechia
Dermamedest sro
Prague, 120 00, Czechia
Pratia Prague sro
Prague, 130 00, Czechia
Kozni ambulance Fialova sro
Prague, 160 00, Czechia
Fakultni nemocnice Bulovka
Prague, 180 81, Czechia
Praglandia sro
Praha 5 - Smichov, 150 00, Czechia
Dermatologicka ambulance MUDr Petr Trestik
Svitavy, 568 02, Czechia
Krajska zdravotni as - Masarykova nemocnice Usti nad Labem oz
Ústí nad Labem, 401 13, Czechia
Gentofte Hospital
Hellerup, 2900, Denmark
North Estonia Medical Centre
Tallinn, 13419, Estonia
Clinical Research Centre
Tartu, 50106, Estonia
Clinical Research Services Helsinki
Helsinki, 00180, Finland
Oulun Yliopistollinen sairaala
Oulu, 90029, Finland
Terveystalo Tampere
Tampere, 33100, Finland
Hopital Prive d Antony
Antony, 92160, France
Polyclinique de Courlancy
Bezannes, 51430, France
Centre Hospitalier Regional Universitaire de Brest - Hopital Morvan
Brest, 29200, France
Centre Hospitalier Regional Universitaire de Lille - Hopital Claude Huriez
Lille, 59037, France
Centre Hospitalier de Bretagne Sud - Hopital du Scorff
Lorient, 56322, France
Cabinet du Docteur Ruer-Mulard Mireille
Martigues, 13500, France
Centre Hospitalier Universitaire Archet 2
Nice, 06202, France
Hopital Saint Louis
Paris, 75475, France
Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou
Rennes, 35033, France
Centre Hospitalier Universitaire de Rouen - Hopital Charles Nicolle
Rouen, 76000, France
Fachklinik Bad Bentheim
Bad Bentheim, 48455, Germany
Charite - Universitaetsmedizin Berlin, Campus Mitte
Berlin, 10117, Germany
Clinical Research Services Berlin GmbH
Berlin, 13672, Germany
Hautarztpraxis Dr Niesmann und Dr Othlinghaus
Bochum, 44793, Germany
Rosenpark Research GmbH
Darmstadt, 64283, Germany
Universitaetsklinikum Dresden
Dresden, 01307, Germany
Universitaetsklinikum Frankfurt
Frankfurt am Main, 60590, Germany
Universitaetsmedizin Goettingen - Georg-August-Universitaet
Göttingen, 37075, Germany
Institute for Health Services Research in Dermatology and Nursing
Hamburg, 20246, Germany
Hautaerzte Zentrum Hannover
Hanover, 30159, Germany
Universitaetsklinikum Heidelberg
Heidelberg, 69120, Germany
Universitaetsklinikum Schleswig-Holstein - Kiel
Kiel, 24105, Germany
Velocity Clinical Research
Leipzig, 04177, Germany
Dermatologische Gemeinschaftspraxis-Mahlow
Mahlow, 15831, Germany
Universitaetsmedizin Mainz
Mainz, 55101, Germany
Beldio Research GmbH
Memmingen, 87700, Germany
Hautmedizin Saar
Merzing, 66663, Germany
Klinikum rechts der Isar der TUM
München, 80802, Germany
Universitaetsklinikum Muenster
Münster, 48149, Germany
KliFOs Klinische Forschung Osnabrueck
Osnabrück, 49074, Germany
Hautarztpraxis Mortazawi
Remscheid, 42897, Germany
Hautarztpraxis Dres Leitz und Kollegen
Stuttgart, 70178, Germany
Universitaetsklinikum Tuebingen
Tübingen, 72076, Germany
Helios Klinikum Wuppertal
Wuppertal, 42283, Germany
CentroDerm GmbH
Wuppertal, 42287, Germany
University General Hospital Attikon
Athens, 12462, Greece
Andreas Syngros Hospital Of Venereal And Dermatological Diseases
Athens, 16121, Greece
University General Hospital of Ioannina
Ioannina, 45500, Greece
General University Hospital of Larissa
Larissa, 41110, Greece
