Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 30/100

Failure Rate

14.3%

223 terminated/withdrawn out of 1564 trials

Success Rate

82.8%

-3.7% vs industry average

Late-Stage Pipeline

30%

472 trials in Phase 3/4

Results Transparency

63%

675 of 1074 completed trials have results

Key Signals

94 recruiting675 with results180 terminated43 withdrawn

Enrollment Performance

Analytics

Phase 2
479(34.2%)
Phase 1
392(28.0%)
Phase 3
351(25.1%)
Phase 4
121(8.6%)
N/A
45(3.2%)
Early Phase 1
12(0.9%)
1400Total
Phase 2(479)
Phase 1(392)
Phase 3(351)
Phase 4(121)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (1564)

Showing 20 of 1564 trials
NCT07293260Phase 3Recruiting

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

Role: lead

NCT07136012Phase 3Recruiting

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

Role: lead

NCT07213674Phase 3Recruiting

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Role: lead

NCT07037459Phase 3Recruiting

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Role: lead

NCT04608474Phase 4Completed

Lipid Management in Renal Transplant Recipients Using Evolocumab.

Role: collaborator

NCT07226765Phase 3Recruiting

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

Role: lead

NCT04822337Phase 1Active Not Recruiting

Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple Myeloma

Role: collaborator

NCT07005128Phase 3Recruiting

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Role: lead

NCT07225686Phase 3Recruiting

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

Role: lead

NCT07297979Phase 1Recruiting

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

Role: lead

NCT07441252Phase 2Recruiting

A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

Role: lead

NCT07422285Phase 1Recruiting

Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcutaneous Dose

Role: lead

NCT04521231Phase 1Recruiting

A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL

Role: lead

NCT04994717Phase 3Recruiting

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

Role: lead

NCT07531095Phase 1Not Yet Recruiting

Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)

Role: lead

NCT02876107Phase 2Active Not Recruiting

Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Breast Cancer

Role: collaborator

NCT06117774Phase 3Recruiting

Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)

Role: lead

NCT07192237Phase 2Not Yet Recruiting

Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Patients With Measurable Residual Disease Positive B-cell Acute Lymphoblastic Leukemia

Role: collaborator

NCT07111507Phase 2Recruiting

A Study of Tarlatamab for People With Prostate Cancer

Role: collaborator

NCT06502977Phase 2Active Not Recruiting

Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment

Role: lead