Develop a Novel Occupational Training Program for Schizophrenia Patients Based on Virtual Reality Techniques
1 other identifier
interventional
40
1 country
1
Brief Summary
Establish a novel vocational training program and test its validity in a pilot study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable schizophrenia
Started Jan 2020
Longer than P75 for not_applicable schizophrenia
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 4, 2019
CompletedStudy Start
First participant enrolled
January 1, 2020
CompletedFirst Posted
Study publicly available on registry
April 26, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2026
February 27, 2026
February 1, 2026
7 years
July 4, 2019
February 24, 2026
Conditions
Outcome Measures
Primary Outcomes (3)
clinical ratings of schizophrenia symptoms
The Positive and Negative Syndrome Scale (PANSS) is a 30-item rating scale completed by trained research staff. Scores for positive, negative, cognitive disorganization, emotional discomfort, and hostility/excitement symptoms were derived from factor-derived scoring published. \* There are 30 different symptoms rated from 1 to 7 (total score of 210). Higher the score, worse the symptoms
8 weeks
vocational skills
Job interview role-play performance will be scored across nine domains: conveying oneself as a hard worker, sounding easy to work with, conveying that one behaves professionally, negotiation skills (requesting one day off), sharing things in a positive way, sounding honest, sounding interested in the position, comfort level, and establishing rapport
8 weeks
global improvement
Clinical Global Impression Improvement scale (CGI-I) rating scales are commonly used measures of symptom severity, treatment response and the efficacy in treatment studies of patients with mental disorders. It is a 7-point scale that require clinician to assess how much the patient's illness has improved or worsened relative to baseline. "1" meaning very much improved, "7" meaning very much worsen.
8 weeks
Study Arms (4)
Mild ED/NS
EXPERIMENTAL10 patients with mild or none executive function impairment and mild or none negative symptoms.
Mild ED/Severe NS
EXPERIMENTAL10 patients with mild or none executive function impairment and severe or moderate negative symptoms.
Severe ED/Mild NS
EXPERIMENTAL10 patients with severe or moderate executive function impairment and mild or none negative symptoms.
Severe ED/NS
EXPERIMENTAL10 patients with severe or moderate executive function impairment and severe or moderate negative symptoms.
Interventions
VR-assisted occupational training
Eligibility Criteria
You may qualify if:
- Having a diagnosis of schizophrenia based on the Diagnostic and Statistical Manual of Mental Disorders -5th version
- Aged between 20 and 55 years.
- Motivated to have a job.
- Having a full-scale IQ \> 70 on the Wechsler Adult Intelligence Scale-version IV.
- Having a PANSS positive scale \< 70, indicating a stable condition during the illness course.
You may not qualify if:
- Comorbid with other major psychiatric disorders (i.e., bipolar disorders) or neurological diseases.
- Substance abuse within one year.
- Visual impairment and/or hearing impairment that would preclude participation in the VR-based training program.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University Hospital
Taipei, Taiwan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Yi Ling Chien
National Taiwan University Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SEQUENTIAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 4, 2019
First Posted
April 26, 2023
Study Start
January 1, 2020
Primary Completion (Estimated)
December 31, 2026
Study Completion (Estimated)
December 31, 2026
Last Updated
February 27, 2026
Record last verified: 2026-02