General Hospital Of Nea Ionia Konstantopouleio Patision
Nea Ionia, 14233, Greece
Geniko Nosokomeio Peiraia Tzaneio
Piraeus, 18536, Greece
Papageorgiou General Hospital
Thessaloniki, 56429, Greece
Queen Mary Hospital, The University of Hong Kong
Hong Kong, Hong Kong
Trial Pharma Kft
Békéscsaba, 5600, Hungary
Csalogany Orvosi Kozpont
Budapest, 1027, Hungary
Clinexpert Kft
Budapest, 1033, Hungary
Obudai Egeszsegugyi Centrum Kft
Budapest, 1036, Hungary
Debreceni Egyetem Klinikai Kozpont
Debrecen, 4032, Hungary
Gyongyosi Bugat Pal Korhaz
Gyöngyös, 3200, Hungary
Somogy Varmegyei Kaposi Mor Oktato Korhaz
Kaposvár, 7400, Hungary
DermaMed Research Kft
Orosháza, 5900, Hungary
Allergo-Derm Bakos Kft
Szolnok, 5000, Hungary
Medmare Bt
Veszprém, 8200, Hungary
Obudai Egeszsegugyi Centrum Kft
Zalaegerszeg, 8900, Hungary
Sheba Medical Center
Ramat Gan, 5262000, Israel
Universita degli Studi Gabriele D Annunzio di Chieti e Pescara
Chieti, 66100, Italy
Ospedale San Salvatore
LAquila, 67100, Italy
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
Milan, 20122, Italy
Azienda Ospedaliera Universitaria Luigi Vanvitelli
Naples, 80131, Italy
Azienda Ospedaliera di Perugia Ospedale Santa Maria della Misericordia
Perugia, 06156, Italy
Azienda Ospedaliera Policlinico Umberto I
Roma, 00161, Italy
IRCCS Istituto Clinico Humanitas
Rozzano MI, 20089, Italy
Azienda Ospedaliera Citta della Salute e della Scienza di Torino
Torino, 10126, Italy
Aichi Medical University Hospital
Nagakute-shi, Aichi-ken, 480-1195, Japan
Fukui Dermatology Clinic
Nagoya, Aichi-ken, 454-0803, Japan
Japan Community Healthcare Organization Chukyo Hospital
Nagoya, Aichi-ken, 457-8510, Japan
Central Clinic
Nagoya, Aichi-ken, 464-0821, Japan
Nagoya City University Hospital
Nagoya, Aichi-ken, 467-8602, Japan
Miyata Dermatology Clinic
Matsudo-shi, Chiba, 271-0092, Japan
International University of Health and Welfare Narita Hospital
Narita-shi, Chiba, 286-8520, Japan
Ekihigashi Dermatology Allergy Clinic
Fukuoka, Fukuoka, 812-0013, Japan
Fukuoka University Hospital
Fukuoka, Fukuoka, 814-0180, Japan
Matsuo Clinic
Fukuoka, Fukuoka, 819-0373, Japan
Fukushima Medical University Hospital
Fukushima, Fukushima, 960-1295, Japan
Asahikawa City Hospital
Asahikawa-shi, Hokkaido, 070-8610, Japan
Takagi Dermatological Clinic
Obihiro-shi, Hokkaido, 080-0013, Japan
Medical Corporation Kojinkai Sapporo Skin Clinic
Sapporo, Hokkaido, 060-0063, Japan
Yoshimura Child Clinic
Akashi-shi, Hyōgo, 674-0068, Japan
Kobe University Hospital
Kobe, Hyōgo, 650-0017, Japan
Tokyo Medical University Ibaraki Medical Center
Inashiki-gun, Ibaraki, 300-0395, Japan
Kaji Dermatology Clinic
Nonoichi-shi, Ishikawa-ken, 921-8801, Japan
Iwate Medical University Uchimaru Medical Center
Morioka, Iwate, 020-8505, Japan
Takeoka Dermatology Clinic
Marugame-shi, Kagawa-ken, 763-0074, Japan
Katahira Dermatology Urology Clinic
Kagoshima, Kagoshima-ken, 890-0063, Japan
Kosugi Dermatology Clinic
Kawasaki-shi, Kanagawa, 211-0063, Japan
Nippon Medical School Musashikosugi Hospital
Kawasaki-shi, Kanagawa, 211-8533, Japan
St Marianna University Hospital
Kawasaki-shi, Kanagawa, 216-8511, Japan
National Hospital Organization Sagamihara National Hospital
