NCT05845788

Brief Summary

The investigators aimed to compare the effects of ultrasound guided erector spina plan block and posterior quadratus lumborum block on intraoperative and postoperative opioid consumption in patients who will undergo short segment lumbar stabilization surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 9, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

April 15, 2023

Completed
21 days until next milestone

First Posted

Study publicly available on registry

May 6, 2023

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 2, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 2, 2023

Completed
Last Updated

November 2, 2023

Status Verified

October 1, 2023

Enrollment Period

4 months

First QC Date

March 9, 2023

Last Update Submit

October 31, 2023

Conditions

Postprocedural AnalgesiaOpioid ConsumptionErector Spina Plan BlockQuadratus Lumborum Block

Outcome Measures

Primary Outcomes (7)

  • İntraoperative remifentanil consumption

    The investigators aimed to compare intraoperative remifentanil consumption of two groups

    At the end of the intraoperative period

  • Postoperative tramadol consumption

    The investigators aimed to compare postoperative tramadol consumption of two groups

    The investigators will record at postoperative 0. hour

  • Postoperative tramadol consumption

    The investigators aimed to compare postoperative tramadol consumption of two groups

    The investigators will record at postoperative 1. hour

  • Postoperative tramadol consumption

    The investigators aimed to compare postoperative tramadol consumption of two groups

    The investigators will record at postoperative 2. hour

  • Postoperative tramadol consumption

    The investigators aimed to compare postoperative tramadol consumption of two groups

    The investigators will record at postoperative 6. hour

  • Postoperative tramadol consumption

    The investigators aimed to compare postoperative tramadol consumption of two groups

    The investigators will record at postoperative 12. hour

  • Postoperative tramadol consumption

    The investigators aimed to compare postoperative tramadol consumption of two groups

    The investigators will record at postoperative 24. hour

Secondary Outcomes (8)

  • Postoperative nausea and vomiting

    The investigators will record within 24 hours postoperatively.

  • Postoperative pruritus

    The investigators will record within 24 hours postoperatively.

  • Postoperative visual analog scale

    The investigators will record at postoperative 0. hour

  • Postoperative visual analog scale

    We will record at postoperative 1. hour

  • Postoperative visual analog scale

    The investigators will record at postoperative 2. hour

  • +3 more secondary outcomes

Other Outcomes (21)

  • Postoperative pulse rate

    The investigators will record at postoperative 0. hour

  • Postoperative pulse rate

    The investigators will record at postoperative 1. hour

  • Postoperative pulse rate

    The investigators will record at postoperative 2. hour

  • +18 more other outcomes

Study Arms (2)

Erector Spina Plan Block Group (Group E)

Patients who underwent erector spina plane block before initiation of surgery after induction of anesthesia

Procedure: Peripheral nerve block

Posterior Quadratus Lumborum Block Group ( Group Q)

Patients who underwent posterior quadratus lumborum block block before initiation of surgery after induction of anesthesia

Procedure: Peripheral nerve block

Interventions

Peripheral nerve blockPROCEDURE

Ultrasound guided peripheral nerve block

Erector Spina Plan Block Group (Group E)Posterior Quadratus Lumborum Block Group ( Group Q)

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients who will undergo lumbar stabilization operation under general anesthesia in Ankara Bilkent City Hospital Operating Room, between the ages of 18-65, both genders, and in the ASA I-III risk group will be included in the study.

You may qualify if:

  • Patients who will undergo lumbar stabilization operation
  • Between the ages of 18-65
  • Both genders
  • ASA I-III risk group

You may not qualify if:

  • Patients who did not accept the study
  • Patients younger than 18 years old
  • Patients older than 65 years
  • Patients with an ASA score greater than III
  • Patients with an active infection in the area to be blocked
  • Patients with a long bleeding time
  • Those who are pregnant
  • Patients with kidney failure
  • Patients with liver failure
  • Patients with BMI\<18 and BMI\>30
  • Those who are allergic to local anesthetics
  • Patients who have had previous lumbar surgery
  • Uncooperative or mentally retarded patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ankara City Hospital, Bilkent

Ankara, Cankaya, Turkey (Türkiye)

Location

Related Publications (4)

  • Qiu Y, Zhang TJ, Hua Z. Erector Spinae Plane Block for Lumbar Spinal Surgery: A Systematic Review. J Pain Res. 2020 Jul 1;13:1611-1619. doi: 10.2147/JPR.S256205. eCollection 2020.

    PMID: 32669870BACKGROUND

  • Dhanjal ST, Tonder S. Quadratus Lumborum Block. 2023 Aug 14. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK537212/

    PMID: 30725897BACKGROUND

  • Elsharkawy H, El-Boghdadly K, Barrington M. Quadratus Lumborum Block: Anatomical Concepts, Mechanisms, and Techniques. Anesthesiology. 2019 Feb;130(2):322-335. doi: 10.1097/ALN.0000000000002524. No abstract available.

    PMID: 30688787BACKGROUND

  • Kang R, Lee S, Kim GS, Jeong JS, Gwak MS, Kim JM, Choi GS, Cho YJ, Ko JS. Comparison of Analgesic Efficacy of Erector Spinae Plane Block and Posterior Quadratus Lumborum Block in Laparoscopic Liver Resection: A Randomized Controlled Trial. J Pain Res. 2021 Dec 11;14:3791-3800. doi: 10.2147/JPR.S343366. eCollection 2021.

    PMID: 34924770BACKGROUND

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 9, 2023

First Posted

May 6, 2023

Study Start

April 15, 2023

Primary Completion

August 2, 2023

Study Completion

August 2, 2023

Last Updated

November 2, 2023

Record last verified: 2023-10

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)