Sagamihara-shi, Kanagawa, 252-0392, Japan
Nomura Dermatology Clinic
Yokohama, Kanagawa, 221-0825, Japan
Showa Medical University Northern Yokohama Hospital
Yokohama, Kanagawa, 224-8503, Japan
Yokohama City Minato Red Cross Hospital
Yokohama, Kanagawa, 231-8682, Japan
Jouzan Hihuka Hinyoukika Clinic
Kumamoto, Kumamoto, 860-0066, Japan
Suizenji Dermatology Clinic
Kumamoto, Kumamoto, 862-0950, Japan
University Hospital Kyoto Prefectural University of Medicine
Kyoto, Kyoto, 602-8566, Japan
Rakuwakai Otowa Hospital
Kyoto, Kyoto, 607-8062, Japan
Nagasaki University Hospital
Nagasaki, Nagasaki, 852-8501, Japan
Osaka Habikino Medical Center
Habikino-shi, Osaka, 583-8588, Japan
Mochida Dermatology Clinic
Izumiotsu-shi, Osaka, 595-0025, Japan
Yoshioka Dermatology Clinic
Neyagawa, Osaka, 572-0838, Japan
Dermatology and Ophthalmology Kume Clinic
Sakai-shi, Osaka, 593-8324, Japan
JA Shizuoka Kohseiren Enshu Hospital
Hamamatsu, Shizuoka, 430-0929, Japan
Hamamatsu University Hospital
Hamamatsu, Shizuoka, 431-3192, Japan
Dokkyo Medical University Hospital
Shimotsuga-gun, Tochigi, 321-0293, Japan
Mildix Skin Clinic
Adachi-ku, Tokyo, 120-0034, Japan
Teikyo University Hospital
Itabashi-ku, Tokyo, 173-8606, Japan
Nihon University Itabashi Hospital
Itabashi-ku, Tokyo, 173-8610, Japan
Mita Dermatology Clinic
Minato-ku, Tokyo, 108-0014, Japan
Naoko Dermatology Clinic
Setagaya-ku, Tokyo, 158-0097, Japan
NTT Medical Center Tokyo
Shinagawa-ku, Tokyo, 141-8625, Japan
Showa Medical University Hospital
Shinagawa-ku, Tokyo, 142-8666, Japan
Seibo International Catholic Hospital
Shinjuku-ku, Tokyo, 161-8521, Japan
Yamate Dermatology Clinic
Shinjuku-ku, Tokyo, 169-0075, Japan
Sugamo Kobayashi Derma Clinic
Toshima-ku, Tokyo, 170-0002, Japan
Shirasaki Dermatology Clinic
Takaoka-shi, Toyama, 933-0871, Japan
Outpatient clinic Veselibas Centrs 4
Riga, 1003, Latvia
Outpatient clinic Veselibascentrs 4
Riga, LV-1013, Latvia
Smite Aija practice in dermatology and venerology
Talsi, 3201, Latvia
Hospital Sultan Ismail
Johor Bahru, Johor, 81100, Malaysia
University Malaya Medical Centre
Kuala Lumpur, Kuala Lumpur, 59100, Malaysia
Hospital Raja Permaisuri Bainun
Ipoh, Perak, 30450, Malaysia
Hospital Pulau Pinang
George Town, Pulau Pinang, 10990, Malaysia
Clínica de Enfermedades Crónicas y de Procedimientos Especiales
Morelia, Michoacán, 58249, Mexico
Phylasis Clinical Research
Cuautitlán Izcalli, 54750, Mexico
Bravis Ziekenhuis
Bergen op Zoom, 4624 VT, Netherlands
Universitair Medisch Centrum Groningen
Groningen, 9700 RB, Netherlands
Universitair Medisch Centrum Utrecht
Utrecht, 3584 CX, Netherlands
ClinicMed Daniluk Nowak Spolka komandytowa
Bialystok, 15-879, Poland
Dermapolis Medical Dermatology Center dr n med Edyta Gebska
Chorzów, 41-500, Poland
Uniwersyteckie Centrum Kliniczne
Gdansk, 80-214, Poland
AKK Medical Spolka z ograniczona odpowiedzialnoscia Centrum Medyczne Tu sie leczy
Gdansk, 80-280, Poland
GynCentrum Spzoo NZOZ Holsamed - Oddzial Libero
Katowice, 40-600, Poland
Centrum Medyczne Angelius Provita
Katowice, 40-611, Poland
Specjalistyczny Gabinet Dermatologiczny Aplikacyjno-Badawczy Marek Brzewski Pawel Brzewski SpCywilna
Krakow, 30-002, Poland
Diamond Clinic Spolka z Ograniczona Odpowiedzialnoscia Diamond Medical Center
Krakow, 31-559, Poland
Centrum Terapii Wspolczesnej J M Jasnorzewska Spolka Komandytowo Akcyjna
Lodz, 90-338, Poland
AppleTreeClinics Network Spzoo
Lodz, 90-349, Poland
Ip Clinic Sp zoo
Lodz, 90-752, Poland
Amicare Spolka z ograniczona odpowiedzialnoscia Spolka Komandytowa Amicare Centrum Medyczne
Lodz, 91-495, Poland
Clinical Best Solutions Sp zoo Spolka Komandytowa
Lublin, 20-011, Poland
Centrum Zdrowia i Urody Maxxmed
Lublin, 20-080, Poland
Centrum Badawcze Panaceum Agnieszka Brzezicka Magdalena Lenkiewicz Spzoo
Malbork, 82-200, Poland
Twoja przychodnia Ncm
Nowa Sól, 67-100, Poland
Twoja przychodnia Pcm
Poznan, 60-324, Poland
Centrum Zdrowia Dziecka i Rodziny Im Jana Pawla II w Sosnowcu Osrodek Badan Klinicznych
Sosnowiec, 41-200, Poland
Twoja Przychodnia Scm
Szczecin, 71-500, Poland
Alergo-Med Osrodek Badan Klinicznych sp zoo
Tarnów, 33-100, Poland
Klinika Osipowicz and Turkowski Sp zoo
Warsaw, 00-716, Poland
High Med Przychodnia Specjalistyczna
Warsaw, 01-817, Poland
Evimed sp zoo centrum medyczne evimed
Warsaw, 02-625, Poland
Klinika Ambroziak Dermatologia
Warsaw, 02-953, Poland
Royalderm Agnieszka Nawrocka
Warsaw, 02-962, Poland
DermMedica Spzoo Centrum Columbus
Wroclaw, 51-503, Poland
Dermaceum Spolka z Ograniczona Odpowiedzialnoscia Dermaceum Centrum Medyczne
Wroclaw, 53-613, Poland
Unidade de Saude Local de Almada-Seixal, EPE - Hospital Garcia de Orta
Almada, 2801-951, Portugal
Unidade Local de Saude de Coimbra, EPE
Coimbra, 3000-075, Portugal
Hospital Cuf Descobertas
Lisbon, 1998-018, Portugal
Unidade Local de Saude de Santo Antonio, EPE - Hospital de Santo Antonio
Porto, 4099-001, Portugal
Unidade Local de Saude de Sao Joao, EPE - Hospital de Sao Joao
Porto, 4200-319, Portugal
Gcm Medical Group, Psc
San Juan, 00917, Puerto Rico
Derma Cluj
Cluj-Napoca, 400105, Romania
National University Hospital
Singapore, 119074, Singapore
Singapore General Hospital
Singapore, 168753, Singapore
National Skin Centre
Singapore, 308205, Singapore
Fakultna Nemocnica s poliklinikou F D Roosevelta Banska Bystrica
Banská Bystrica, 975 17, Slovakia
Maxderm, sro
Bardejov, 085 01, Slovakia
Univerzitna nemocnica Bratislava - Nemocnica Stare Mesto
Bratislava, 813 69, Slovakia
Derma therapy, spol s ro
Bratislava, 851 01, Slovakia
Sanare spol sro
Svidník, 089 01, Slovakia
Kaderma Majtan, sro
Topoľčany, 955 01, Slovakia
Univerzitetni klinicni center Ljubljana
Ljubljana, 1000, Slovenia
Univerzitetni Klinicni Center Maribor
Maribor, 2000, Slovenia
Hiway Medical Centre
Westville, Durban, KwaZulu-Natal, 3630, South Africa
Korea University Ansan Hospital
Ansansi, Gyeonggido, 15355, South Korea
SoonChunHyang University Hospital Bucheon
Bucheon-si, Gyeonggi-do, 14584, South Korea
Chosun University Hospital
Gwangju, 61453, South Korea
The Catholic University of Korea Incheon St Marys Hospital
Incheon, 21431, South Korea
Inha University Hospital
Incheon, 22332, South Korea
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
Korea University Anam Hospital
Seoul, 02841, South Korea
Seoul National University Hospital
Seoul, 03080, South Korea
Severance Hospital Yonsei University Health System
Seoul, 03722, South Korea
National Medical Center
Seoul, 04564, South Korea
Konkuk University Medical Center
Seoul, 05030, South Korea
Kyung Hee University Hospital at Gangdong
Seoul, 05278, South Korea
Asan Medical Center
Seoul, 05505, South Korea
The Catholic University of Korea Seoul St Marys Hospital
Seoul, 06591, South Korea
Chung-Ang University Hospital
Seoul, 06973, South Korea
Hallym University Kangnam Sacred Heart Hospital
Seoul, 07441, South Korea
Ewha Womans University Seoul Hospital
Seoul, 07804, South Korea
Korea University Guro Hospital
Seoul, 08308, South Korea
Ajou University Hospital
Suwon-si, Gyeonggi-do, 16499, South Korea
Hospital Universitario Reina Sofia
Córdoba, Andalusia, 14004, Spain
Hospital Universitario Virgen Macarena
Seville, Andalusia, 41009, Spain
Hospital Universitario Basurto
Bilbao, Basque Country, 48013, Spain
Hospital Universitario de Gran Canaria Doctor Negrin
Las Palmas de Gran Canaria, Canary Islands, 35010, Spain
Hospital Universitari Germans Trias i Pujol
Badalona, Catalonia, 08916, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, Catalonia, 08025, Spain
Hospital Universitari de Bellvitge
L'Hospitalet de Llobregat, Catalonia, 08907, Spain
Hospital Clinico Universitario de Santiago
Santiago de Compostela, Galicia, 15706, Spain
Hospital Universitario Quironsalud Madrid
Pozuelo de Alarcón, Madrid, 28223, Spain
Clinica Universidad de Navarra
Pamplona, Navarre, 31008, Spain
Hospital General Universitario de Alicante
Alicante, Valencia, 03010, Spain
Hospital de Manises
Manises, Valencia, 46940, Spain
Hospital Arnau de Vilanova de Valencia
Valencia, Valencia, 46015, Spain
Hospital Universitario de La Princesa
Madrid, 28006, Spain
Hospital General Universitario Gregorio Maranon
Madrid, 28007, Spain
Hospital Universitario Infanta Leonor
Madrid, 28031, Spain
Hospital Universitario Ramon y Cajal
Madrid, 28034, Spain
Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
Hospital Universitario La Paz
Madrid, 28046, Spain
Hospital Universitario Miguel Servet
Zaragoza, 50009, Spain
Inselspital Bern
Bern, 3010, Switzerland
Centre Hospitalier Universitaire Vaudois
Lausanne, 1011, Switzerland
Universitaetsspital Zuerich
Zurich, 8091, Switzerland
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, 83301, Taiwan
National Cheng Kung University Hospital
Tainan, 70403, Taiwan
National Taiwan University Hospital
Taipei, 10002, Taiwan
Mackay Memorial Hospital Taipei Branch
Taipei, 10449, Taiwan
Taipei Veterans General Hospital
Taipei, 11217, Taiwan
Linkou Chang Gung Memorial Hospital
Taoyuan, 33305, Taiwan
King Chulalongkorn Memorial Hospital
Bangkok, 10330, Thailand
Siriraj Hospital
Bangkok, 10700, Thailand
Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, 50200, Thailand
Thammasat University Hospital
Pathum Thani, 12120, Thailand
Ankara Bilkent Sehir Hastanesi
Ankara, 06800, Turkey (Türkiye)
Gaziantep Universitesi Tip Fakultesi Hastanesi
Gaziantep, 27310, Turkey (Türkiye)
Istanbul Universitesi Istanbul Tip Fakultesi Hastanesi
Istanbul, 34390, Turkey (Türkiye)
Acibadem Altunizade Hastanesi
Istanbul, 34662, Turkey (Türkiye)
Marmara Universitesi Tip Fakultesi Hastanesi
Istanbul, 34899, Turkey (Türkiye)
Bakircay Universitesi Cigli Egitim ve Arastirma Hastanesi
Izmir, 35620, Turkey (Türkiye)
Erciyes Universitesi Tip Fakultesi Hastanesi
Kayseri, 38030, Turkey (Türkiye)
Kocaeli Universitesi Tip Fakultesi Hastanesi
Kocaeli, 41380, Turkey (Türkiye)
Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi
Samsun, 55200, Turkey (Türkiye)
Alder Hey Childrens Hospital
Liverpool, L12 2AP, United Kingdom
Whipps Cross University Hospital
London, E11 1NR, United Kingdom
The Royal Free Hospital
London, NW3 2PF, United Kingdom
Guys Hospital
London, SE1 9RT, United Kingdom
Salford Care Organisation
Salford, M6 8HD, United Kingdom
Accellacare Yorkshire
Shipley, BD18 3SA, United Kingdom
Related Publications (1)
Guttman-Yassky E, Simpson E, Bissonnette R, Eichenfield LF, Kabashima K, Luna PC, Hercogova JT, Spelman L, Worm M, Esfandiari E, Arai T, Mano H, Charuworn P, Wang A, Kricorian G. ROCKET: a phase 3 program evaluating the efficacy and safety of rocatinlimab in moderate-to-severe atopic dermatitis. Immunotherapy. 2025 Feb;17(2):83-94. doi: 10.1080/1750743X.2025.2464528. Epub 2025 Feb 26.
PMID: 40012373BACKGROUND
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
MD
Amgen
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 22, 2023
First Posted
May 31, 2023
Study Start
May 31, 2023
Primary Completion (Estimated)
June 22, 2026
Study Completion (Estimated)
June 22, 2026
Last Updated
May 4, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF, CSR
- Time Frame
- Data sharing requests relating to this study will be considered beginning 18 months after the study has ended and either 1) the product and indication have been granted marketing authorization in both the US and Europe or 2) clinical development for the product and/or indication discontinues and the data will not be submitted to regulatory authorities. There is no end date for eligibility to submit a data sharing request for this study.
- Access Criteria
- Qualified researchers may submit a request containing the research objectives, the Amgen product(s) and Amgen study/studies in scope, endpoints/outcomes of interest, statistical analysis plan, data requirements, publication plan, and qualifications of the researcher(s). In general, Amgen does not grant external requests for individual patient data for the purpose of re-evaluating safety and efficacy issues already addressed in the product labelling. Requests are reviewed by a committee of internal advisors. If not approved, a Data Sharing Independent Review Panel will arbitrate and make the final decision. Upon approval, information necessary to address the research question will be provided under the terms of a data sharing agreement. This may include anonymized individual patient data and/or available supporting documents, containing fragments of analysis code where provided in analysis specifications. Further details are available at the URL below.
De-identified individual patient data for variables necessary to address the specific research question in an approved data sharing request.